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Erschienen in: Quality of Life Research 5/2018

08.02.2018

PROMIS depression measures perform similarly to legacy measures relative to a structured diagnostic interview for depression in cancer patients

verfasst von: Kerrie Clover, Sylvie D. Lambert, Christopher Oldmeadow, Benjamin Britton, Madeleine T. King, Alex J. Mitchell, Gregory Carter

Erschienen in: Quality of Life Research | Ausgabe 5/2018

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Abstract

Purpose

To assess the convergent validity of the Patient-Reported Outcomes Measurement Information System (PROMIS) depression measures relative to legacy measures and criterion validity against a structured diagnostic interview for depression in an oncology sample.

Methods

132 oncology/haematology outpatients completed the PROMIS Depression Computer Adaptive Test (PROMIS-D-CAT) and PROMIS Depression Short Form (PROMIS-D-SF) along with seven legacy measures: Beck Depression Inventory (BDI); Centre for Epidemiological Studies Depression (CES-D); Depression, Anxiety and Stress Scale; Hospital Anxiety and Depression Scale; Patient Health Questionnaire; Distress Thermometer and PSYCH-6. Correlations, area under the curve (AUC) and diagnostic accuracy statistics were calculated with Structured Clinical Interview as the gold standard.

Results

Both PROMIS measures correlated with all legacy measures at p < .001 (ρ = 0.589–0.810) and all AUCs (> 0.800) were comparable. At the cut-off points for mild depression of 53, the PROMIS measures had sensitivity (0.83 for PROMIS-D-CAT and 0.80 for PROMIS-D-SF) similar to or better than 6/7 legacy measures with high negative predictive value (> 90%). At cut-off points of 60 for moderate depression, PROMIS measures had specificity > 90%, similar to or better than all legacy measures and positive predictive value ≥ 0.50 (similar to 5/7 legacy measures).

Conclusions

The convergent and criterion validity of the PROMIS depression measures in cancer populations was confirmed, although the optimal cut-off points are not established. PROMIS measures were briefer than BDI-II and CES-D but do not offer any advance in terms of diagnostic accuracy, reduced response burden or cost over other legacy measures of depression in oncology patients.
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Metadaten
Titel
PROMIS depression measures perform similarly to legacy measures relative to a structured diagnostic interview for depression in cancer patients
verfasst von
Kerrie Clover
Sylvie D. Lambert
Christopher Oldmeadow
Benjamin Britton
Madeleine T. King
Alex J. Mitchell
Gregory Carter
Publikationsdatum
08.02.2018
Verlag
Springer International Publishing
Erschienen in
Quality of Life Research / Ausgabe 5/2018
Print ISSN: 0962-9343
Elektronische ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-018-1803-x

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