Skip to main content
Erschienen in: Archives of Osteoporosis 1/2018

01.12.2018 | Original Article

Morphometric semi-quantitative assessment of vertebral fractures in postmenopausal black women in Central Africa

verfasst von: Joseph Médard Kabeya Kabenkama, Lydie Banza, Jean Mukaya Tshibola, Jean–Marie Mbuyi Muamba, Rahma Rashid Tozin, Michel Lelo Tshikwela

Erschienen in: Archives of Osteoporosis | Ausgabe 1/2018

Einloggen, um Zugang zu erhalten

Abstract

Summary

This prospective and multi-centric study assessed the lacking of pattern in fractured patients and features of vertebral fractures in postmenopausal black women living in central Africa.

Introduction

Patients with osteoporosis commonly collapsed their vertebral body. This has been widely studied in Caucasians, Asians, and Americans and studies in black African are lacking. Our study was designed to establish a pattern of patients with fractures and determine the features of vertebral fractures in postmenopausal black women living in Central Africa.

Methods

A prospective and multi-centric study was conducted from June 2011 to June 2016, to assess the thoraco-lumbar-computed tomographic images of women. The menopausal statuses and anthropometric parameters (age, height, and weight) were collected. The body mass index and the Asset Poverty Index were evaluated. The reviews included a morphometric analysis of each vertebra that was rated according to the visual semi-quantitative system proposed by Genant et al.

Results

Four hundred thirty women aged 47–87 years old were included in this study. The mean age was 57 years old, and the mean menopause duration was 11.45 ± 6.6 years with extremes ranging from 2 to 37 years. The body mass indices were rated as overweight and obese in 80.8% of subjects and 54, 3% had high-API indices. Among the 4730 vertebrae analyzed, 529 (11.12%) were fractured, with 68.7% exhibited a cup-shaped deformation (biconcave), 19.8% had a wedge-shaped deformation, and 11.4% exhibited a cake (crush) deformation. Of the vertebras, 88.8% were grade 0, 5.5% grade 1, 5% grade 2, and 0.57% were grade 3. Of the women, 68.8% had one vertebra fractured and 31.2% had more than one fractured vertebrae.

Conclusion

This study seemed to determine the pattern and features of vertebral fractures in black African women which may be useful for comparisons with the pattern of worldwide populations.
Literatur
1.
Zurück zum Zitat Cooper C, Atkinson EJ, Kotowicz M, O’Fallon WM, Melton J III (1992) Secular trends in the incidence of postmenopausal vertebral fractures. Calcified tissue int 51:100–104CrossRef Cooper C, Atkinson EJ, Kotowicz M, O’Fallon WM, Melton J III (1992) Secular trends in the incidence of postmenopausal vertebral fractures. Calcified tissue int 51:100–104CrossRef
2.
Zurück zum Zitat Cipriani C, Pepe J, Bertoldo F, Bianchi G, Cantatore FP, Corrado A, di Stefano M, Frediani B, Gatti D, Giustina A, Porcelli T, Isaia G, Rossini M, Nieddu L, Minisola S, Girasole G, Pedrazzoni M (2017) The epidemiology of osteoporosis in Italian postmenopausal women according to the National Bone Health Alliance (NBHA) diagnostic criteria: a multicenter cohort study. J Endocrinol. https://doi.org/10.1007/s40618-017-0761-4 CrossRef Cipriani C, Pepe J, Bertoldo F, Bianchi G, Cantatore FP, Corrado A, di Stefano M, Frediani B, Gatti D, Giustina A, Porcelli T, Isaia G, Rossini M, Nieddu L, Minisola S, Girasole G, Pedrazzoni M (2017) The epidemiology of osteoporosis in Italian postmenopausal women according to the National Bone Health Alliance (NBHA) diagnostic criteria: a multicenter cohort study. J Endocrinol. https://​doi.​org/​10.​1007/​s40618-017-0761-4 CrossRef
3.
Zurück zum Zitat Felsenberg D, Silman AJ, Lunt M et al (2002) Incidence of vertebral fracture in Europe: results from the European Prospective Study (EPOS). J Bone Miner Res 114:716–724 Felsenberg D, Silman AJ, Lunt M et al (2002) Incidence of vertebral fracture in Europe: results from the European Prospective Study (EPOS). J Bone Miner Res 114:716–724
4.
Zurück zum Zitat Burge R, Dawson-Hughes B, Solomon DH, Wong JB, King A, Tosteson A (2007) Incidence and economic burden of osteoporosis-related fractures in the United States 2005-2025. J Bone Miner Res 22:465–475CrossRef Burge R, Dawson-Hughes B, Solomon DH, Wong JB, King A, Tosteson A (2007) Incidence and economic burden of osteoporosis-related fractures in the United States 2005-2025. J Bone Miner Res 22:465–475CrossRef
5.
Zurück zum Zitat Edmond SL, Kiel DP, Samelson EJ, Kelly-Hayes M, Felson DT (2005) Vertebral deformity, back symptoms, and functional limitations among older women: the Framingham study. Osteoporos Int 16:1086–1095CrossRef Edmond SL, Kiel DP, Samelson EJ, Kelly-Hayes M, Felson DT (2005) Vertebral deformity, back symptoms, and functional limitations among older women: the Framingham study. Osteoporos Int 16:1086–1095CrossRef
6.
Zurück zum Zitat Cauley JA, Hochberg MC, Lui LY, Palermo L, Ensrud KE, Hillier TA, Nevitt MC, Cummings SR (2007) Long-term risk of incident vertebral fractures. JAMA 298:2761–2767CrossRef Cauley JA, Hochberg MC, Lui LY, Palermo L, Ensrud KE, Hillier TA, Nevitt MC, Cummings SR (2007) Long-term risk of incident vertebral fractures. JAMA 298:2761–2767CrossRef
7.
Zurück zum Zitat Genant HK, Jergas M, Palermo L, Nevitt M, Valentin RS, Black D, Cummings SR (1996) Comparison of semiquantitative visual and quantitative morphometric assessment of prevalent and incident vertebral fractures in osteoporosis. The study of osteoporotic fractures research group. J Bone Miner Res 11(7):984–996CrossRef Genant HK, Jergas M, Palermo L, Nevitt M, Valentin RS, Black D, Cummings SR (1996) Comparison of semiquantitative visual and quantitative morphometric assessment of prevalent and incident vertebral fractures in osteoporosis. The study of osteoporotic fractures research group. J Bone Miner Res 11(7):984–996CrossRef
8.
Zurück zum Zitat Hospers IC, van der Laan JG, Zeebregts CJ, Nieboer P, Wolffenbuttel BHR, Dierckx RA, Kreeftenberg HG, Jager PL, Slart RHJA (2009) Vertebral fracture assessment in supine position: comparison by using conventional semiquantitative radiography and visual radiography. Radiology 251:822–828CrossRef Hospers IC, van der Laan JG, Zeebregts CJ, Nieboer P, Wolffenbuttel BHR, Dierckx RA, Kreeftenberg HG, Jager PL, Slart RHJA (2009) Vertebral fracture assessment in supine position: comparison by using conventional semiquantitative radiography and visual radiography. Radiology 251:822–828CrossRef
9.
Zurück zum Zitat Oei L, Rivadeneira F, Ly F et al (2013) Review of radiological scoring methods of osteoporotic vertebral fractures for clinical and research settings. Eur Radiol 23(2):476–414CrossRef Oei L, Rivadeneira F, Ly F et al (2013) Review of radiological scoring methods of osteoporotic vertebral fractures for clinical and research settings. Eur Radiol 23(2):476–414CrossRef
10.
Zurück zum Zitat Williams AL, Al-Busaidi A, Sparow PJ, Adams JE, Whitehouse RW (2009) Under-reporting of osteoporotic vertebral fractures on computed tomography. Eur J Radiol 17:179–183CrossRef Williams AL, Al-Busaidi A, Sparow PJ, Adams JE, Whitehouse RW (2009) Under-reporting of osteoporotic vertebral fractures on computed tomography. Eur J Radiol 17:179–183CrossRef
11.
Zurück zum Zitat Muller O (2008) Significance of sagittal reformations in routine spine CT studies for detecting osteoporotic fractures and other spine abnormalities. Eur Radiol 18:1696–1702CrossRef Muller O (2008) Significance of sagittal reformations in routine spine CT studies for detecting osteoporotic fractures and other spine abnormalities. Eur Radiol 18:1696–1702CrossRef
12.
Zurück zum Zitat Gausden EB, Nwachukwu BU, Schreiber JJ, Lorich DG, Lane JM (2017) Opportunistic use of CT imaging for osteoporosis screening and bone density assessment: a qualitative systematic review. J Bone Joint Surg Am 20 99(18):1580–1590CrossRef Gausden EB, Nwachukwu BU, Schreiber JJ, Lorich DG, Lane JM (2017) Opportunistic use of CT imaging for osteoporosis screening and bone density assessment: a qualitative systematic review. J Bone Joint Surg Am 20 99(18):1580–1590CrossRef
13.
Zurück zum Zitat Lee SJ, Anderson PA, Pickhardt PJ (2017) Predicting future hip fractures on routine abdominal CT using opportunistic osteoporosis screening measures: a matched case-control study. AJR Am J Roentgenol 209(2):395–340CrossRef Lee SJ, Anderson PA, Pickhardt PJ (2017) Predicting future hip fractures on routine abdominal CT using opportunistic osteoporosis screening measures: a matched case-control study. AJR Am J Roentgenol 209(2):395–340CrossRef
14.
Zurück zum Zitat Alacreu E, Moratal D, Arana E (2017) Opportunistic screening for osteoporosis by routine CT in southern Europe. Osteoporos Int 28(3):983–990CrossRef Alacreu E, Moratal D, Arana E (2017) Opportunistic screening for osteoporosis by routine CT in southern Europe. Osteoporos Int 28(3):983–990CrossRef
15.
Zurück zum Zitat Tracy JK, Meyer WA, Grigoryan M, Fan B, Flores RH, Genant HK, Resnik C, Hochberg MC (2006) Racial differences in the prevalence of vertebral fractures in older men: the Baltimore Men’s osteoporosis study. Osteoporos Int 17(1):99–104CrossRef Tracy JK, Meyer WA, Grigoryan M, Fan B, Flores RH, Genant HK, Resnik C, Hochberg MC (2006) Racial differences in the prevalence of vertebral fractures in older men: the Baltimore Men’s osteoporosis study. Osteoporos Int 17(1):99–104CrossRef
16.
Zurück zum Zitat WHO. Physical status: (1995) the use and interpretation of anthropometry. Report of a WHO Expert Committee. 1995 World Health Organ Tech Rep Ser.; 854:1–452 WHO. Physical status: (1995) the use and interpretation of anthropometry. Report of a WHO Expert Committee. 1995 World Health Organ Tech Rep Ser.; 854:1–452
17.
Zurück zum Zitat Frairbank JCT, Pynsent PB (2000) The Owestry disability index. Spine 25:2940–2953CrossRef Frairbank JCT, Pynsent PB (2000) The Owestry disability index. Spine 25:2940–2953CrossRef
18.
Zurück zum Zitat Fechtenbaum J, Cropet C, Kolta J et al (2005) The severity of vertebral fractures and health related quality of life in osteoporotic post-menopausal women. Osteoporosis int 16:2175–2179CrossRef Fechtenbaum J, Cropet C, Kolta J et al (2005) The severity of vertebral fractures and health related quality of life in osteoporotic post-menopausal women. Osteoporosis int 16:2175–2179CrossRef
19.
Zurück zum Zitat Conradie M, Conradie MM, Scher AT, Kidd M, Hough S (2015) Vertebral fracture prevalence in black and white South African women. Arch Osteoporos10:203 Conradie M, Conradie MM, Scher AT, Kidd M, Hough S (2015) Vertebral fracture prevalence in black and white South African women. Arch Osteoporos10:203
20.
Zurück zum Zitat Tozin R.R, Ngeleka M, Ingwen M et al (2000) Clinical feature of Congolense menopausal women. Annals of IRSS 1, 3: 19–22 Tozin R.R, Ngeleka M, Ingwen M et al (2000) Clinical feature of Congolense menopausal women. Annals of IRSS 1, 3: 19–22
21.
Zurück zum Zitat Van den Voort DJ, Geusens PP, Dinant GJ (2001) Risk factors for osteoporosis related to seer outcome fractures. Osteoporos Int 12:630–638CrossRef Van den Voort DJ, Geusens PP, Dinant GJ (2001) Risk factors for osteoporosis related to seer outcome fractures. Osteoporos Int 12:630–638CrossRef
22.
Zurück zum Zitat Laet D, Kanis JA, Oden A et al (2005) Bodymass index as a predictor of fracture risk; a meta-analysis. Osteoporos Int 6:1330–1338CrossRef Laet D, Kanis JA, Oden A et al (2005) Bodymass index as a predictor of fracture risk; a meta-analysis. Osteoporos Int 6:1330–1338CrossRef
23.
Zurück zum Zitat Leslie WD, Morin SN, Majumdar SR, Lix LM (2017) Effects of obesity and diabetes on rate of bone density loss. Osteoporos Int 9:4223–4229 Leslie WD, Morin SN, Majumdar SR, Lix LM (2017) Effects of obesity and diabetes on rate of bone density loss. Osteoporos Int 9:4223–4229
24.
Zurück zum Zitat Lau E, Ong K, Kurtz S, Schmier J, Edidin A (2008) Mortality following the diagnosis of a vertebral compression fracture in the Medicare population. J Bone Joint Surg Am 90:1479–1486CrossRef Lau E, Ong K, Kurtz S, Schmier J, Edidin A (2008) Mortality following the diagnosis of a vertebral compression fracture in the Medicare population. J Bone Joint Surg Am 90:1479–1486CrossRef
25.
Zurück zum Zitat Ganesan S, Acharya AS, Chauhan R, Acharya S (2017) Prevalence and risk factors for low back pain in 1,355 young adults: a cross-sectional study. Asian Spine J 11(4):610–617CrossRef Ganesan S, Acharya AS, Chauhan R, Acharya S (2017) Prevalence and risk factors for low back pain in 1,355 young adults: a cross-sectional study. Asian Spine J 11(4):610–617CrossRef
26.
Zurück zum Zitat Bauer JS, Muller D, Ambekar A et al (2006) Detection of osteoporotic vertebral fractures using multidetector CT. Osteoporos Int 17:608–615CrossRef Bauer JS, Muller D, Ambekar A et al (2006) Detection of osteoporotic vertebral fractures using multidetector CT. Osteoporos Int 17:608–615CrossRef
27.
Zurück zum Zitat Adebajo AO (1991) Fractures of the hip and distal forearm in west Africa and the United Kingdom. Ageing 20:435–438 Adebajo AO (1991) Fractures of the hip and distal forearm in west Africa and the United Kingdom. Ageing 20:435–438
28.
Zurück zum Zitat Muller D, Bauer JS, Zeile M, Rummeny EJ, Link TM (2008) Significance of sagittal reformations in routine thoracic and abdominal multislice CT studies for detecting osteoporotic fractures and other spine abnormalities. Eur Radiol 18:1696–1702CrossRef Muller D, Bauer JS, Zeile M, Rummeny EJ, Link TM (2008) Significance of sagittal reformations in routine thoracic and abdominal multislice CT studies for detecting osteoporotic fractures and other spine abnormalities. Eur Radiol 18:1696–1702CrossRef
29.
Zurück zum Zitat Mukaya J, Kabeya JM, Kolela G, Tshienda S, Mbuyi-Muamba JM (2012) Radiological and clinical profile of spinal disease in Congolese: a report of 1209 observations at St Joseph hospital. Ann Afr Med 6(1):1260–1278 Mukaya J, Kabeya JM, Kolela G, Tshienda S, Mbuyi-Muamba JM (2012) Radiological and clinical profile of spinal disease in Congolese: a report of 1209 observations at St Joseph hospital. Ann Afr Med 6(1):1260–1278
30.
Zurück zum Zitat Mark Lunt, Terence W, O’Neill et al (2003) Characteristics of a prevalent vertebral deforming predict subsequent vertebral fracture: results from the European prospective osteoporosis study (EPOS). Bone 33: 505–513CrossRef Mark Lunt, Terence W, O’Neill et al (2003) Characteristics of a prevalent vertebral deforming predict subsequent vertebral fracture: results from the European prospective osteoporosis study (EPOS). Bone 33: 505–513CrossRef
31.
Zurück zum Zitat Luckey MM, Wallestrein S, Lapinksi R et al (1996) A prospective study, of bone loss in African-American and white women: a clinical research center study. J Clin Endocrinol Metab 81:2948–2954PubMed Luckey MM, Wallestrein S, Lapinksi R et al (1996) A prospective study, of bone loss in African-American and white women: a clinical research center study. J Clin Endocrinol Metab 81:2948–2954PubMed
32.
Zurück zum Zitat Aspray TJ (1995) Low bone mineral content is common but osteoporotic fractures are rare in elderly Gambian women. J Bone Miner Res 10:890–902 Aspray TJ (1995) Low bone mineral content is common but osteoporotic fractures are rare in elderly Gambian women. J Bone Miner Res 10:890–902
33.
Zurück zum Zitat Em L (1996) Normal ranges for vertebral height ratio and prevalence of vertebral fracture in Hong Kong Chinese: a comparrison with american caucasians. J Bone Miner Res 11(9):1364–1368 Em L (1996) Normal ranges for vertebral height ratio and prevalence of vertebral fracture in Hong Kong Chinese: a comparrison with american caucasians. J Bone Miner Res 11(9):1364–1368
34.
Zurück zum Zitat Freedman BA, Potter BK, Nesti LJ, Giuliani JR, Hampton C, Kuklo TR (2008) Osteoporosis and vertebral compression fractures continued missed opportunities. Spine J 8:756–762CrossRef Freedman BA, Potter BK, Nesti LJ, Giuliani JR, Hampton C, Kuklo TR (2008) Osteoporosis and vertebral compression fractures continued missed opportunities. Spine J 8:756–762CrossRef
35.
Zurück zum Zitat O’Neill TW, Felsenberg D, Varlow J, Cooper C, Kanis JA, Silman AJ (1996) The prevalence of vertebral deformity in European men and women, the European vertebral osteoporosis study. JBone Miner Res 11:1010–1018CrossRef O’Neill TW, Felsenberg D, Varlow J, Cooper C, Kanis JA, Silman AJ (1996) The prevalence of vertebral deformity in European men and women, the European vertebral osteoporosis study. JBone Miner Res 11:1010–1018CrossRef
36.
Zurück zum Zitat Delmas PD, Van de Langerijt L, Watts NB et al (2005) Underdiagnosis of vertebral fractures is a worldwide problem: the IMPACT study. Bone Miner Res 20(4):557–563CrossRef Delmas PD, Van de Langerijt L, Watts NB et al (2005) Underdiagnosis of vertebral fractures is a worldwide problem: the IMPACT study. Bone Miner Res 20(4):557–563CrossRef
37.
Zurück zum Zitat Grados F, Fechtenbaum J, Flipon E, Kolta S, Roux C, Fardellone P (2009) Radiographic methods for evaluating osteoporotic vertebral fractures). Rhumatisme 76:397–404CrossRef Grados F, Fechtenbaum J, Flipon E, Kolta S, Roux C, Fardellone P (2009) Radiographic methods for evaluating osteoporotic vertebral fractures). Rhumatisme 76:397–404CrossRef
39.
Zurück zum Zitat Black DM, Palermo L, Nevitt MC, Genant HK, Epstein R, San Valentin R, Cummings SR (1995) Comparison of methods for defining prevalent vertebral deformities: the study of osteoporotic fractures. J Bone Miner Res 10:890–902CrossRef Black DM, Palermo L, Nevitt MC, Genant HK, Epstein R, San Valentin R, Cummings SR (1995) Comparison of methods for defining prevalent vertebral deformities: the study of osteoporotic fractures. J Bone Miner Res 10:890–902CrossRef
40.
Zurück zum Zitat Grados F, Fechtenbaum J, Flipon E, Kolta S, Roux C, Fardellone P (2009) Radiographic methods for evaluating osteoporotic vertebral fractures. Rhumatisme 76(2009):397–404CrossRef Grados F, Fechtenbaum J, Flipon E, Kolta S, Roux C, Fardellone P (2009) Radiographic methods for evaluating osteoporotic vertebral fractures. Rhumatisme 76(2009):397–404CrossRef
Metadaten
Titel
Morphometric semi-quantitative assessment of vertebral fractures in postmenopausal black women in Central Africa
verfasst von
Joseph Médard Kabeya Kabenkama
Lydie Banza
Jean Mukaya Tshibola
Jean–Marie Mbuyi Muamba
Rahma Rashid Tozin
Michel Lelo Tshikwela
Publikationsdatum
01.12.2018
Verlag
Springer London
Erschienen in
Archives of Osteoporosis / Ausgabe 1/2018
Print ISSN: 1862-3522
Elektronische ISSN: 1862-3514
DOI
https://doi.org/10.1007/s11657-018-0431-y

Weitere Artikel der Ausgabe 1/2018

Archives of Osteoporosis 1/2018 Zur Ausgabe

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

26.04.2024 Hüft-TEP Nachrichten

Ob bei einer Notfalloperation nach Schenkelhalsfraktur eine Hemiarthroplastik oder eine totale Endoprothese (TEP) eingebaut wird, sollte nicht allein vom Alter der Patientinnen und Patienten abhängen. Auch über 90-Jährige können von der TEP profitieren.

Arthroskopie kann Knieprothese nicht hinauszögern

25.04.2024 Gonarthrose Nachrichten

Ein arthroskopischer Eingriff bei Kniearthrose macht im Hinblick darauf, ob und wann ein Gelenkersatz fällig wird, offenbar keinen Unterschied.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Ärztliche Empathie hilft gegen Rückenschmerzen

23.04.2024 Leitsymptom Rückenschmerzen Nachrichten

Personen mit chronischen Rückenschmerzen, die von einfühlsamen Ärzten und Ärztinnen betreut werden, berichten über weniger Beschwerden und eine bessere Lebensqualität.

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.