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Erschienen in: European Spine Journal 5/2019

02.01.2019 | Original Article

Quantitative magnetic resonance imaging assessment of lateral atlantoaxial joint meniscoid composition: a validation study

verfasst von: Scott F. Farrell, Peter Stanwell, Jon Cornwall, Peter G. Osmotherly

Erschienen in: European Spine Journal | Ausgabe 5/2019

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Abstract

Purpose

Lateral atlantoaxial (LAA) joint meniscoid composition may have clinical significance in patients following neck trauma. However, the existing method of radiologically assessing meniscoid composition has an inherent element of subjectivity, which could contribute to measurement variability. The present study sought to investigate the accuracy of two-point Dixon fat/water separation MRI as a quantitative assessment of LAA joint meniscoid composition.

Methods

Sixteen LAA joint meniscoids were excised from four cadavers (mean [SD] age 79.5 [3.7] years; one female) following cervical spine MRI (two-point Dixon, T1-weighted VIBE and T2-weighted SPACE sequences). Composition of LAA joint meniscoids was undertaken by (1) histological examination by light microscopy, (2) calculation of fat fraction by Dixon MRI (both in-phase/opposed-phase and fat/water methods), and (3) the existing method of considering VIBE and SPACE signal intensities. Analysis was performed using the kappa statistic with linear weighting.

Results

Microscopy revealed three, five, and eight meniscoids to be composed of adipose, fibroadipose, and fibrous tissues, respectively. Dixon sequence MRI classified 11 of these meniscoids correctly, with ‘substantial’ level of agreement (In-phase/Opp-phase kappa statistic = 0.78 [95% CI 0.38, 1.17]; fat/water kappa statistic = 0.72 [95% CI 0.32, 1.11]). Level of agreement between microscopy and the VIBE and SPACE method was ‘slight’ (kappa statistic = 0.02 [95% CI − 0.34, 0.38]).

Conclusions

Findings suggest that Dixon fat/water separation MRI may have superior utility in the assessment of LAA joint meniscoid composition than the existing method of considering VIBE and SPACE signal intensities.

Graphical abstract

These slides can be retrieved under Electronic Supplementary Material.
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Metadaten
Titel
Quantitative magnetic resonance imaging assessment of lateral atlantoaxial joint meniscoid composition: a validation study
verfasst von
Scott F. Farrell
Peter Stanwell
Jon Cornwall
Peter G. Osmotherly
Publikationsdatum
02.01.2019
Verlag
Springer Berlin Heidelberg
Erschienen in
European Spine Journal / Ausgabe 5/2019
Print ISSN: 0940-6719
Elektronische ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-018-05868-0

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