Background
Patients and Methods
Inclusion Criteria
Patients
Experimental group (cases) | Control group (cases) | ||
---|---|---|---|
Tumor location | upper arm | 3 | 3 |
Thigh | 7 | 11 | |
lower leg | 5 | 2 | |
Pathological phenotypes | malignant fibrous histiocytoma | 8 | 6 |
rhabdomyosarcoma | 3 | 3 | |
synovial sarcoma | 0 | 4 | |
malignant nerve sheath tumor | 1 | 1 | |
clear cell sarcoma | 2 | 0 | |
unclassifiable | 1 | 2 | |
Cytological grading | G2 | 0 | 1 |
G3 | 15 | 15 |
Treatment Regimen
Endpoints and adverse reactions
Statistical Analyses
Results
Experimental group (cases) | Control group (cases) | p value | ||
---|---|---|---|---|
Chemotherapy response | CR | 2 | 1 | <0.05 |
PR | 11 | 5 | ||
SD | 2 | 10 | ||
Surgical margin | Negative | 13 | 6 | <0.01 |
Positive | 2 | 10 | ||
Progression free survival | Yes | 10 | 4 | <0.05 |
No | 5 | 12 |
AE | Grade (CTCAEv3.0) | Experimental group (cases) | Control group (cases) | p value |
---|---|---|---|---|
Nausea | 1 (mild) | 9 | 10 | >0.05 |
2 (moderate) | 4 | 5 | ||
Vomiting | 1 (mild) | 5 | 7 | >0.05 |
2 (moderate) | 1 | 1 | ||
Asthenia | 1 (mild) | 6 | 4 | >0.05 |
2 (moderate) | 0 | 0 | ||
Granulocytopenia | 1 (mild) | 7 | 8 | >0.05 |
2 (moderate) | 2 | 0 | ||
Anaemia | 1 (mild) | 2 | 1 | >0.05 |
2 (moderate) | 0 | 0 | ||
Peripheral Neuropathy | 1 (mild) | 12 | 0 | Not Comparable |
2 (moderate) | 3 | 0 |
Chemotherapy response | Surgical margin | Tumor-free survival | ||
---|---|---|---|---|
Chemotherapy Regimen | Pearson correlation | 0.484 | 0.504 | 0.418 |
Sig. (2-tailed) | <0.01 | <0.01 | <0.05 | |
Chemotherapy response | Pearson correlation | 0.965 | 0.683 | |
Sig. (2-tailed) | <0.001 | <0.001 | ||
Surgical margin | Pearson correlation | 0.721 | ||
Sig. (2-tailed) | <0.001 |