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Osteoporosis International

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01.11.2011 | Case Report

Low bone turnover and increase of bone mineral density in a premenopausal woman with postoperative hypoparathyroidism and thyroxine suppressive therapy

verfasst von: K. Amrein, H. P. Dimai, H. Dobnig, A. Fahrleitner-Pammer

Erschienen in: Osteoporosis International | Ausgabe 11/2011

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Abstract

We report the case of a 36-year-old woman who developed permanent hypoparathyroidism after thyroidectomy for differentiated thyroid carcinoma. A 6-year follow-up showed an increase of 11% in absolute bone mineral density at the spine and 6% at the hip accompanied by low bone turnover despite thyroid-stimulating hormone suppressive thyroxine therapy.

Asari R, Passler C, Kaczirek K, Scheuba C, Niederle B (2008) Hypoparathyroidism after total thyroidectomy: a prospective study. Arch Surg 143:132–137, discussion 138PubMedCrossRef

Thomusch O, Machens A, Sekulla C, Ukkat J, Brauckhoff M, Dralle H (2003) The impact of surgical technique on postoperative hypoparathyroidism in bilateral thyroid surgery: a multivariate analysis of 5846 consecutive patients. Surgery 133:180–185PubMedCrossRef

Roher HD, Goretzki PE, Hellmann P, Witte J (1999) Complications in thyroid surgery. incidence and therapy. Chirurg 70:999–1010PubMedCrossRef

Dralle H (2009) Identification of the recurrent laryngeal nerve and parathyroids in thyroid surgery. Chirurg 80:352–363PubMedCrossRef

Testini M, Gurrado A, Lissidini G, Nacchiero M (2007) Hypoparathyroidism after total thyroidectomy. Minerva Chir 62:409–415PubMed

Thomusch O, Machens A, Sekulla C, Ukkat J, Lippert H, Gastinger I, Dralle H (2000) Multivariate analysis of risk factors for postoperative complications in benign goiter surgery: prospective multicenter study in Germany. World J Surg 24:1335–1341PubMedCrossRef

Chen Q, Kaji H, Iu MF, Nomura R, Sowa H, Yamauchi M, Tsukamoto T, Sugimoto T, Chihara K (2003) Effects of an excess and a deficiency of endogenous parathyroid hormone on volumetric bone mineral density and bone geometry determined by peripheral quantitative computed tomography in female subjects. J Clin Endocrinol Metab 88:4655–4658PubMedCrossRef

Abugassa S, Nordenstrom J, Eriksson S, Sjoden G (1993) Bone mineral density in patients with chronic hypoparathyroidism. J Clin Endocrinol Metab 76:1617–1621PubMedCrossRef

Chan FK, Tiu SC, Choi KL, Choi CH, Kong AP, Shek CC (2003) Increased bone mineral density in patients with chronic hypoparathyroidism. J Clin Endocrinol Metab 88:3155–3159PubMedCrossRef

10.

Duan Y, De Luca V, Seeman E (1999) Parathyroid hormone deficiency and excess: similar effects on trabecular bone but differing effects on cortical bone. J Clin Endocrinol Metab 84:718–722PubMedCrossRef

11.

Hawkins F, Escobar-Jimenez F, Jodar E, Campos MM, Lopez Alvarez MB, Martinez Diaz-Guerra G (2003) Bone mineral density in hypoparathyroid women on LT4 suppressive therapy. Effect of calcium and 1, 25(OH)2 vitamin D3 treatment. J Musculoskelet Neuronal Interact 3:71–76PubMed

12.

Winer KK, Ko CW, Reynolds JC, Dowdy K, Keil M, Peterson D, Gerber LH, McGarvey C, Cutler GB Jr (2003) Long-term treatment of hypoparathyroidism: a randomized controlled study comparing parathyroid hormone-(1–34) versus calcitriol and calcium. J Clin Endocrinol Metab 88:4214–4220PubMedCrossRef

13.

Fujiyama K, Kiriyama T, Ito M, Nakata K, Yamashita S, Yokoyama N, Nagataki S (1995) Attenuation of postmenopausal high turnover bone loss in patients with hypoparathyroidism. J Clin Endocrinol Metab 80:2135–2138PubMedCrossRef

14.

Mazokopakis EE, Starakis IK, Papadomanolaki MG, Batistakis AG, Papadakis JA (2006) Changes of bone mineral density in pre-menopausal women with differentiated thyroid cancer receiving L-thyroxine suppressive therapy. Curr Med Res Opin 22:1369–1373PubMedCrossRef

15.

Seeman E, Wahner HW, Offord KP, Kumar R, Johnson WJ, Riggs BL (1982) Differential effects of endocrine dysfunction on the axial and the appendicular skeleton. J Clin Invest 69:1302–1309PubMedCrossRef

16.

Murphy E, Gluer CC, Reid DM, Felsenberg D, Roux C, Eastell R, Williams GR (2010) Thyroid function within the upper normal range is associated with reduced bone mineral density and an increased risk of nonvertebral fractures in healthy euthyroid postmenopausal women. J Clin Endocrinol Metab 95:3173–3181PubMedCrossRef

17.

Rubin MR, Dempster DW, Zhou H, Shane E, Nickolas T, Sliney J Jr, Silverberg SJ, Bilezikian JP (2008) Dynamic and structural properties of the skeleton in hypoparathyroidism. J Bone Miner Res 23:2018–2024PubMedCrossRef

18.

Rubin MR, Sliney J Jr, McMahon DJ, Silverberg SJ, Bilezikian JP (2010) Therapy of hypoparathyroidism with intact parathyroid hormone. Osteoporos Int 21(11):1927–1934PubMedCrossRef

19.

Rubin MR, Bilezikian JP (2010) Hypoparathyroidism: clinical features, skeletal microstructure and parathyroid hormone replacement. Arq Bras Endocrinol Metabol 54:220–226PubMedCrossRef

Titel: Low bone turnover and increase of bone mineral density in a premenopausal woman with postoperative hypoparathyroidism and thyroxine suppressive therapy
verfasst von: K. Amrein
H. P. Dimai
H. Dobnig
A. Fahrleitner-Pammer
Publikationsdatum: 01.11.2011
Verlag: Springer-Verlag
Erschienen in: Osteoporosis International / Ausgabe 11/2011
Print ISSN: 0937-941X
Elektronische ISSN: 1433-2965
DOI: https://doi.org/10.1007/s00198-010-1441-9

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Low bone turnover and increase of bone mineral density in a premenopausal woman with postoperative hypoparathyroidism and thyroxine suppressive therapy

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