Background
Methods
Statistical analysis
Results
Comorbidity
Fracture group n = 50 | Control group n = 150 | p- values | |
---|---|---|---|
Mean age, years (95% CI) | 64.5 (63.5-65.6) | 65.1 (64.4-65.7) | 0.677 a |
Gender, w/m (%) | 38 (76%) / 12 (24%) | 116 (77.3%) / 34 (22.7%) | 0.846 b |
Mean BMI (kg/m2) (95% CI) | 24.2 (23.1-25.4) | 26.7 (26.0-27.4) | 0.001c |
Diabetes mellitus, n (%) | 5 (10%) | 5 (3.33%) | 0.061b |
Smoking, n (%) | 24 (48%) | 15 (10%) | < 0.001b |
Mean Charlson Comorbidity Index Score total (95% CI) n (%) | 2.64 (2.39-2.89) | 2.14 (2.04-2.24) | 0.001b |
1 | 3 (6%) | 19 (12.7%) | |
2 | 20 (40%) | 94 (62.7%) | |
3 | 21 (42%) | 34 (22.7%) | |
4 | 4 (8%) | 3 (2%) | |
5 | 2 (4%) | 0 | |
ASA score, n (%)d | < 0.001b | ||
1 | 6 (12%) | 73 (48.7%) | |
2 | 31 (62%) | 74 (49.3%) | |
3 | 13 (26%) | 3 (2%) | |
4 | 0 | 0 |
Hip function
Fracture group n = 50 | Control group n = 150 | p-values | |
---|---|---|---|
Mean Harris Hip Score (95% CI) | 93.6 (91.0-96.3) | 97.1 (95.8-98.4) | < 0.001a |
Mean Oxford Hip Score (95% CI) | 46.2 (44.8-47.2) | 46.0 (45.4-47.0) | 0.173 a |
Mean HOOS (95%CI) Pain | 92.9 (89.1-96.7) | 95.3 (93.5-97.1) | 0.226 a |
Symptoms | 94.3 (90.6-97.7) | 95.2 (93.4-97.0) | 0.226 a |
ADL | 92.4 (87.3-97.5) | 95.7 (93.9-97.5) | 0.244 a |
Sport | 89.9 (83.6-96.2) | 92.1 (89.3-94.8) | 0.739 a |
QoL | 94.0 (89.7-98.4) | 93.6 (90.9-96.4) | 0.792 a |
Bone mineral density
Dual-energy X-ray absorptiometry | Fracture group n = 50/45 hips n (%) | Control group n = 150 n (%) | p-values |
---|---|---|---|
Lumbar spine T-score | 0.003 a | ||
T-score >-1 | 19 (38%) | 83 (55%) | |
T-score - 1- -2.5 | 17 (34%) | 53 (35%) | |
T-score ≤ -2.5 | 14 (28%) | 14 (9%) | |
Hip total T-score b | < 0.001 a | ||
T-score >-1 | 8 (18%) | 79 (53%) | |
T-score - 1 - -2.5 | 22 (49%) | 63 (42%) | |
T-score ≤ -2.5 | 15 (33%) | 8 (5%) | |
Hip femoral neck T-score b | < 0.001 a | ||
T-score >-1 | 4 (9%) | 47 (31%) | |
T-score- 1 - -2.5 | 21 (47%) | 85 (57%) | |
T-score ≤ -2.5 | 20 (44%) | 18 (12%) |
Risk analysis
Unadjusted | Adjusted a | |||||
---|---|---|---|---|---|---|
OR | 95%CI | p-values | OR | 95%CI | p-values | |
Smoking | 8.3 | 3.8-17.9 | < 0.001 | 6.8 | 2.8-16.1 | < 0.001 |
Charlson Comorbidity Index Score | 2.6 | 1.6-4.1 | < 0.001 | 2.0 | 1.2-3.6 | 0.011 |
DXA femoral neck T-score > -1 normal bone | 1 | < 0.001 | 1 | < 0.001 | ||
DXA femoral neck T-score- 1 - -2.5 osteopenia | 3.1 | 1.0-9.6 | 0.049 | 2.1 | 0.6-6.9 | 0.236 |
DXA femoral neck T-score ≤ -2.5 osteoporosis | 13.6 | 4.1-45.3 | < 0.001 | 7.6 | 2.1-27.9 | < 0.001 |