Background
Methods
Patient selection
Definition of structural heart disease
Irrigated radiofrequency ablation
Procedure success and follow-up
Statistics
Results
Patient characteristics
Total (n = 266) | SHD (n = 109) | No SHD (n = 157) | p value (SHD vs. no SHD) | |
---|---|---|---|---|
Male gender | 157 (59) | 88 (80.7) | 69 (44.0) | < 0.001* |
Age, years | 53.7 ± 16.4 | 59.1 ± 14.7 | 49.9 ± 16.5 | < 0.001* |
Body mass index, kg/m2 | 26.6 ± 4.8 | 27.1 ± 4.3 | 26.3 ± 5.1 | 0.139 |
LVEF, % | 56 ± 10 | 49 ± 11 | 60 ± 6 | < 0.001* |
ICD | 30 (11.3) | 28 (25.7) | 2 (1.3) | < 0.001* |
Hypertension | 122 (45.9) | 68 (62.4) | 54 (34.4) | < 0.001* |
Diabetes | 19 (7.1) | 13 (11.9) | 6 (3.8) | 0.015* |
Arrhythmias | ||||
VT | 31 (11.7) | 21 (19.3) | 10 (6.4) | 0.002* |
VT + PVC | 42 (15.8) | 20 (18.3) | 22 (14.0) | 0.396 |
PVC | 193 (72.6) | 68 (62.4) | 125 (79.6) | 0.003* |
Acute success | 246 (92.5) | 98 (89.9) | 148 (94.3) | 0.238 |
Procedural success
Total (n = 266) | SHD (n = 109) | No SHD (n = 157) | p value (SHD vs. no SHD) | |
---|---|---|---|---|
RV origin | 121 (45.5) | 37 (33.9) | 84 (53.5) | 0.002* |
RVOT | 108 (40.6) | 30 (27.5) | 78 (49.7) | < 0.001* |
RV (other) | 13 (4.9) | 7 (6.4) | 6 (3.8) | 0.392 |
LV origin | 145 (54.5) | 72 (66.0) | 73 (46.5) | 0.002* |
LVOT | 16 (6.0) | 5 (4.6) | 11 (7.0) | 0.601 |
LCC/RCC/NCC | 47 (17.7) | 22 (20.2) | 25 (15.9) | 0.415 |
AMC | 16 (6.0) | 3 (2.8) | 13 (8.3) | 0.071 |
GCV | 12 (4.5) | 6 (5.5) | 6 (3.8) | 0.577 |
MVA | 4 (1.5) | 3 (2.8) | 1 (0.6) | 0.308 |
Papillary muscles | 2 (0.8) | 2 (1.8) | 0 | 0.167 |
LV summit | 2 (0.8) | 1 (0.9) | 1 (0.6) | > 0.999 |
LV septal | 13 (4.9) | 11 (10.1) | 2 (1.3) | 0.002* |
LV inf./posterior | 18 (6.8) | 11 (10.1) | 7 (4.5) | 0.085 |
LV anterior | 5 (1.9) | 3 (2.8) | 2 (1.3) | 0.403 |
LV lateral | 1(0.4) | 1 (0.9) | 0 | 0.410 |
LV (other) | 9 (3.4) | 4 (3.7) | 5 (3.2) | > 0.999 |
Total (n = 266) | SHD (n = 109) | No SHD (n = 157) | p value (SHD vs. no SHD) | |
---|---|---|---|---|
Total complications | 15 (5.6) | 6 (5.5) | 9 (5.7) | > 0.999 |
Major complications | 4 (1.5) | 1 (0.9) | 3 (1.9) | 0.648 |
Complication type | ||||
Arteriovenous fistula | 4 (1.5) | 3 (2.8) | 1 (0.6) | |
Groin hematoma | 2 (0.8) | 0 | 2 (1.2) | |
Pseudoaneurysm | 4 (1.5) | 2 (1.8) | 2 (1.2) | |
Pericardial effusion | 2 (0.8) | 0 | 2 (1.2) | |
Other | 3 (1.1) | 1 (0.9) | 2 (1.2) |
Follow-up
Total (n = 256) | SHD (n = 102) | No SHD (n = 154) | p value (SHD vs. no SHD) | |
---|---|---|---|---|
Duration of follow-up, months | 34.7 ± 15.1 | 36.6 ± 15.2 | 33.4 ± 15.0 | 0.101 |
Patients with repeat ablation of any VA, n (%) | 47 (18.4) | 23 (22.5) | 24 (15.6) | 0.189 |
Patients with repeat ablation of initial VA, n (%) | 40 (15.6) | 20 (19.6) | 20 (13.0) | 0.179 |
PVC burden at baseline, % | 17.0 ± 13.4 | 16.9 ± 13.8 | 17.1 ± 13.2 | 0.901 |
PVC burden at follow-up, % | 3.8 ± 7.8 | 5.5 ± 9.5 | 2.8 ± 6.4 | 0.005* |
PVC count at baseline, n | 17,324 ± 14,918 | 16,208 ± 14,568 | 17,979 ± 15,147 | 0.309 |
PVC count at follow-up, n | 3620 ± 7327 | 5154 ± 8617 | 2720 ± 6322 | 0.002* |
LVEF at baseline, % | 56 ± 10 | 49 ± 11 | 60 ± 6 | < 0.001* |
LVEF at follow-up, % | 56 ± 10 | 50 ± 12 | 60 ± 5 | < 0.001* |
AAD at baseline, n (%) | 150 (59.0) | 80 (78.4) | 70 (45.5) | < 0.001* |
AAD at follow-up, n (%) | 142 (55.5) | 82 (80.4) | 60 (39.0) | < 0.001* |
Time to repeat ablation, months | 11.5 ± 11.3 | 11.3 ± 9.8 | 11.8 ± 12.4 | 0.892 |
Subgroup (total n = 256) | Patients with repeat ablation (n = 40) | p value (SHD subgroup vs. no SHD) |
---|---|---|
Patients with ICM (n = 42) | 6 (14.3) | 0.801 |
Patients with DCM (n = 25) | 8 (32.0) | 0.022* |
Patients with HCM (n = 11) | 2 (18.2) | 0.643 |
Patients with myocarditis (n = 12) | 3 (25) | 0.220 |
Patients with other SHD (n = 12) | 1 (8.3) | > 0.999 |
Patients without SHD (n = 154) | 20 (13.0) |