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International Archives of Occupational and Environmental Health

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16.09.2020 | Original Article

Prenatal exposure to ambient air pollution and adverse pregnancy outcomes in Ahvaz, Iran: a generalized additive model

verfasst von: Maryam Dastoorpoor, Narges Khanjani, Asghar Moradgholi, Reihaneh Sarizadeh, Maria Cheraghi, Fatemeh Estebsari

Erschienen in: International Archives of Occupational and Environmental Health | Ausgabe 2/2021

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Abstract

Objective

There is some evidence about the short-term effects of air pollutants on adverse pregnancy outcomes. The aim of this study was to determine the association between air pollutants and spontaneous abortion, stillbirth, gestational hypertension, preeclampsia, gestational diabetes and macrosomia in Ahvaz, which is one of the most polluted cities in the Middle East.

Methods

Data on adverse pregnancy outcomes and air pollutants including ozone (O₃), nitric oxide (NO), nitrogen dioxide (NO₂), sulfur dioxide (SO₂), carbon monoxide (CO), particles with a diameter of less than 10 µm (PM₁₀) and particles with a diameter less than 2.5 µm (PM_2.5) were inquired from the Health Department of Ahvaz Jundishapur University of Medical Sciences and the Environmental Protection Agency of Khuzestan Province for the years 2008–2018. A time series analysis using the generalized additive model (GAM) with up to 6-day lags was used.

Results

The results showed that the SO₂ pollutant on 0, 1, 3, 4, and 6-day lags and PM₁₀ on lag 0 had direct and significant associations with spontaneous abortion. NO, NO₂ and CO on 0–6-day lags, and O₃ on 6-day lags showed direct and significant associations with preeclampsia. NO and NO₂ pollutants showed significant and direct associations with gestational diabetes, during 0- and 6-day lags. NO on 0-, 3- and 4-day lags, CO in all 0–6-day lags and PM_2.5 on 1-, 3-, 5-, and 6-day lags showed direct and significant associations with macrosomia. None of the pollutants showed significant associations with stillbirth or gestational hypertension.

Conclusions

The results of this study suggest that some air pollutants are associated with spontaneous abortion, preeclampsia, gestational diabetes and macrosomia. This study further emphasizes the need to control ambient air pollution.

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Titel: Prenatal exposure to ambient air pollution and adverse pregnancy outcomes in Ahvaz, Iran: a generalized additive model
verfasst von: Maryam Dastoorpoor
Narges Khanjani
Asghar Moradgholi
Reihaneh Sarizadeh
Maria Cheraghi
Fatemeh Estebsari
Publikationsdatum: 16.09.2020
Verlag: Springer Berlin Heidelberg
Erschienen in: International Archives of Occupational and Environmental Health / Ausgabe 2/2021
Print ISSN: 0340-0131
Elektronische ISSN: 1432-1246
DOI: https://doi.org/10.1007/s00420-020-01577-8

Springer Medizin

Abstract

Objective

Methods

Results

Conclusions

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