The online version of this article (doi:10.1186/1752-1947-6-416) contains supplementary material, which is available to authorized users.
The authors declare that they have no competing interests in the preparation of this article.
DM, collection of data, manuscript preparation; AJ, collection of data, manuscript preparation; MP, manuscript preparation, analysis; SK, manuscript preparation, analysis. SK was the major contributor to writing the manuscript. All authors read and approved the final manuscript.
Lymphoepithelial carcinoma of the maxillary sinus is a very rare malignancy and it can be difficult to make a pre-operative diagnosis.
A 72-year-old Caucasian woman presented to our facility with an isolated right-side epistaxis that had been present for three months, with the results of a computed tomography scan showing a soft tissue mass in the right maxillary sinus with an impacted tooth. The results of a transnasal endoscopic biopsy were compatible with a lymphoepithelial carcinoma, following which our patient underwent a radical excision of the mass. The final histology results revealed lymphoepithelial carcinoma of the maxillary sinus with negative assays for Epstein-Barr virus. Our patient was given post-operative external radiotherapy and has remained disease-free at three-year follow-up.
This report details the diagnosis and management of a case of lymphoepithelial carcinoma of the maxillary sinus, which is a very rare malignant tumor with very little mention in the literature. Only a strong suspicion with systematic use of various patho-immunological tests helps to arrive at a definitive diagnosis by excluding other better-known tumors.
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- Lymphoepithelial carcinoma in the maxillary sinus: a case report
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