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Current Gastroenterology Reports

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01.02.2016 | Liver (S Cotler and E Kallwitz, Section Editors)

Management of Difficult Cases of Autoimmune Hepatitis

verfasst von: Craig Lammert, Veronica M. Loy, Kiyoko Oshima, Samer Gawrieh

Erschienen in: Current Gastroenterology Reports | Ausgabe 2/2016

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Abstract

Autoimmune hepatitis (AIH) is a complex autoimmune disease characterized by immune-mediated destruction of hepatic parenchyma which can result in cirrhosis, liver failure, and death. Current American Association for the Study of Liver Diseases (AASLD) and European Association for the Study of Liver (EASL) guidelines recommend corticosteroids alone or in combination with azathioprine as first-line treatment strategies. However, a significant proportion of patients may not be able to tolerate or achieve complete biochemical response with these options. In this article, we discuss approaches to these patients and other challenging AIH patient groups such as the asymptomatic, pregnant, elderly, and liver transplant recipients.

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Titel: Management of Difficult Cases of Autoimmune Hepatitis
verfasst von: Craig Lammert
Veronica M. Loy
Kiyoko Oshima
Samer Gawrieh
Publikationsdatum: 01.02.2016
Verlag: Springer US
Erschienen in: Current Gastroenterology Reports / Ausgabe 2/2016
Print ISSN: 1522-8037
Elektronische ISSN: 1534-312X
DOI: https://doi.org/10.1007/s11894-015-0484-7

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