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Current Neurology and Neuroscience Reports

Erschienen in:

27.12.2023 | Review

Magnetoencephalography for Epilepsy Presurgical Evaluation

verfasst von: Aaron S. Geller, Peter Teale, Eugene Kronberg, John S. Ebersole

Erschienen in: Current Neurology and Neuroscience Reports | Ausgabe 2/2024

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Abstract

Purpose of the Review

Magnetoencephalography (MEG) is a functional neuroimaging technique that records neurophysiology data with millisecond temporal resolution and localizes it with subcentimeter accuracy. Its capability to provide high resolution in both of these domains makes it a powerful tool both in basic neuroscience as well as clinical applications. In neurology, it has proven useful in its ability to record and localize epileptiform activity. Epilepsy workup typically begins with scalp electroencephalography (EEG), but in many situations, EEG-based localization of the epileptogenic zone is inadequate. The complementary sensitivity of MEG can be crucial in such cases, and MEG has been adopted at many centers as an important resource in building a surgical hypothesis. In this paper, we review recent work evaluating the extent of MEG influence of presurgical evaluations, novel analyses of MEG data employed in surgical workup, and new MEG instrumentation that will likely affect the field of clinical MEG.

Recent Findings

MEG consistently contributes to presurgical evaluation and these contributions often change the plan for epilepsy surgery. Extensive work has been done to develop new analytic methods for localizing the source of epileptiform activity with MEG. Systems using optically pumped magnetometry (OPM) have been successfully deployed to record and localize epileptiform activity.

Summary

MEG remains an important noninvasive tool for epilepsy presurgical evaluation. Continued improvements in analytic methodology will likely increase the diagnostic yield of the test. Novel instrumentation with OPM may contribute to this as well, and may increase accessibility of MEG by decreasing cost.

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Titel: Magnetoencephalography for Epilepsy Presurgical Evaluation
verfasst von: Aaron S. Geller
Peter Teale
Eugene Kronberg
John S. Ebersole
Publikationsdatum: 27.12.2023
Verlag: Springer US
Erschienen in: Current Neurology and Neuroscience Reports / Ausgabe 2/2024
Print ISSN: 1528-4042
Elektronische ISSN: 1534-6293
DOI: https://doi.org/10.1007/s11910-023-01328-5

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