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Quality of Life Research

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01.11.2013 | Commentary

Pitfalls in subgroup analysis based on growth mixture models: a commentary on van Leeuwen et al. (2012)

verfasst von: Cameron N. McIntosh

Erschienen in: Quality of Life Research | Ausgabe 9/2013

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Abstract

Objectives

This article is a brief commentary in response to “van Leeuwen et al. (Qual Life Res 21:1499–1508, 2012)”

Methods and results

The commentary argues that in the context of mixture modeling, assigning individuals to specific subgroups for conducting a secondary set of analyses ignores the original uncertainty in group membership, thereby biasing any subsequent results and inference.

Conclusions

Alternative approaches to subgroup analysis that attempt to preserve uncertainty in group membership are discussed and illustrated.

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Titel: Pitfalls in subgroup analysis based on growth mixture models: a commentary on van Leeuwen et al. (2012)
verfasst von: Cameron N. McIntosh
Publikationsdatum: 01.11.2013
Verlag: Springer Netherlands
Erschienen in: Quality of Life Research / Ausgabe 9/2013
Print ISSN: 0962-9343
Elektronische ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-013-0385-x

Springer Medizin

Abstract

Objectives

Methods and results

Conclusions

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