Background
Methods
Patient selection
Data collection
Analysis of results
Results
Baseline characteristics
Number of cases | 148 |
---|---|
Gender Ratio (Male: Female) n | 90: 58 |
Median Age | 58 (47–71) |
Ethnicity (Asian: Black: White: Unknown) % | 31: 24: 36: 9 |
Median Diagnosis Serum creatinine μmol/L (IQR) (mg/dL) | 92 (68–183) (1.04, 0.77–2.07) |
Median Diagnosis Serum albumin g/L (IQR) (g/dL) | 25 (20–31) (2.5, 2–3.1) |
Median Diagnosis urine protein creatinine ratio mg/mmol (IQR) (mg/g) | 776 (432 – 1172) (7760, 4320–11,720) |
Median Diagnosis cholesterol mmol/L (IQR) (mg/dL) | 7.5 (5.75–9.25) (290, 222–357) |
Median Diagnosis bicarbonate mmol/L (IQR) | 25 (23–28) |
Mean Diagnosis haemoglobin g/L (SD) | 124.8 (21.68) |
Co-morbidities: Hypertension / Diabetes / Recurrent UTIs / Malignancy / Mental health issues n | 38 / 24 / 4 / 1 / 2 |
Complications: thrombotic event / treatment related side effect % | 13 / 5 |
Renin angiotensin system blockade medication use % | 84 |
Differences at diagnosis
Progression of biochemical parameters
Ethnicity differences
Ethnic group | N (%) |
---|---|
Asian | 45 (31) |
Black | 35 (24) |
White | 54 (36) |
Subgroups | |
African | 14 |
Caribbean | 21 |
Bangladeshi | 9 |
Chinese | 5 |
Indian | 17 |
Pakistani | 9 |
Middle Eastern | 5 |
Immunosuppression & Remission Status
Treatment | N (%) |
---|---|
Conservative | 48 (32) |
Cyclophosphamide | 36 (24) |
Calcineurin inhibitors | 38 (26) |
Antiproliferative agents (MMF/azathioprine) | 21 (14) |
Rituximab/steroid monotherapy/other | 1/3/1 (Total 3%) |