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Lasers in Medical Science

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26.08.2021 | Original Article

New evidence from hyperspectral imaging analysis on the effect of photobiomodulation therapy on normal skin oxygenation

verfasst von: Mihaela Antonina Calin, Adrian Macovei, Roxana Savastru, Adriana Sarah Nica, Sorin Viorel Parasca

Erschienen in: Lasers in Medical Science | Ausgabe 3/2022

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Abstract

The aim of this study was to assess the changes induced by photobiomodulation therapy in oxygenation of normal skin and underlying tissue using hyperspectral imaging combined with a chemometric regression approach. Eleven healthy adult volunteers were enrolled in this study. The dorsal side of the left hand of each subject was exposed to photobiomodulation therapy, while the correspondent side of the right hand was used as a control (placebo effect). Laser irradiation was performed with a laser diode system (635 nm, 15mW, 9 J/cm²) for 900 s. Changes in skin oxygenation were assessed before and after applying the photobiomodulation therapy and placebo using the hyperspectral imaging. Hyperspectral data analysis showed that variations of oxyhemoglobin and deoxyhemoglobin concentrations had no statistical significance in both groups. In conclusion, photobiomodulation therapy does not induce changes in oxyhemoglobin and deoxyhemoglobin concentrations in the normal skin measured from hyperspectral images, at least at λ = 635 nm and 900-s exposure time.

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Titel: New evidence from hyperspectral imaging analysis on the effect of photobiomodulation therapy on normal skin oxygenation
verfasst von: Mihaela Antonina Calin
Adrian Macovei
Roxana Savastru
Adriana Sarah Nica
Sorin Viorel Parasca
Publikationsdatum: 26.08.2021
Verlag: Springer London
Erschienen in: Lasers in Medical Science / Ausgabe 3/2022
Print ISSN: 0268-8921
Elektronische ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-021-03397-9

Live-Webinar "Chronische Unterbauch- und Viszeralschmerzen in der Praxis managen"

Springer Medizin

New evidence from hyperspectral imaging analysis on the effect of photobiomodulation therapy on normal skin oxygenation

Abstract

Live-Webinar "Chronische Unterbauch- und Viszeralschmerzen in der Praxis managen"

Springer Medizin

Abstract

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