Erschienen in:
01.01.2013 | Letter to the Editor
O blood group and the risk of major bleeding: a single-center survey
verfasst von:
Massimo Franchini, Silvia Crestani, Chiara Rossi, Francesco Frattini, Carlo Mengoli, Ivano Giacomini, Mario Luppi, Carlo Bonfanti
Erschienen in:
Journal of Thrombosis and Thrombolysis
|
Ausgabe 1/2013
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Excerpt
Since the first description in the 1960 [
1], a number of studies have documented that ABO blood group has a profound influence on hemostasis, as it is a major determinant of plasma levels of von Willebrand factor (VWF) and consequently, since VWF acts as a specific carrier of factor VIII (FVIII) and protects it from proteolytic degradation, of FVIII [
2‐
5]. …