nach oben

Erschienen in:

12.01.2018 | Original Article

Low risk for hip fracture and high risk for hip arthroplasty due to osteoarthritis among Swedish farmers

verfasst von: H. Johansson, C. Hongslo Vala, A. Odén, M. Lorentzon, E. McCloskey, J. A. Kanis, N. C. Harvey, C. Ohlsson, L. Stefan Lohmander, J. Kärrholm, D. Mellström

Erschienen in: Osteoporosis International | Ausgabe 3/2018

Einloggen, um Zugang zu erhalten

Abstract

Summary

We aimed to study the risk of hip fracture and risk of hip arthroplasty among farmers in Sweden. Our results indicate that farming, representing an occupation with high physical activity, in men is associated with a lower risk of hip fracture but an increased risk of hip arthroplasty.

Introduction

The risks of hip fracture and hip arthroplasty are influenced by factors including socioeconomic status, education, urbanization, latitude of residence, and physical activity. Farming is an occupation encompassing rural living and high level of physical activity. Therefore, we aimed to study the risk of hip fracture and risk of hip arthroplasty among farmers in Sweden.

Methods

We studied the risk of hip fracture, and hip arthroplasty due to primary osteoarthritis, in all men and women aged 35 years or more in Sweden between 1987 and 2002. Documented occupations were available in 3.5 million individuals, of whom 97,136 were farmers. The effects of age, sex, income, education, location of residence, and occupation on risk of hip fracture or hip arthroplasty were examined using a modification of Poisson regression.

Results

A total of 4027 farmers and 93,109 individuals with other occupations sustained a hip fracture, while 5349 farmers and 63,473 others underwent a hip arthroplasty. Risk of hip fracture was higher with greater age, lower income, lower education, higher latitude, and urban area for all men and women. Compared to all other occupations, male farmers had a 20% lower age-adjusted risk of hip fracture (hazard ratio (HR) 0.80, 95%CI 0.77–0.84), an effect that was not seen in female farmers (HR 0.96, 95% CI 0.91–1.01). Both male and female farmers had a higher age-adjusted risk for hip arthroplasty.

Conclusions

Our results indicate that farming, representing an occupation with high physical activity, in men is associated with a lower risk of hip fracture but an increased risk of hip arthroplasty.

Litwic A, Edwards MH, Dennison EM, Cooper C (2013) Epidemiology and burden of osteoarthritis. Br Med Bull 105(1):185–199. https://doi.org/10.1093/bmb/lds038 CrossRefPubMedPubMedCentral

Global Burden of Disease Study C (2015) Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the global burden of disease study 2013. Lancet 386(9995):743–800. https://doi.org/10.1016/S0140-6736(15)60692-4 CrossRef

Harvey N, Dennison E, Cooper C (2013) The epidemiology of osteoporotic fractures. In: Primer on the metabolic bone diseases and disorders of mineral metabolism, 8th Edition. John Wiley & Sons, Inc., US, p 348–356

Oden A, Kanis JA, McCloskey EV, Johansson H (2014) The effect of latitude on the risk and seasonal variation in hip fracture in Sweden. J Bone Miner Res 29(10):2217–2223. https://doi.org/10.1002/jbmr.2250 CrossRefPubMed

Harris EC, Coggon D (2015) HIP osteoarthritis and work. Best Pract Res Clin Rheumatol 29(3):462–482. https://doi.org/10.1016/j.berh.2015.04.015 CrossRefPubMedPubMedCentral

Franklin J, Ingvarsson T, Englund M, Lohmander S (2010) Association between occupation and knee and hip replacement due to osteoarthritis: a case-control study. Arthritis Res Ther 12(3):R102. https://doi.org/10.1186/ar3033 CrossRefPubMedPubMedCentral

Andersen S, Thygesen LC, Davidsen M, Helweg-Larsen K (2012) Cumulative years in occupation and the risk of hip or knee osteoarthritis in men and women: a register-based follow-up study. Occup Environ Med 69(5):325–330. https://doi.org/10.1136/oemed-2011-100033 CrossRefPubMed

Thelin A, Holmberg S (2007) Hip osteoarthritis in a rural male population: a prospective population-based register study. Am J Ind Med 50(8):604–607. https://doi.org/10.1002/ajim.20484 CrossRefPubMed

Thelin A, Vingard E, Holmberg S (2004) Osteoarthritis of the hip joint and farm work. Am J Ind Med 45(2):202–209. https://doi.org/10.1002/ajim.10330 CrossRefPubMed

10.

Jensen LK (2008) Hip osteoarthritis: influence of work with heavy lifting, climbing stairs or ladders, or combining kneeling/squatting with heavy lifting. Occup Environ Med 65(1):6–19. https://doi.org/10.1136/oem.2006.032409 CrossRefPubMed

11.

Walker-Bone K, Palmer KT (2002) Musculoskeletal disorders in farmers and farm workers. Occup Med (Lond) 52(8):441–450. https://doi.org/10.1093/occmed/52.8.441 CrossRef

12.

Palumbo AJ, Michael YL, Burstyn I, Lee BK, Wallace R (2015) Occupational physical demand and risk of hip fracture in older women. Occup Environ Med 72(8):567–572. https://doi.org/10.1136/oemed-2014-102670 CrossRefPubMed

13.

Daly RM, Ahlborg HG, Ringsberg K, Gardsell P, Sernbo I, Karlsson MK (2008) Association between changes in habitual physical activity and changes in bone density, muscle strength, and functional performance in elderly men and women. J Am Geriatr Soc 56(12):2252–2260. https://doi.org/10.1111/j.1532-5415.2008.02039.x CrossRefPubMed

14.

Englund U, Nordstrom P, Nilsson J, Bucht G, Bjornstig U, Hallmans G, Svensson O, Pettersson U (2011) Physical activity in middle-aged women and hip fracture risk: the UFO study. Osteoporos Int 22(2):499–505. https://doi.org/10.1007/s00198-010-1234-1 CrossRefPubMed

15.

Farahmand BY, Persson PG, Michaelsson K, Baron JA, Alberts A, Moradi T, Ljunghall S (2000) Physical activity and hip fracture: a population-based case-control study. Swedish hip fracture study group. Int J Epidemiol 29(2):308–314. https://doi.org/10.1093/ije/29.2.308 CrossRefPubMed

16.

Joakimsen RM, Fonnebo V, Magnus JH, Stormer J, Tollan A, Sogaard AJ (1998) The Tromso study: physical activity and the incidence of fractures in a middle-aged population. J Bone Miner Res 13(7):1149–1157. https://doi.org/10.1359/jbmr.1998.13.7.1149 CrossRefPubMed

17.

Cumming RG, Klineberg RJ (1994) Case-control study of risk factors for hip fractures in the elderly. Am J Epidemiol 139(5):493–503. https://doi.org/10.1093/oxfordjournals.aje.a117032 CrossRefPubMed

18.

Cooper C, Wickham C, Coggon D (1990) Sedentary work in middle life and fracture of the proximal femur. Br J Ind Med 47(1):69–70PubMedPubMedCentral

19.

Jaglal SB, Kreiger N, Darlington GA (1995) Lifetime occupational physical activity and risk of hip fracture in women. Ann Epidemiol 5(4):321–324. https://doi.org/10.1016/1047-2797(94)00100-8 CrossRefPubMed

20.

Meyer HE, Tverdal A, Falch JA (1993) Risk factors for hip fracture in middle-aged Norwegian women and men. Am J Epidemiol 137(11):1203–1211. https://doi.org/10.1093/oxfordjournals.aje.a116622 CrossRefPubMed

21.

Johnell O, Gullberg B, Kanis JA, Allander E, Elffors L, Dequeker J, Dilsen G, Gennari C, Lopes Vaz A, Lyritis G et al (1995) Risk factors for hip fracture in European women: the MEDOS study. Mediterranean osteoporosis study. J Bone Miner Res 10(11):1802–1815. https://doi.org/10.1002/jbmr.5650101125 CrossRefPubMed

22.

Suen LK (1998) Occupation and risk of hip fracture. J Public Health Med 20(4):428–433. https://doi.org/10.1093/oxfordjournals.pubmed.a024798 CrossRefPubMed

23.

Appleby PN, Allen NE, Roddam AW, Key TJ (2008) Physical activity and fracture risk: a prospective study of 1898 incident fractures among 34,696 British men and women. J Bone Miner Metab 26(2):191–198. https://doi.org/10.1007/s00774-007-0806-4 CrossRefPubMed

24.

Trimpou P, Landin-Wilhelmsen K, Oden A, Rosengren A, Wilhelmsen L (2010) Male risk factors for hip fracture-a 30-year follow-up study in 7,495 men. Osteoporos Int 21(3):409–416. https://doi.org/10.1007/s00198-009-0961-7 CrossRefPubMed

25.

Franklin J, Englund M, Ingvarsson T, Lohmander S (2010) The association between hip fracture and hip osteoarthritis: a case-control study. BMC Musculoskelet Disord 11(1):274. https://doi.org/10.1186/1471-2474-11-274 CrossRefPubMedPubMedCentral

26.

Johansson H, Kanis JA, Oden A, McCloskey E, Chapurlat RD, Christiansen C, Cummings SR, Diez-Perez A, Eisman JA, Fujiwara S, Gluer CC, Goltzman D, Hans D, Khaw KT, Krieg MA, Kroger H, LaCroix AZ, Lau E, Leslie WD, Mellstrom D, Melton LJ 3rd, O'Neill TW, Pasco JA, Prior JC, Reid DM, Rivadeneira F, van Staa T, Yoshimura N, Zillikens MC (2014) A meta-analysis of the association of fracture risk and body mass index in women. J Bone Miner Res 29(1):223–233. https://doi.org/10.1002/jbmr.2017 CrossRefPubMed

27.

De Laet C, Kanis JA, Oden A, Johanson H, Johnell O, Delmas P, Eisman JA, Kroger H, Fujiwara S, Garnero P, McCloskey EV, Mellstrom D, Melton LJ 3rd, Meunier PJ, Pols HA, Reeve J, Silman A, Tenenhouse A (2005) Body mass index as a predictor of fracture risk: a meta-analysis. Osteoporos Int 16(11):1330–1338. https://doi.org/10.1007/s00198-005-1863-y CrossRefPubMed

28.

Kanis JA, Johnell O, De Laet C, Johansson H, Oden A, Delmas P, Eisman J, Fujiwara S, Garnero P, Kroger H, McCloskey EV, Mellstrom D, Melton LJ, Pols H, Reeve J, Silman A, Tenenhouse A (2004) A meta-analysis of previous fracture and subsequent fracture risk. Bone 35(2):375–382. https://doi.org/10.1016/j.bone.2004.03.024 CrossRefPubMed

29.

Kanis JA, Johnell O, Oden A, Johansson H, De Laet C, Eisman JA, Fujiwara S, Kroger H, McCloskey EV, Mellstrom D, Melton LJ, Pols H, Reeve J, Silman A, Tenenhouse A (2005) Smoking and fracture risk: a meta-analysis. Osteoporos Int 16(2):155–162. https://doi.org/10.1007/s00198-004-1640-3 CrossRefPubMed

30.

Kanis JA, Johansson H, Johnell O, Oden A, De Laet C, Eisman JA, Pols H, Tenenhouse A (2005) Alcohol intake as a risk factor for fracture. Osteoporos Int 16(7):737–742. https://doi.org/10.1007/s00198-004-1734-y CrossRefPubMed

31.

Johnell O, Borgstrom F, Jonsson B, Kanis J (2007) Latitude, socioeconomic prosperity, mobile phones and hip fracture risk. Osteoporos Int 18(3):333–337. https://doi.org/10.1007/s00198-006-0245-4 CrossRefPubMed

32.

Ludvigsson JF, Andersson E, Ekbom A, Feychting M, Kim JL, Reuterwall C, Heurgren M, Olausson PO (2011) External review and validation of the Swedish national inpatient register. BMC Public Health 11:450. https://doi.org/10.1186/1471-2458-11-450 CrossRefPubMedPubMedCentral

33.

Pouwels S, van Staa TP, Egberts AC, Leufkens HG, Cooper C, de Vries F (2009) Antipsychotic use and the risk of hip/femur fracture: a population-based case-control study. Osteoporos Int 20(9):1499–1506. https://doi.org/10.1007/s00198-008-0826-5 CrossRefPubMedPubMedCentral

34.

Breslow NE, Day NE (1987) Statistical methods in cancer research. IARC scientific publications no 82, volume II, p 131–135, International Agency for Research on Cancer, Lyon, France

35.

Vardavas CI, Linardakis MK, Hatzis CM, Saris WH, Kafatos AG (2009) Prevalence of obesity and physical inactivity among farmers from Crete (Greece), four decades after the seven countries study. Nutr Metab Cardiovasc Dis 19(3):156–162. https://doi.org/10.1016/j.numecd.2008.10.008 CrossRefPubMed

36.

Flugsrud GB, Nordsletten L, Espehaug B, Havelin LI, Meyer HE (2002) Risk factors for total hip replacement due to primary osteoarthritis: a cohort study in 50,034 persons. Arthritis Rheum 46(3):675–682. https://doi.org/10.1002/art.10115 CrossRefPubMed

37.

Hagglund G, Hansson LI, Ordeberg G (1984) Epidemiology of slipped capital femoral epiphysis in southern Sweden. Clin Orthop Relat Res 191:82–94

38.

Goodman DA, Feighan JE, Smith AD, Latimer B, Buly RL, Cooperman DR (1997) Subclinical slipped capital femoral epiphysis. Relationship to osteoarthrosis of the hip. J Bone Joint Surg Am 79(10):1489–1497. https://doi.org/10.2106/00004623-199710000-00005 CrossRefPubMed

39.

Kanis J, Johnell O, Gullberg B, Allander E, Elffors L, Ranstam J, Dequeker J, Dilsen G, Gennari C, Vaz AL, Lyritis G, Mazzuoli G, Miravet L, Passeri M, Perez Cano R, Rapado A, Ribot C (1999) Risk factors for hip fracture in men from southern Europe: the MEDOS study. Mediterranean osteoporosis study. Osteoporos Int 9(1):45–54. https://doi.org/10.1007/s001980050115 CrossRefPubMed

40.

Momose Y, Suenaga T (2015) Gender differences in the occurrence of nonfatalagricultural injuries among farmers in Fukuoka, Japan. J Rural Med 10(2):57–64. https://doi.org/10.2185/jrm.2897 CrossRefPubMedPubMedCentral

41.

Sandmark H, Hogstedt C, Vingard E (2000) Primary osteoarthrosis of the knee in men and women as a result of lifelong physical load from work. Scand J Work Environ Health 26(1):20–25. https://doi.org/10.5271/sjweh.505 CrossRefPubMed

42.

Holmberg S, Thelin A, Thelin N (2004) Is there an increased risk of knee osteoarthritis among farmers? A population-based case-control study. Int Arch Occup Environ Health 77(5):345–350. https://doi.org/10.1007/s00420-004-0518-1 CrossRefPubMed

43.

Lievense A, Bierma-Zeinstra S, Verhagen A, Verhaar J, Koes B (2001) Influence of work on the development of osteoarthritis of the hip: a systematic review. J Rheumatol 28(11):2520–2528PubMed

44.

Tuchsen F, Hannerz H, Jensen MV, Krause N (2003) Socioeconomic status, occupation, and risk of hospitalisation due to coxarthrosis in Denmark 1981-99. Ann Rheum Dis 62(11):1100–1105. https://doi.org/10.1136/ard.62.11.1100 CrossRefPubMedPubMedCentral

45.

Food and Agriculture Organization (FAO) of the United Nations (2011) The state of food and agriculture. Women in Agriculture: closing the gender gap for development. FAO, Rome

46.

Kanis JA, Oden A, McCloskey EV, Johansson H, Wahl DA, Cooper C, Epidemiology IOFWGo, Quality of L (2012) A systematic review of hip fracture incidence and probability of fracture worldwide. Osteoporos Int 23(9):2239–2256. https://doi.org/10.1007/s00198-012-1964-3 CrossRefPubMedPubMedCentral

47.

Mannius S, Mellstrom D, Oden A, Rundgren A, Zetterberg C (1987) Incidence of hip fracture in western Sweden 1974-1982. Comparison of rural and urban populations. Acta Orthop Scand 58(1):38–42. https://doi.org/10.3109/17453678709146340 CrossRefPubMed

48.

Pickett W, King N, Lawson J, Dosman JA, Trask C, Brison RJ, Hagel L, Janssen I, Saskatchewan Farm Injury Cohort Study T (2015) Farmers, mechanized work, and links to obesity. Prev Med 70:59–63. https://doi.org/10.1016/j.ypmed.2014.11.012 CrossRefPubMed

Titel: Low risk for hip fracture and high risk for hip arthroplasty due to osteoarthritis among Swedish farmers
verfasst von: H. Johansson
C. Hongslo Vala
A. Odén
M. Lorentzon
E. McCloskey
J. A. Kanis
N. C. Harvey
C. Ohlsson
L. Stefan Lohmander
J. Kärrholm
D. Mellström
Publikationsdatum: 12.01.2018
Verlag: Springer London
Erschienen in: Osteoporosis International / Ausgabe 3/2018
Print ISSN: 0937-941X
Elektronische ISSN: 1433-2965
DOI: https://doi.org/10.1007/s00198-017-4355-y

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen.
» Jetzt entdecken

Neu im Fachgebiet Orthopädie und Unfallchirurgie

Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

26.04.2024 Hüft-TEP Nachrichten

Ob bei einer Notfalloperation nach Schenkelhalsfraktur eine Hemiarthroplastik oder eine totale Endoprothese (TEP) eingebaut wird, sollte nicht allein vom Alter der Patientinnen und Patienten abhängen. Auch über 90-Jährige können von der TEP profitieren.

Arthroskopie kann Knieprothese nicht hinauszögern

25.04.2024 Gonarthrose Nachrichten

Ein arthroskopischer Eingriff bei Kniearthrose macht im Hinblick darauf, ob und wann ein Gelenkersatz fällig wird, offenbar keinen Unterschied.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Ärztliche Empathie hilft gegen Rückenschmerzen

23.04.2024 Leitsymptom Rückenschmerzen Nachrichten

Personen mit chronischen Rückenschmerzen, die von einfühlsamen Ärzten und Ärztinnen betreut werden, berichten über weniger Beschwerden und eine bessere Lebensqualität.

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Springer Medizin

Abstract

Summary

Introduction

Methods

Results

Conclusions

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 3/2018

Interpretation of milk research results: response to comments by Michaelsson and Byberg

Trabecular bone quality is lower in adults with type 1 diabetes and is negatively associated with insulin resistance

Early diagnosis of osteoporosis using radiogrammetry and texture analysis from hand and wrist radiographs in Indian population

Restrictive pulmonary dysfunction is associated with vertebral fractures and bone loss in elderly postmenopausal women

Insights into the bisphosphonate holiday: a preliminary FTIRI study