Skip to main content
Erschienen in: Clinical Orthopaedics and Related Research® 5/2014

01.05.2014 | Symposium: Perioperative Pain Management in Orthopaedic Surgery

Peripheral Nerve Blocks in Shoulder Arthroplasty: How Do They Influence Complications and Length of Stay?

verfasst von: Ottokar Stundner, MD, Rehana Rasul, MA, MPH, Ya-Lin Chiu, MS, Xuming Sun, MS, Madhu Mazumdar, MA, MS, PhD, Chad M. Brummett, MD, Reinhold Ortmaier, MD, Stavros G. Memtsoudis, MD, PhD, FCCP

Erschienen in: Clinical Orthopaedics and Related Research® | Ausgabe 5/2014

Einloggen, um Zugang zu erhalten

Abstract

Background

Regional anesthesia has proven to be a highly effective technique for pain control after total shoulder arthroplasty. However, concerns have been raised about the safety of upper-extremity nerve blocks, particularly with respect to the incidence of perioperative respiratory and neurologic complications, and little is known about their influence, if any, on length of stay after surgery.

Questions/purposes

Using a large national cohort, we asked: (1) How frequently are upper-extremity peripheral nerve blocks added to general anesthesia in patients undergoing total shoulder arthroplasty? (2) Are there differences in the incidence of and adjusted risk for major perioperative complications and mortality between patients receiving general anesthesia with and without nerve blocks? And (3) does resource utilization (blood product transfusion, intensive care unit admission, length of stay) differ between groups?

Methods

We searched a nationwide discharge database for patients undergoing total shoulder arthroplasty under general anesthesia with or without addition of a nerve block. Groups were compared with regard to demographics, comorbidities, major perioperative complications, and length of stay. Multivariable logistic regressions were performed to measure complications and resource use. A negative binomial regression was fitted to measure length of stay.

Results

We identified 17,157 patients who underwent total shoulder arthroplasty between 2007 and 2011. Of those, approximately 21% received an upper-extremity peripheral nerve block in addition to general anesthesia. Patients receiving combined regional-general anesthesia had similar mean age (68.6 years [95% CI: 68.2–68.9 years] versus 69.1 years [95% CI: 68.9–69.3 years], p < 0.0043), a slightly lower mean Deyo (comorbidity) index (0.87 versus 0.93, p = 0.0052), and similar prevalence of individual comorbidities, compared to those patients receiving general anesthesia only. Addition of regional anesthesia was not associated with different odds ratios for complications, transfusion, and intensive care unit admission. Incident rates for length of stay were also similar between groups (incident rate ratio = 0.99; 95% CI: 0.97–1.02; p = 0.467)

Conclusions

Addition of regional to general anesthesia was not associated with an increased complication profile or increased use of resources. In combination with improved pain control as known from previous research, regional anesthesia may represent a viable management option for shoulder arthroplasty. However, further research is necessary to better clarify the risk of neurologic complications.

Level of Evidence

Level IV, therapeutic study. See Instructions for Authors for a complete description of levels of evidence.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Aguirre J, Del Moral A, Cobo I, Borgeat A, Blumenthal S. The role of continuous peripheral nerve blocks. Anesthesiol Res Pract. 2012;2012:560879.PubMedCentralPubMed Aguirre J, Del Moral A, Cobo I, Borgeat A, Blumenthal S. The role of continuous peripheral nerve blocks. Anesthesiol Res Pract. 2012;2012:560879.PubMedCentralPubMed
2.
Zurück zum Zitat Austin P, Rothwell DM, Tu JV. A comparison of statistical modeling strategies for analyzing length of stay after CABG surgery. Health Services & Outcomes Research Methodology. 2002;3:107–133.CrossRef Austin P, Rothwell DM, Tu JV. A comparison of statistical modeling strategies for analyzing length of stay after CABG surgery. Health Services & Outcomes Research Methodology. 2002;3:107–133.CrossRef
3.
Zurück zum Zitat Bhatia A, Lai J, Chan VW, Brull R. Case report: pneumothorax as a complication of the ultrasound-guided supraclavicular approach for brachial plexus block. Anesth Analg. 2010;111:817–819.PubMedCrossRef Bhatia A, Lai J, Chan VW, Brull R. Case report: pneumothorax as a complication of the ultrasound-guided supraclavicular approach for brachial plexus block. Anesth Analg. 2010;111:817–819.PubMedCrossRef
4.
Zurück zum Zitat Borgeat A, Ekatodramis G, Kalberer F, Benz C. Acute and nonacute complications associated with interscalene block and shoulder surgery: a prospective study. Anesthesiology. 2001;95:875–880.PubMedCrossRef Borgeat A, Ekatodramis G, Kalberer F, Benz C. Acute and nonacute complications associated with interscalene block and shoulder surgery: a prospective study. Anesthesiology. 2001;95:875–880.PubMedCrossRef
5.
Zurück zum Zitat Brandl F, Taeger K. [The combination of general anesthesia and interscalene block in shoulder surgery] [in German]. Anaesthesist. 1991;40:537–542.PubMed Brandl F, Taeger K. [The combination of general anesthesia and interscalene block in shoulder surgery] [in German]. Anaesthesist. 1991;40:537–542.PubMed
6.
Zurück zum Zitat Claeys MJ, Sinnaeve PR, Convens C, Dubois P, Boland J, Vranckx P, Gevaert S, Coussement P, Beauloye C, Renard M, Vrints C, Evrard P. Inter-hospital variation in length of hospital stay after ST-elevation myocardial infarction: results from the Belgian STEMI registry. Acta Cardiol. 2013;68:235–239.PubMed Claeys MJ, Sinnaeve PR, Convens C, Dubois P, Boland J, Vranckx P, Gevaert S, Coussement P, Beauloye C, Renard M, Vrints C, Evrard P. Inter-hospital variation in length of hospital stay after ST-elevation myocardial infarction: results from the Belgian STEMI registry. Acta Cardiol. 2013;68:235–239.PubMed
7.
Zurück zum Zitat Deyo RA, Cherkin DC, Ciol MA. Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. J Clin Epidemiol. 1992;45:613–619.PubMedCrossRef Deyo RA, Cherkin DC, Ciol MA. Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. J Clin Epidemiol. 1992;45:613–619.PubMedCrossRef
8.
Zurück zum Zitat Gaughan J, Kobel C, Linhart C, Mason A, Street A, Ward P. Why do patients having coronary artery bypass grafts have different costs or length of stay? An analysis across 10 European countries. Health Econ. 2012;21(suppl 2):77–88.PubMedCrossRef Gaughan J, Kobel C, Linhart C, Mason A, Street A, Ward P. Why do patients having coronary artery bypass grafts have different costs or length of stay? An analysis across 10 European countries. Health Econ. 2012;21(suppl 2):77–88.PubMedCrossRef
9.
Zurück zum Zitat Guay J. The effect of neuraxial blocks on surgical blood loss and blood transfusion requirements: a meta-analysis. J Clin Anesth. 2006;18:124–128.PubMedCrossRef Guay J. The effect of neuraxial blocks on surgical blood loss and blood transfusion requirements: a meta-analysis. J Clin Anesth. 2006;18:124–128.PubMedCrossRef
10.
Zurück zum Zitat Hortense A, Perez MV, Amaral JL, Oshiro AC, Rossetti HB. Interscalene brachial plexus block: effects on pulmonary function. Rev Bras Anestesiol. 2010;60:130–137, 74–78. Hortense A, Perez MV, Amaral JL, Oshiro AC, Rossetti HB. Interscalene brachial plexus block: effects on pulmonary function. Rev Bras Anestesiol. 2010;60:130–137, 74–78.
11.
Zurück zum Zitat Hosmer DW, Lemeshow S. Applied Logistic Regression. New York, NY: John Wiley & Sons Inc; 2000:162.CrossRef Hosmer DW, Lemeshow S. Applied Logistic Regression. New York, NY: John Wiley & Sons Inc; 2000:162.CrossRef
12.
Zurück zum Zitat Hosmer DW, Lemeshow SA. Goodness-of-fit test for the multiple logistic regression model. Commun Stat. 1980;A10:1043–1069.CrossRef Hosmer DW, Lemeshow SA. Goodness-of-fit test for the multiple logistic regression model. Commun Stat. 1980;A10:1043–1069.CrossRef
13.
Zurück zum Zitat llfeld BM. Continuous peripheral nerve blocks: a review of the published evidence. Anesth Analg. 2011;113:904–925. llfeld BM. Continuous peripheral nerve blocks: a review of the published evidence. Anesth Analg. 2011;113:904–925.
14.
Zurück zum Zitat Ilfeld BM, Vandenborne K, Duncan PW, Sessler DI, Enneking FK, Shuster JJ, Theriaque DW, Chmielewski TL, Spadoni EH, Wright TW. Ambulatory continuous interscalene nerve blocks decrease the time to discharge readiness after total shoulder arthroplasty: a randomized, triple-masked, placebo-controlled study. Anesthesiology. 2006;105:999–1007.PubMedCrossRef Ilfeld BM, Vandenborne K, Duncan PW, Sessler DI, Enneking FK, Shuster JJ, Theriaque DW, Chmielewski TL, Spadoni EH, Wright TW. Ambulatory continuous interscalene nerve blocks decrease the time to discharge readiness after total shoulder arthroplasty: a randomized, triple-masked, placebo-controlled study. Anesthesiology. 2006;105:999–1007.PubMedCrossRef
15.
Zurück zum Zitat Ilfeld BM, Wright TW, Enneking FK, Morey TE. Joint range of motion after total shoulder arthroplasty with and without a continuous interscalene nerve block: a retrospective, case-control study. Reg Anesth Pain Med. 2005;30:429–433.PubMed Ilfeld BM, Wright TW, Enneking FK, Morey TE. Joint range of motion after total shoulder arthroplasty with and without a continuous interscalene nerve block: a retrospective, case-control study. Reg Anesth Pain Med. 2005;30:429–433.PubMed
16.
Zurück zum Zitat Kessler ER, Shah M, Gruschkus SK, Raju A. Cost and quality implications of opioid-based postsurgical pain control using administrative claims data from a large health system: opioid-related adverse events and their impact on clinical and economic outcomes. Pharmacotherapy. 2013;33:383–391.PubMedCrossRef Kessler ER, Shah M, Gruschkus SK, Raju A. Cost and quality implications of opioid-based postsurgical pain control using administrative claims data from a large health system: opioid-related adverse events and their impact on clinical and economic outcomes. Pharmacotherapy. 2013;33:383–391.PubMedCrossRef
17.
Zurück zum Zitat Lenart MJ, Wong K, Gupta RK, Mercaldo ND, Schildcrout JS, Michaels D, Malchow RJ. The impact of peripheral nerve techniques on hospital stay following major orthopedic surgery. Pain Med. 2012;13:828–834.PubMedCrossRef Lenart MJ, Wong K, Gupta RK, Mercaldo ND, Schildcrout JS, Michaels D, Malchow RJ. The impact of peripheral nerve techniques on hospital stay following major orthopedic surgery. Pain Med. 2012;13:828–834.PubMedCrossRef
18.
Zurück zum Zitat Lin E, Choi J, Hadzic A. Peripheral nerve blocks for outpatient surgery: evidence-based indications. Curr Opin Anaesthesiol. 2013;26:467–474.PubMed Lin E, Choi J, Hadzic A. Peripheral nerve blocks for outpatient surgery: evidence-based indications. Curr Opin Anaesthesiol. 2013;26:467–474.PubMed
19.
Zurück zum Zitat Lindenauer PK, Pekow P, Wang K, Mamidi DK, Gutierrez B, Benjamin EM. Perioperative beta-blocker therapy and mortality after major noncardiac surgery. N Engl J Med. 2005;353:349–361.PubMedCrossRef Lindenauer PK, Pekow P, Wang K, Mamidi DK, Gutierrez B, Benjamin EM. Perioperative beta-blocker therapy and mortality after major noncardiac surgery. N Engl J Med. 2005;353:349–361.PubMedCrossRef
20.
Zurück zum Zitat Liu SS, Gordon MA, Shaw PM, Wilfred S, Shetty T, Yadeau JT. A prospective clinical registry of ultrasound-guided regional anesthesia for ambulatory shoulder surgery. Anesth Analg. 2010;111:617–623.PubMedCrossRef Liu SS, Gordon MA, Shaw PM, Wilfred S, Shetty T, Yadeau JT. A prospective clinical registry of ultrasound-guided regional anesthesia for ambulatory shoulder surgery. Anesth Analg. 2010;111:617–623.PubMedCrossRef
21.
Zurück zum Zitat Memtsoudis SG, Sun X, Chiu YL, Nurok M, Stundner O, Pastores SM, Mazumdar M. Utilization of critical care services among patients undergoing total hip and knee arthroplasty: epidemiology and risk factors. Anesthesiology. 2012;117:107–116.PubMedCentralPubMedCrossRef Memtsoudis SG, Sun X, Chiu YL, Nurok M, Stundner O, Pastores SM, Mazumdar M. Utilization of critical care services among patients undergoing total hip and knee arthroplasty: epidemiology and risk factors. Anesthesiology. 2012;117:107–116.PubMedCentralPubMedCrossRef
22.
Zurück zum Zitat Memtsoudis SG, Sun X, Chiu YL, Stundner O, Liu SS, Banerjee S, Mazumdar M, Sharrock NE. Perioperative comparative effectiveness of anesthetic technique in orthopedic patients. Anesthesiology. 2013;118:1046–1058.PubMedCentralPubMedCrossRef Memtsoudis SG, Sun X, Chiu YL, Stundner O, Liu SS, Banerjee S, Mazumdar M, Sharrock NE. Perioperative comparative effectiveness of anesthetic technique in orthopedic patients. Anesthesiology. 2013;118:1046–1058.PubMedCentralPubMedCrossRef
23.
Zurück zum Zitat Merkow RP, Hall BL, Cohen ME, Dimick JB, Wang E, Chow WB, Ko CY, Bilimoria KY. Relevance of the c-statistic when evaluating risk-adjustment models in surgery. J Am Coll Surg. 2012;214:822–830.PubMedCrossRef Merkow RP, Hall BL, Cohen ME, Dimick JB, Wang E, Chow WB, Ko CY, Bilimoria KY. Relevance of the c-statistic when evaluating risk-adjustment models in surgery. J Am Coll Surg. 2012;214:822–830.PubMedCrossRef
24.
Zurück zum Zitat Pepe MS. The Statistical Evaluation of Medical Tests for Classification and Precision. Oxford, UK: Oxford University Press; 2003:66–94. Pepe MS. The Statistical Evaluation of Medical Tests for Classification and Precision. Oxford, UK: Oxford University Press; 2003:66–94.
26.
Zurück zum Zitat Rohrbaugh M, Kentor ML, Orebaugh SL, Williams B. Outcomes of shoulder surgery in the sitting position with interscalene nerve block: a single-center series. Reg Anesth Pain Med. 2013; 38:28–33.PubMedCrossRef Rohrbaugh M, Kentor ML, Orebaugh SL, Williams B. Outcomes of shoulder surgery in the sitting position with interscalene nerve block: a single-center series. Reg Anesth Pain Med. 2013; 38:28–33.PubMedCrossRef
27.
Zurück zum Zitat Shah A, Nielsen KC, Braga L, Pietrobon R, Klein SM, Steele SM. Interscalene brachial plexus block for outpatient shoulder arthroplasty: postoperative analgesia, patient satisfaction and complications. Indian J Orthop. 2007;41:230–236.PubMedCentralPubMedCrossRef Shah A, Nielsen KC, Braga L, Pietrobon R, Klein SM, Steele SM. Interscalene brachial plexus block for outpatient shoulder arthroplasty: postoperative analgesia, patient satisfaction and complications. Indian J Orthop. 2007;41:230–236.PubMedCentralPubMedCrossRef
28.
Zurück zum Zitat Sinha SK, Abrams JH, Barnett JT, Muller JG, Lahiri B, Bernstein BA, Weller RS. Decreasing the local anesthetic volume from 20 to 10 mL for ultrasound-guided interscalene block at the cricoid level does not reduce the incidence of hemidiaphragmatic paresis. Reg Anesth Pain Med. 2011;36:17–20.PubMedCrossRef Sinha SK, Abrams JH, Barnett JT, Muller JG, Lahiri B, Bernstein BA, Weller RS. Decreasing the local anesthetic volume from 20 to 10 mL for ultrasound-guided interscalene block at the cricoid level does not reduce the incidence of hemidiaphragmatic paresis. Reg Anesth Pain Med. 2011;36:17–20.PubMedCrossRef
29.
Zurück zum Zitat Stundner O, Chiu YL, Sun X, Mazumdar M, Fleischut P, Poultsides L, Gerner P, Fritsch G, Memtsoudis SG. Comparative perioperative outcomes associated with neuraxial versus general anesthesia for simultaneous bilateral total knee arthroplasty. Reg Anesth Pain Med. 2012;37:638–644.PubMedCentralPubMedCrossRef Stundner O, Chiu YL, Sun X, Mazumdar M, Fleischut P, Poultsides L, Gerner P, Fritsch G, Memtsoudis SG. Comparative perioperative outcomes associated with neuraxial versus general anesthesia for simultaneous bilateral total knee arthroplasty. Reg Anesth Pain Med. 2012;37:638–644.PubMedCentralPubMedCrossRef
30.
Zurück zum Zitat Sviggum HP, Jacob AK, Mantilla CB, Schroeder DR, Sperling JW, Hebl JR. Perioperative nerve injury after total shoulder arthroplasty: assessment of risk after regional anesthesia. Reg Anesth Pain Med. 2012;37:490–494.PubMedCrossRef Sviggum HP, Jacob AK, Mantilla CB, Schroeder DR, Sperling JW, Hebl JR. Perioperative nerve injury after total shoulder arthroplasty: assessment of risk after regional anesthesia. Reg Anesth Pain Med. 2012;37:490–494.PubMedCrossRef
31.
Zurück zum Zitat Tetzlaff JE, Yoon HJ, Brems J. Interscalene brachial plexus block for shoulder surgery. Reg Anesth. 1994;19:339–343.PubMed Tetzlaff JE, Yoon HJ, Brems J. Interscalene brachial plexus block for shoulder surgery. Reg Anesth. 1994;19:339–343.PubMed
32.
Zurück zum Zitat United States Department of Health and Human Services. OCR Privacy Brief: Summary of the HIPAA Privacy Rule. Washington, DC: Office for Civil Rights, HIPAA Compliance Assistance; 2003. United States Department of Health and Human Services. OCR Privacy Brief: Summary of the HIPAA Privacy Rule. Washington, DC: Office for Civil Rights, HIPAA Compliance Assistance; 2003.
33.
Zurück zum Zitat Urmey WF, Gloeggler PJ. Pulmonary function changes during interscalene brachial plexus block: effects of decreasing local anesthetic injection volume. Reg Anesth. 1993;18:244–249.PubMed Urmey WF, Gloeggler PJ. Pulmonary function changes during interscalene brachial plexus block: effects of decreasing local anesthetic injection volume. Reg Anesth. 1993;18:244–249.PubMed
34.
Zurück zum Zitat Urmey WF, Talts KH, Sharrock NE. One hundred percent incidence of hemidiaphragmatic paresis associated with interscalene brachial plexus anesthesia as diagnosed by ultrasonography. Anesth Analg. 1991;72:498–503.PubMedCrossRef Urmey WF, Talts KH, Sharrock NE. One hundred percent incidence of hemidiaphragmatic paresis associated with interscalene brachial plexus anesthesia as diagnosed by ultrasonography. Anesth Analg. 1991;72:498–503.PubMedCrossRef
35.
Zurück zum Zitat Verelst P, Van Zundert A. Respiratory impact of analgesic strategies for shoulder surgery. Reg Anesth Pain Med. 2013;38:50–53.PubMedCrossRef Verelst P, Van Zundert A. Respiratory impact of analgesic strategies for shoulder surgery. Reg Anesth Pain Med. 2013;38:50–53.PubMedCrossRef
36.
Zurück zum Zitat Wolfe JW, Butterworth JF. Local anesthetic systemic toxicity: update on mechanisms and treatment. Curr Opin Anaesthesiol. 2011;24:561–566.PubMedCrossRef Wolfe JW, Butterworth JF. Local anesthetic systemic toxicity: update on mechanisms and treatment. Curr Opin Anaesthesiol. 2011;24:561–566.PubMedCrossRef
Metadaten
Titel
Peripheral Nerve Blocks in Shoulder Arthroplasty: How Do They Influence Complications and Length of Stay?
verfasst von
Ottokar Stundner, MD
Rehana Rasul, MA, MPH
Ya-Lin Chiu, MS
Xuming Sun, MS
Madhu Mazumdar, MA, MS, PhD
Chad M. Brummett, MD
Reinhold Ortmaier, MD
Stavros G. Memtsoudis, MD, PhD, FCCP
Publikationsdatum
01.05.2014
Verlag
Springer US
Erschienen in
Clinical Orthopaedics and Related Research® / Ausgabe 5/2014
Print ISSN: 0009-921X
Elektronische ISSN: 1528-1132
DOI
https://doi.org/10.1007/s11999-013-3356-1

Weitere Artikel der Ausgabe 5/2014

Clinical Orthopaedics and Related Research® 5/2014 Zur Ausgabe

Reply to Letter to the Editor

Reply to Letter to the Editor

Symposium: Perioperative Pain Management in Orthopaedic Surgery

Association of Obesity With Inflammation and Pain After Total Hip Arthroplasty

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Proximale Humerusfraktur: Auch 100-Jährige operieren?

01.05.2024 DCK 2024 Kongressbericht

Mit dem demographischen Wandel versorgt auch die Chirurgie immer mehr betagte Menschen. Von Entwicklungen wie Fast-Track können auch ältere Menschen profitieren und bei proximaler Humerusfraktur können selbst manche 100-Jährige noch sicher operiert werden.

Sind Frauen die fähigeren Ärzte?

30.04.2024 Gendermedizin Nachrichten

Patienten, die von Ärztinnen behandelt werden, dürfen offenbar auf bessere Therapieergebnisse hoffen als Patienten von Ärzten. Besonders gilt das offenbar für weibliche Kranke, wie eine Studie zeigt.

Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

26.04.2024 Hüft-TEP Nachrichten

Ob bei einer Notfalloperation nach Schenkelhalsfraktur eine Hemiarthroplastik oder eine totale Endoprothese (TEP) eingebaut wird, sollte nicht allein vom Alter der Patientinnen und Patienten abhängen. Auch über 90-Jährige können von der TEP profitieren.

Arthroskopie kann Knieprothese nicht hinauszögern

25.04.2024 Gonarthrose Nachrichten

Ein arthroskopischer Eingriff bei Kniearthrose macht im Hinblick darauf, ob und wann ein Gelenkersatz fällig wird, offenbar keinen Unterschied.

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.