Erschienen in:
11.10.2016 | Case report
Novel combination chemotherapy with radiotherapy for prostate squamous cell carcinoma
verfasst von:
Mitsutaka Onoda, Ryo Sugimoto, Noriyuki Uesugi, Misato Takayama, Ei Shiomi, Renpei Kato, Yoichiro Kato, Ryo Takata, So Omori, Wataru Obara
Erschienen in:
International Cancer Conference Journal
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Ausgabe 1/2017
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Abstract
Squamous cell carcinoma of the prostate is a rare tumor. It has been typically described as an aggressive cancer, with a median survival time of 14 months. We present a case of locally advanced squamous cell carcinoma of the prostate with a regional lymph node metastasis. The patient received a novel combination chemotherapy regimen, docetaxel, cisplatin, and 5-fluorouracil, with radiotherapy to the whole pelvis and prostate. He was subsequently treated with seven courses of docetaxel, cisplatin, and 5-fluorouracil chemotherapy without any severe adverse events. We identified a 60.1 % reduction in the prostatic tumor, and the lymph node metastasis was shrunk after chemotherapy. A needle biopsy of the prostate after chemotherapy revealed no malignancy. No recurrence has been observed for 24 months. A combination of docetaxel, cisplatin, and 5-fluorouracil chemotherapy and radiotherapy might be an effective therapy for squamous cell carcinoma of the prostate.