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Erschienen in: Cardiovascular Toxicology 1/2019

13.08.2018

Refractory Arrhythmias in a Young Patient Poisoned by Imipramine

verfasst von: Nahid Azdaki, Samaneh Nakhaee, Nasim Zamani, Omid Mehrpour

Erschienen in: Cardiovascular Toxicology | Ausgabe 1/2019

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Abstract

Tricyclic antidepressants are used to treat a variety of mental disorders, and are considered a common cause of fatal drug poisoning. This study reports a young woman with no history of cardiac diseases who presented to the emergency department with heart palpitation, weakness, and lethargy. After a short period of time, she became unconscious and experienced hypotension and refractory arrhythmia, finally being diagnosed with imipramine poisoning. Accurate history taking and the possible causes of these complications including cardio-toxic drug poisoning should be considered in such patients.
Literatur
1.
Zurück zum Zitat Marland, G., Snowden, A., McNay, L., McCaig, M., & Boyd, G. (2011) Tricyclic antidepressant self-poisoning and admission for acute care. British Journal of Cardiac Nursing, 6(12), 589–596.CrossRef Marland, G., Snowden, A., McNay, L., McCaig, M., & Boyd, G. (2011) Tricyclic antidepressant self-poisoning and admission for acute care. British Journal of Cardiac Nursing, 6(12), 589–596.CrossRef
2.
Zurück zum Zitat Sahraeizadeh, A. (2016). Impending cardiogenic shock due to tricyclic antidepressant toxicity, computed tomography findings; a case report. Health Sciences, 5(8), 264–266. Sahraeizadeh, A. (2016). Impending cardiogenic shock due to tricyclic antidepressant toxicity, computed tomography findings; a case report. Health Sciences, 5(8), 264–266.
3.
Zurück zum Zitat Amiri, H., Zamani, N., Hassanian-Moghaddam, H., & Shadnia, S. (2016). Cardiotoxicity of tricyclic antidepressant treated by 2650 mEq sodium bicarbonate: A case report. JRSM Cardiovascular Disease, 5, 2048004016682178.CrossRefPubMedPubMedCentral Amiri, H., Zamani, N., Hassanian-Moghaddam, H., & Shadnia, S. (2016). Cardiotoxicity of tricyclic antidepressant treated by 2650 mEq sodium bicarbonate: A case report. JRSM Cardiovascular Disease, 5, 2048004016682178.CrossRefPubMedPubMedCentral
4.
Zurück zum Zitat Moradi, M., Ghaemi, K., & Mehrpour, O. (2016). A hospital base epidemiology and pattern of acute adult poisoning across Iran: A systematic review. Electronic Physician, 8(9), 2860.CrossRefPubMedPubMedCentral Moradi, M., Ghaemi, K., & Mehrpour, O. (2016). A hospital base epidemiology and pattern of acute adult poisoning across Iran: A systematic review. Electronic Physician, 8(9), 2860.CrossRefPubMedPubMedCentral
5.
Zurück zum Zitat Alinejad, S., Zamani, N., Abdollahi, M., & Mehrpour, O. (2017) A narrative review of acute adult poisoning in Iran. Iranian Journal of Medical Sciences, 41(2), 327–346. Alinejad, S., Zamani, N., Abdollahi, M., & Mehrpour, O. (2017) A narrative review of acute adult poisoning in Iran. Iranian Journal of Medical Sciences, 41(2), 327–346.
6.
Zurück zum Zitat Taghaddosinejad, F., Sheikhazadi, A., Yaghmaei, A., Mehrpour, O., & Schwake, L. (2012). Epidemiology and treatment of severe poisoning in the intensive care unit: Lessons from a One-year prospective observational study. The Journal of Clinical Toxicology, 1, 2161–2495. Taghaddosinejad, F., Sheikhazadi, A., Yaghmaei, A., Mehrpour, O., & Schwake, L. (2012). Epidemiology and treatment of severe poisoning in the intensive care unit: Lessons from a One-year prospective observational study. The Journal of Clinical Toxicology, 1, 2161–2495.
7.
Zurück zum Zitat Kane, M. D., Kathleen, E., Kane, M. D., Bryan, G., Pierog, D. O., Jessica, E., Donovan, J. W., & Helmick, R. N. (2009). Tricyclic antidepressant toxicity treated with massive sodium bicarbonate. The American Journal Of Emergency Medicine, 27(9), 3.CrossRef Kane, M. D., Kathleen, E., Kane, M. D., Bryan, G., Pierog, D. O., Jessica, E., Donovan, J. W., & Helmick, R. N. (2009). Tricyclic antidepressant toxicity treated with massive sodium bicarbonate. The American Journal Of Emergency Medicine, 27(9), 3.CrossRef
8.
Zurück zum Zitat Lee, A., & Pickham, D. (2016) Basic cardiac electrophysiology and common drug-induced arrhythmias. Critical Care Nursing Clinics of North America, 28(3):357–371.CrossRefPubMed Lee, A., & Pickham, D. (2016) Basic cardiac electrophysiology and common drug-induced arrhythmias. Critical Care Nursing Clinics of North America, 28(3):357–371.CrossRefPubMed
9.
Zurück zum Zitat Nada, A., Gintant, G. A., Kleiman, R., Gutstein, D. E., Gottfridsson, C., Michelson, E. L., et al. (2013). The evaluation and management of drug effects on cardiac conduction (PR and QRS intervals) in clinical development. American Heart Journal, 165(4), 489–500.CrossRefPubMed Nada, A., Gintant, G. A., Kleiman, R., Gutstein, D. E., Gottfridsson, C., Michelson, E. L., et al. (2013). The evaluation and management of drug effects on cardiac conduction (PR and QRS intervals) in clinical development. American Heart Journal, 165(4), 489–500.CrossRefPubMed
10.
Zurück zum Zitat Teply, R. M., Packard, K. A., White, N. D., Hilleman, D. E., & DiNicolantonio, J. J. (2016). Treatment of depression in patients with concomitant cardiac disease. Progress in Cardiovascular Diseases, 58(5), 514–528.CrossRefPubMed Teply, R. M., Packard, K. A., White, N. D., Hilleman, D. E., & DiNicolantonio, J. J. (2016). Treatment of depression in patients with concomitant cardiac disease. Progress in Cardiovascular Diseases, 58(5), 514–528.CrossRefPubMed
11.
Zurück zum Zitat Buckley, N. A., Chevalier, S., Leditschke, I. A., O’Connell, D. L., Leitch, J., & Pond, S. M. (2003). The limited utility of electrocardiography variables used to predict arrhythmia in psychotropic drug overdose. Critical Care, 7(5), R101.CrossRefPubMedPubMedCentral Buckley, N. A., Chevalier, S., Leditschke, I. A., O’Connell, D. L., Leitch, J., & Pond, S. M. (2003). The limited utility of electrocardiography variables used to predict arrhythmia in psychotropic drug overdose. Critical Care, 7(5), R101.CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat Sanaei-Zadeh, H., & Toussi, A. G. (2011). Resolution of wide complex tachycardia after administration of hypertonic sodium bicarbonate in a patient with severe tricyclic antidepressant poisoning. Resuscitation, 82(6), 792–793.CrossRefPubMed Sanaei-Zadeh, H., & Toussi, A. G. (2011). Resolution of wide complex tachycardia after administration of hypertonic sodium bicarbonate in a patient with severe tricyclic antidepressant poisoning. Resuscitation, 82(6), 792–793.CrossRefPubMed
13.
Zurück zum Zitat Sabah, K. M., Chowdhury, A. W., Islam, M. S., Saha, B. P., Kabir, S. R., & Kawser, S. (2017). Amitriptyline-induced ventricular tachycardia: A case report. BMC Research Notes, 10(1), 286.CrossRefPubMedPubMedCentral Sabah, K. M., Chowdhury, A. W., Islam, M. S., Saha, B. P., Kabir, S. R., & Kawser, S. (2017). Amitriptyline-induced ventricular tachycardia: A case report. BMC Research Notes, 10(1), 286.CrossRefPubMedPubMedCentral
14.
Zurück zum Zitat Wu, C. S., Tsai, Y. T., Hsiung, C. A., & Tsai, H. J. (2017). Comparative risk of ventricular arrhythmia and sudden cardiac death across antidepressants in patients with depressive disorders. Journal of Clinical Psychopharmacology, 37(1), 32–39.CrossRefPubMed Wu, C. S., Tsai, Y. T., Hsiung, C. A., & Tsai, H. J. (2017). Comparative risk of ventricular arrhythmia and sudden cardiac death across antidepressants in patients with depressive disorders. Journal of Clinical Psychopharmacology, 37(1), 32–39.CrossRefPubMed
Metadaten
Titel
Refractory Arrhythmias in a Young Patient Poisoned by Imipramine
verfasst von
Nahid Azdaki
Samaneh Nakhaee
Nasim Zamani
Omid Mehrpour
Publikationsdatum
13.08.2018
Verlag
Springer US
Erschienen in
Cardiovascular Toxicology / Ausgabe 1/2019
Print ISSN: 1530-7905
Elektronische ISSN: 1559-0259
DOI
https://doi.org/10.1007/s12012-018-9477-8

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