Skip to main content
Erschienen in: Supportive Care in Cancer 7/2023

01.07.2023 | Research

Medication self-management behaviors of adolescents and young adults with cancer

verfasst von: Jeanne M. Erickson, Anna Kamke-Jordan, Ilissa Jasmine Lancaster, Akasha Palou-Torres, Marloe Esch, Alyssa Gonzalez, John Charlson, Kristin Bingen

Erschienen in: Supportive Care in Cancer | Ausgabe 7/2023

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Adolescents and young adults (AYAs) with cancer are challenged to manage complex medication regimens during treatment. The aims of the study are to (1) describe the medication self-management behaviors of AYAs with cancer and (2) examine the barriers and facilitators to AYAs’ optimal use of medications, including their self-efficacy to manage medications.

Methods

This cross-sectional study enrolled 30 AYAs (18–29 years) with cancer who were receiving chemotherapy. Participants electronically completed a demographic form, a health literacy screen, and the PROMIS Self-efficacy for Medication Management instrument. They completed a semi-structured interview to answer questions about their medication self-management behaviors.

Results

Participants (53% female, mean age = 21.9 y) had a variety of AYA cancer diagnoses. Over half (63%) had limited health literacy. Most AYAs had accurate knowledge about their medications and average self-efficacy for managing medications. These AYAs were managing an average of 6 scheduled and 3 unscheduled medications. Oral chemotherapy was prescribed for 13 AYAs; other medications were for prevention of complications and symptom management. Many AYAs relied on a parent for obtaining and paying for medications, used multiple reminders to take medications, and used a variety of strategies to store and organize medications.

Conclusion

AYAs with cancer were knowledgeable and confident about managing complex medication regimens but needed support and reminders. Providers should review medication-taking strategies with AYAs and ensure a support person is available.
Literatur
2.
Zurück zum Zitat Ryan P, Sawin KJ (2009) The Individual and Family Self-Management Theory: background and perspectives on context, process, and outcomes. Nurs Outlook 57:217-225 e216CrossRefPubMedPubMedCentral Ryan P, Sawin KJ (2009) The Individual and Family Self-Management Theory: background and perspectives on context, process, and outcomes. Nurs Outlook 57:217-225 e216CrossRefPubMedPubMedCentral
3.
Zurück zum Zitat Linder LA, Erickson JM, Stegenga K, Macpherson CF, Wawrzynski S, Wilson C, Ameringer S (2017) Symptom self-management strategies reported by adolescents and young adults with cancer receiving chemotherapy. Support Care Cancer 25:3793–3806CrossRefPubMed Linder LA, Erickson JM, Stegenga K, Macpherson CF, Wawrzynski S, Wilson C, Ameringer S (2017) Symptom self-management strategies reported by adolescents and young adults with cancer receiving chemotherapy. Support Care Cancer 25:3793–3806CrossRefPubMed
4.
Zurück zum Zitat Thornton CP, Li M, Yeh CH, Ruble K (2021) Self-efficacy in symptom management for adolescents and young adults with cancer: a systematic review. Support Care Cancer 29:2851–2862CrossRefPubMed Thornton CP, Li M, Yeh CH, Ruble K (2021) Self-efficacy in symptom management for adolescents and young adults with cancer: a systematic review. Support Care Cancer 29:2851–2862CrossRefPubMed
5.
Zurück zum Zitat Bhatia S, Landier W, Hageman L, Kim H, Chen Y, Crews KR, Evans WE, Bostrom B, Casillas J, Dickens DS, Maloney KW, Neglia JP, Ravindranath Y, Ritchey AK, Wong FL, Relling MV (2014) 6MP adherence in a multiracial cohort of children with acute lymphoblastic leukemia: a Children’s Oncology Group study. Blood 124:2345–2353CrossRefPubMedPubMedCentral Bhatia S, Landier W, Hageman L, Kim H, Chen Y, Crews KR, Evans WE, Bostrom B, Casillas J, Dickens DS, Maloney KW, Neglia JP, Ravindranath Y, Ritchey AK, Wong FL, Relling MV (2014) 6MP adherence in a multiracial cohort of children with acute lymphoblastic leukemia: a Children’s Oncology Group study. Blood 124:2345–2353CrossRefPubMedPubMedCentral
6.
Zurück zum Zitat McGrady ME, Williams SN, Davies SM, Pai AL (2014) Adherence to outpatient oral medication regimens in adolescent hematopoietic stem cell transplant recipients. Eur J Oncol Nurs 18:140–144CrossRefPubMed McGrady ME, Williams SN, Davies SM, Pai AL (2014) Adherence to outpatient oral medication regimens in adolescent hematopoietic stem cell transplant recipients. Eur J Oncol Nurs 18:140–144CrossRefPubMed
7.
Zurück zum Zitat McGrady ME, Pai ALH (2019) A systematic review of rates, outcomes, and predictors of medication non-adherence among adolescents and young adults with cancer. J Adolesc Young Adult Oncol 8:485–494CrossRefPubMedPubMedCentral McGrady ME, Pai ALH (2019) A systematic review of rates, outcomes, and predictors of medication non-adherence among adolescents and young adults with cancer. J Adolesc Young Adult Oncol 8:485–494CrossRefPubMedPubMedCentral
8.
Zurück zum Zitat Rohan JM, Drotar D, Alderfer M, Donewar CW, Ewing L, Katz ER, Muriel A (2015) Electronic monitoring of medication adherence in early maintenance phase treatment for pediatric leukemia and lymphoma: identifying patterns of nonadherence. J Pediatr Psychol 40:75–84CrossRefPubMed Rohan JM, Drotar D, Alderfer M, Donewar CW, Ewing L, Katz ER, Muriel A (2015) Electronic monitoring of medication adherence in early maintenance phase treatment for pediatric leukemia and lymphoma: identifying patterns of nonadherence. J Pediatr Psychol 40:75–84CrossRefPubMed
9.
Zurück zum Zitat Bhatia S, Landier W, Shangguan M, Hageman L, Schaible AN, Carter AR, Hanby CL, Leisenring W, Yasui Y, Kornegay NM, Mascarenhas L, Ritchey AK, Casillas JN, Dickens DS, Meza J, Carroll WL, Relling MV, Wong FL (2012) Nonadherence to oral mercaptopurine and risk of relapse in Hispanic and non-Hispanic white children with acute lymphoblastic leukemia: a report from the children’s oncology group. J Clin Oncol 30:2094–2101CrossRefPubMedPubMedCentral Bhatia S, Landier W, Shangguan M, Hageman L, Schaible AN, Carter AR, Hanby CL, Leisenring W, Yasui Y, Kornegay NM, Mascarenhas L, Ritchey AK, Casillas JN, Dickens DS, Meza J, Carroll WL, Relling MV, Wong FL (2012) Nonadherence to oral mercaptopurine and risk of relapse in Hispanic and non-Hispanic white children with acute lymphoblastic leukemia: a report from the children’s oncology group. J Clin Oncol 30:2094–2101CrossRefPubMedPubMedCentral
10.
Zurück zum Zitat Kaul S, Avila JC, Mehta HB, Rodriguez AM, Kuo YF, Kirchhoff AC (2017) Cost-related medication nonadherence among adolescent and young adult cancer survivors. Cancer 123:2726–2734CrossRefPubMed Kaul S, Avila JC, Mehta HB, Rodriguez AM, Kuo YF, Kirchhoff AC (2017) Cost-related medication nonadherence among adolescent and young adult cancer survivors. Cancer 123:2726–2734CrossRefPubMed
11.
Zurück zum Zitat Wu YP, Linder LA, Kanokvimankul P, Fowler B, Parsons BG, Macpherson CF, Johnson RH (2018) Use of a smartphone application for prompting oral medication adherence among adolescents and young adults with cancer. Oncol Nurs Forum 45:69–76CrossRefPubMedPubMedCentral Wu YP, Linder LA, Kanokvimankul P, Fowler B, Parsons BG, Macpherson CF, Johnson RH (2018) Use of a smartphone application for prompting oral medication adherence among adolescents and young adults with cancer. Oncol Nurs Forum 45:69–76CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat Bailey SC, Oramasionwu CU, Wolf MS (2013) Rethinking adherence: a health literacy-informed model of medication self-management. J Health Commun 18(Suppl 1):20–30CrossRefPubMedPubMedCentral Bailey SC, Oramasionwu CU, Wolf MS (2013) Rethinking adherence: a health literacy-informed model of medication self-management. J Health Commun 18(Suppl 1):20–30CrossRefPubMedPubMedCentral
13.
Zurück zum Zitat McGrady ME, Brown GA, Pai AL (2016) Medication adherence decision-making among adolescents and young adults with cancer. Eur J Oncol Nurs 20:207–214CrossRefPubMed McGrady ME, Brown GA, Pai AL (2016) Medication adherence decision-making among adolescents and young adults with cancer. Eur J Oncol Nurs 20:207–214CrossRefPubMed
14.
Zurück zum Zitat Arnett JJ (2000) Emerging adulthood A theory of development from the late teens through the twenties. Am Psychol 55:469–480CrossRefPubMed Arnett JJ (2000) Emerging adulthood A theory of development from the late teens through the twenties. Am Psychol 55:469–480CrossRefPubMed
15.
Zurück zum Zitat Betz CL, Lobo ML, Nehring WM, Bui K (2013) Voices not heard: a systematic review of adolescents’ and emerging adults’ perspectives of health care transition. Nurs Outlook 61:311–336CrossRefPubMed Betz CL, Lobo ML, Nehring WM, Bui K (2013) Voices not heard: a systematic review of adolescents’ and emerging adults’ perspectives of health care transition. Nurs Outlook 61:311–336CrossRefPubMed
16.
Zurück zum Zitat Matud MP, Diaz A, Bethencourt JM, Ibanez I (2020) Stress and psychological distress in emerging adulthood: a gender analysis. J Clin Med 9 Matud MP, Diaz A, Bethencourt JM, Ibanez I (2020) Stress and psychological distress in emerging adulthood: a gender analysis. J Clin Med 9
17.
Zurück zum Zitat Chew LD, Griffin JM, Partin MR, Noorbaloochi S, Grill JP, Snyder A, Bradley KA, Nugent SM, Baines AD, Vanryn M (2008) Validation of screening questions for limited health literacy in a large VA outpatient population. J Gen Intern Med 23:561–566CrossRefPubMedPubMedCentral Chew LD, Griffin JM, Partin MR, Noorbaloochi S, Grill JP, Snyder A, Bradley KA, Nugent SM, Baines AD, Vanryn M (2008) Validation of screening questions for limited health literacy in a large VA outpatient population. J Gen Intern Med 23:561–566CrossRefPubMedPubMedCentral
18.
Zurück zum Zitat Chew LD, Bradley KA, Boyko EJ (2004) Brief questions to identify patients with inadequate health literacy. Fam Med 36:588–594PubMed Chew LD, Bradley KA, Boyko EJ (2004) Brief questions to identify patients with inadequate health literacy. Fam Med 36:588–594PubMed
19.
Zurück zum Zitat Gruber-Baldini AL, Velozo C, Romero S, Shulman LM (2017) Validation of the PROMIS((R)) measures of self-efficacy for managing chronic conditions. Qual Life Res 26:1915–1924CrossRefPubMedPubMedCentral Gruber-Baldini AL, Velozo C, Romero S, Shulman LM (2017) Validation of the PROMIS((R)) measures of self-efficacy for managing chronic conditions. Qual Life Res 26:1915–1924CrossRefPubMedPubMedCentral
20.
Zurück zum Zitat Murphy SL, Berrocal VJ, Poole JL, Khanna D (2022) Reliability, validity, and responsiveness to change of the Patient-Reported Outcomes Measurement Information System self-efficacy for managing chronic conditions measure in systemic sclerosis. J Scleroderma Relat Disord 7:110–116CrossRefPubMed Murphy SL, Berrocal VJ, Poole JL, Khanna D (2022) Reliability, validity, and responsiveness to change of the Patient-Reported Outcomes Measurement Information System self-efficacy for managing chronic conditions measure in systemic sclerosis. J Scleroderma Relat Disord 7:110–116CrossRefPubMed
21.
Zurück zum Zitat Sawin KJ, Heffelfinger A, Cashin SE, Brei TJ (2018) The development of the adolescent/young adult self-management and independence scale II: psychometric data. J Pediatr Rehabil Med 11:311–322CrossRefPubMed Sawin KJ, Heffelfinger A, Cashin SE, Brei TJ (2018) The development of the adolescent/young adult self-management and independence scale II: psychometric data. J Pediatr Rehabil Med 11:311–322CrossRefPubMed
22.
Zurück zum Zitat Betts AC, Murphy CC, Shay LA, Balasubramanian BA, Markham C, Roth ME, Allicock M (2022) Polypharmacy and medication fill nonadherence in a population-based sample of adolescent and young adult cancer survivors. J Cancer Surviv 2008–2017 Betts AC, Murphy CC, Shay LA, Balasubramanian BA, Markham C, Roth ME, Allicock M (2022) Polypharmacy and medication fill nonadherence in a population-based sample of adolescent and young adult cancer survivors. J Cancer Surviv 2008–2017
23.
Zurück zum Zitat Bandura A (1977) Self-efficacy: toward a unifying theory of behavioral change. Psychol Rev 84:191–215CrossRefPubMed Bandura A (1977) Self-efficacy: toward a unifying theory of behavioral change. Psychol Rev 84:191–215CrossRefPubMed
24.
Zurück zum Zitat Herts KL, Khaled MM, Stanton AL (2017) Correlates of self-efficacy for disease management in adolescent/young adult cancer survivors: a systematic review. Health Psychol 36:192–205CrossRefPubMed Herts KL, Khaled MM, Stanton AL (2017) Correlates of self-efficacy for disease management in adolescent/young adult cancer survivors: a systematic review. Health Psychol 36:192–205CrossRefPubMed
25.
Zurück zum Zitat Kato PM, Cole SW, Bradlyn AS, Pollock BH (2008) A video game improves behavioral outcomes in adolescents and young adults with cancer: a randomized trial. Pediatrics 122:e305-317CrossRefPubMed Kato PM, Cole SW, Bradlyn AS, Pollock BH (2008) A video game improves behavioral outcomes in adolescents and young adults with cancer: a randomized trial. Pediatrics 122:e305-317CrossRefPubMed
26.
Zurück zum Zitat Santana S, Brach C, Harris L, Ochiai E, Blakey C, Bevington F, Kleinman D, Pronk N (2021) Updating health literacy for healthy people 2030: defining its importance for a new decade in public health. J Public Health Manag Pract 27:S258–S264CrossRefPubMedPubMedCentral Santana S, Brach C, Harris L, Ochiai E, Blakey C, Bevington F, Kleinman D, Pronk N (2021) Updating health literacy for healthy people 2030: defining its importance for a new decade in public health. J Public Health Manag Pract 27:S258–S264CrossRefPubMedPubMedCentral
27.
Zurück zum Zitat Neter E, Brainin E (2019) Association between health literacy, ehealth literacy, and health outcomes among patients with long-term conditions European Psychologist Neter E, Brainin E (2019) Association between health literacy, ehealth literacy, and health outcomes among patients with long-term conditions European Psychologist
28.
Zurück zum Zitat Psihogios AM, Schwartz LA, Ewing KB, Czerniecki B, Kersun LS, Pai ALH, Deatrick JA, Barakat LP (2020) Adherence to multiple treatment recommendations in adolescents and young adults with cancer: a mixed methods, multi-informant investigation. J Adolesc Young Adult Oncol 9:651–661CrossRefPubMedPubMedCentral Psihogios AM, Schwartz LA, Ewing KB, Czerniecki B, Kersun LS, Pai ALH, Deatrick JA, Barakat LP (2020) Adherence to multiple treatment recommendations in adolescents and young adults with cancer: a mixed methods, multi-informant investigation. J Adolesc Young Adult Oncol 9:651–661CrossRefPubMedPubMedCentral
29.
Zurück zum Zitat McGrady ME, Ketterl TG, Norris RE, Perentesis JP, Pettee D, Mara CA, Breen G, Pai ALH (2023) Barriers to medication adherence among adolescents and young adults with cancer. Pediatr Blood Cancer 70:e30186CrossRefPubMed McGrady ME, Ketterl TG, Norris RE, Perentesis JP, Pettee D, Mara CA, Breen G, Pai ALH (2023) Barriers to medication adherence among adolescents and young adults with cancer. Pediatr Blood Cancer 70:e30186CrossRefPubMed
Metadaten
Titel
Medication self-management behaviors of adolescents and young adults with cancer
verfasst von
Jeanne M. Erickson
Anna Kamke-Jordan
Ilissa Jasmine Lancaster
Akasha Palou-Torres
Marloe Esch
Alyssa Gonzalez
John Charlson
Kristin Bingen
Publikationsdatum
01.07.2023
Verlag
Springer Berlin Heidelberg
Erschienen in
Supportive Care in Cancer / Ausgabe 7/2023
Print ISSN: 0941-4355
Elektronische ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-023-07863-8

Weitere Artikel der Ausgabe 7/2023

Supportive Care in Cancer 7/2023 Zur Ausgabe

Erhöhte Mortalität bei postpartalem Brustkrebs

07.05.2024 Mammakarzinom Nachrichten

Auch für Trägerinnen von BRCA-Varianten gilt: Erkranken sie fünf bis zehn Jahre nach der letzten Schwangerschaft an Brustkrebs, ist das Sterberisiko besonders hoch.

Hypertherme Chemotherapie bietet Chance auf Blasenerhalt

07.05.2024 Harnblasenkarzinom Nachrichten

Eine hypertherme intravesikale Chemotherapie mit Mitomycin kann für Patienten mit hochriskantem nicht muskelinvasivem Blasenkrebs eine Alternative zur radikalen Zystektomie darstellen. Kölner Urologen berichten über ihre Erfahrungen.

Ein Drittel der jungen Ärztinnen und Ärzte erwägt abzuwandern

07.05.2024 Medizinstudium Nachrichten

Extreme Arbeitsverdichtung und kaum Supervision: Dr. Andrea Martini, Sprecherin des Bündnisses Junge Ärztinnen und Ärzte (BJÄ) über den Frust des ärztlichen Nachwuchses und die Vorteile des Rucksack-Modells.

Bessere Prognose mit links- statt rechtsseitigem Kolon-Ca.

06.05.2024 Kolonkarzinom Nachrichten

Menschen mit linksseitigem Kolonkarzinom leben im Mittel zweieinhalb Jahre länger als solche mit rechtsseitigem Tumor. Auch aktuell ist das Sterberisiko bei linksseitigen Tumoren US-Daten zufolge etwa um 11% geringer als bei rechtsseitigen.

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.