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01.06.2017 | AdisInsight Report

Ocrelizumab: First Global Approval

verfasst von: James E. Frampton

Erschienen in: Drugs | Ausgabe 9/2017

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Abstract

Ocrelizumab (Ocrevus™) is a humanised anti-CD20 monoclonal antibody that has been developed by Genentech, Inc. (a subsidiary of Roche) for the treatment of multiple sclerosis (MS). The drug is designed to deplete B cells, which play an important role in the pathogenesis of MS. In March 2017, ocrelizumab was approved in the USA for the treatment of patients with relapsing or primary progressive forms of MS; currently, it is awaiting approval in the EU for the same indications. This article summarizes the milestones in the development of ocrelizumab leading to its first global approval for the treatment of MS.

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Titel: Ocrelizumab: First Global Approval
verfasst von: James E. Frampton
Publikationsdatum: 01.06.2017
Verlag: Springer International Publishing
Erschienen in: Drugs / Ausgabe 9/2017
Print ISSN: 0012-6667
Elektronische ISSN: 1179-1950
DOI: https://doi.org/10.1007/s40265-017-0757-6

Springer Medizin

Abstract

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