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Current Neurology and Neuroscience Reports
Erschienen in: Current Neurology and Neuroscience Reports 6/2018

01.06.2018 | Epilepsy (CW Bazil, Section Editor)

Neurostimulation for Memory Enhancement in Epilepsy

verfasst von: Stephen Meisenhelter, Barbara C. Jobst

Erschienen in: Current Neurology and Neuroscience Reports | Ausgabe 6/2018

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Abstract

Purpose of Review

Memory is one of the top concerns of epilepsy patients, but there are no known treatments to directly alleviate the memory deficits associated with epilepsy. Neurostimulation may provide new therapeutic tools to enhance memory in epilepsy patients. Here, we critically review recent investigations of memory enhancement using transcranial electrical stimulation (tES), transcranial magnetic stimulation (TMS), vagus nerve stimulation (VNS), chronic intracranial stimulation, and acute intracranial stimulation.

Recent Findings

Existing literature suggests that transcranial direct current stimulation (tDCS) produces a small enhancement in memory in neuropsychological patients, but transcranial alternating current stimulation (tACS) and transcranial random noise stimulation (tRNS) have not been found to have an effect on memory. Most studies of transcranial magnetic stimulation (TMS) have found that TMS has no positive effect on memory. Vagus nerve stimulation can acutely enhance memory, while chronic therapy does not appear to alter memory performance. We found that there is the most evidence for significant memory enhancement using intracranial stimulation techniques, especially chronic stimulation of the fornix and task-responsive stimulation of the lateral temporal lobe.

Summary

Presently, there are no existing therapeutic options for directly treating epilepy-related memory deficits. While neurostimulation technologies for memory enhancement are largely still in the experimental phase, neurostimulation appears promising as a future technique for treating epilepsy-related memory deficits.
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Metadaten
Titel
Neurostimulation for Memory Enhancement in Epilepsy
verfasst von
Stephen Meisenhelter
Barbara C. Jobst
Publikationsdatum
01.06.2018
Verlag
Springer US
Erschienen in
Current Neurology and Neuroscience Reports / Ausgabe 6/2018
Print ISSN: 1528-4042
Elektronische ISSN: 1534-6293
DOI
https://doi.org/10.1007/s11910-018-0837-3

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