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Advances in Therapy
Erschienen in: Advances in Therapy 10/2021

15.09.2021 | Review

Pharmacotherapy for the Treatment of Gastric Antral Vascular Ectasia: A Narrative Review

verfasst von: Mengyuan Peng, Xiaozhong Guo, Fangfang Yi, Fernando Gomes Romeiro, Andrea Mancuso, Xingshun Qi

Erschienen in: Advances in Therapy | Ausgabe 10/2021

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Abstract

Gastric antral vascular ectasia (GAVE) is an uncommon clinical entity leading to recurrent gastrointestinal bleeding. There is no consensus regarding treatment of GAVE. Endoscopic therapy is the preferred treatment option, but has a fairly high recurrence rate. Surgical resection can completely resolve GAVE, but is invasive with a relatively high risk of postoperative complications. Recently, the role of pharmacotherapy for GAVE has been recognized. However, the evidence is limited to scattered case reports or small case series. This review comprehensively summarizes the efficacy and side effects of drugs commonly used for the treatment of GAVE, including octreotide, cyproheptadine, cyclophosphamide, prednisolone, estrogen-progesterone, thalidomide, bevacizumab, and tranexamic acid.
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Metadaten
Titel
Pharmacotherapy for the Treatment of Gastric Antral Vascular Ectasia: A Narrative Review
verfasst von
Mengyuan Peng
Xiaozhong Guo
Fangfang Yi
Fernando Gomes Romeiro
Andrea Mancuso
Xingshun Qi
Publikationsdatum
15.09.2021
Verlag
Springer Healthcare
Erschienen in
Advances in Therapy / Ausgabe 10/2021
Print ISSN: 0741-238X
Elektronische ISSN: 1865-8652
DOI
https://doi.org/10.1007/s12325-021-01912-6

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