nach oben

Osteoporosis International

Erschienen in:

01.07.2008 | Original Article

Relationship between mandibular inferior cortex and general bone metabolism in older adults

Erschienen in: Osteoporosis International | Ausgabe 7/2008

Einloggen, um Zugang zu erhalten

Abstract

Summary

The purpose of this study was to investigate whether a link exists between the jawbone and general bone metabolism. The results of our study indicate that a mandibular inferior cortical erosion finding on dental panoramic radiographs is significantly associated with increased biochemical markers of bone turnover.

Introduction

The purpose of this study was to investigate whether a link exists between the jawbone and general bone metabolism.

Methods

We measured values of serum bone-specific alkaline phosphatase (S-BAP) and urinary N-telopeptide cross-links of type I collagen (U-NTX). To evaluate the jawbone, we used mandibular inferior cortex (MIC) classification on dental panoramic radiographs. After 134 subjects were divided into three groups (C1: normal cortex, C2: mildly to moderately eroded cortex, C3: severely eroded cortex), we evaluated the relationship between S-BAP or U-NTX and MIC classification by Scheffe’s multiple comparison test.

Results

A significant correlation was found between MIC classification and S-BAP (C1 vs. C2: p < 0.01, C1 vs. C3: p < 0.01, C2 vs. C3: NS). A significant correlation was found between MIC classification and U-NTX (C1 vs. C2: p < 0.01, C1 vs. C3: p < 0.001, C2 vs. C3: p < 0.01).

Conclusions

The results of our study indicate that the mandibular inferior cortical erosion finding on dental panoramic radiographs is significantly associated with increased S-BAP and U-NTX levels. We suggest that there is an association between the jawbone and general bone metabolism.

Klemetti E, Vainio P, Lassila V et al (1993) Cortical bone mineral density in the mandible and osteoporosis status in postmenopausal women. Scand J Dent Res 101:219–223PubMed

Taguchi A, Tanimoto K, Suei Y et al (1996) Relationship between the mandibular and lumbar vertebral bone mineral density at different postmenopausal stages. Dentomaxillofac Radiol 25:130–135PubMed

Horner K, Devlin H, Alsop CW et al (1996) Mandibular bone mineral density as a predictor of skeletal osteoporosis. Br J Radiol 69:1019–1025PubMedCrossRef

Tezal M, Wactawski-Wende J, Grossi SG et al (2000) The relationship between bone mineral density and periodontitis in postmenopausal women. J Periodontol 71:1492–1498PubMedCrossRef

Hildebolt CF, Pilgram TK, Yokoyama-Crothers N et al (2000) Alveolar bone height and postcranial bone mineral density: negative effects of cigarette smoking and parity. J Periodontol 71:683–689PubMedCrossRef

Wactawski-Wende J, Hausmann E, Hovey K et al (2005) The association between osteoporosis and alveolar crestal height in postmenopausal women. J Periodontol 76:2116–2124PubMedCrossRef

Kribbs PJ (1990) Comparison of mandibular bone in normal and osteoporotic women. J Prosthet Dent 63:218–222PubMedCrossRef

Lundstrom A, Jendle J, Stenstrom B et al (2001) Periodontal conditions in 70 year-old women with osteoporosis. Swed Dent J 25:89–96PubMed

Ross PD, Kress BC, Parson RE et al (2000) Serum bone alkaline phosphatase and calcaneus bone density predict fractures: a prospective study. Osteoporos Int 11:76–82PubMedCrossRef

10.

Garnero P, Sornay-Rendu E, Duboeuf F et al (1999) Markers of bone turnover predict postmenopausal forearm bone loss over 4 years: the OFELY study. J Bone Miner Res 14:1614–1621PubMedCrossRef

11.

Garnero P, Sornay-Rendu E, Claustrat B et al (2000) Biochemical markers of bone turnover, endogenous hormones and the risk of fractures in postmenopausal women: the OFELY study. J Bone Miner Res 15:1526–1536PubMedCrossRef

12.

Chaki O, Yoshikata I, Kikuchi R et al (2000) The predictive value of biochemical markers of bone turnover for bone mineral density in postmenopausal Japanese women. J Bone Miner Res 15:1537–1544PubMedCrossRef

13.

Iki M, Akiba T, Matsumoto T et al (2004) Reference database of biochemical markers of bone turnover for the Japanese female population. Japanese Population-based Osteoporosis (JPOS) Study. Osteoporos Int 15:981–991PubMedCrossRef

14.

Klemetti E, Kolmakov S, Kroger H (1994) Pantomography in assessment of the osteoporosis risk group. Scand J Dent Res 102:68–72PubMed

15.

Taguchi A, Suei Y, Ohtsuka M et al (1996) Usefulness of panoramic radiography in the diagnosis of postmenopausal osteoporosis in women. Width and morphology of inferior cortex of the mandible. Dentomaxillofac Radiol 25:263–267PubMed

16.

Nakamoto T, Taguchi A, Ohtsuka M et al (2003) Dental panoramic radiograph as a tool to detect postmenopausal women with low bone mineral density: untrained general dental practitioners’ diagnostic performance. Osteoporos Int 14:659–664PubMedCrossRef

17.

Halling A, Persson GR, Berglund J et al (2005) Comparison between the Klemetti index and heel DXA BMD measurements in the diagnosis of reduced skeletal bone mineral density in the elderly. Osteoporos Int 16:999–1003PubMedCrossRef

18.

Taguchi A, Tsuda M, Ohtsuka M et al (2006) Use of dental panoramic radiographs in identifying younger postmenopausal women with osteoporosis. Osteoporos Int 17:387–394PubMedCrossRef

19.

Taguchi A, Tanimoto K, Suei Y (1993) The estimation of the radiomorphometric indices of the mandible using panoramic radiography. Dent Radiol 33:309–316 (in Japanese)

20.

Genant HK, Wu CY, van Kuijk C et al (1993) Vertebral fracture assessment using a semiquantitative technique. J Bone Miner Res 8:1137–1148PubMed

21.

Hans D, Hartl F, Krieg MA (2003) Device-specific weighted T-score for two quantitative ultrasounds: operational propositions for the management of osteoporosis for 65 years and older women in Switzerland. Osteoporos Int 14:251–258PubMed

22.

Krieg MA, Cornuz J, Ruffieux C et al (2006) Prediction of hip fracture risk by quantitative ultrasound in more than 7000 Swiss women > or =70 years of age: comparison of three technologically different bone ultrasound devices in the SEMOF study. J Bone Miner Res 21:1457–1463PubMedCrossRef

23.

Tateiwa Y, Nakatsuchi Y, Tsuchigane A et al (2002) Discriminatory ability of quantitative ultrasound parameters and bone mineral density in elderly Japanese women with hip fracture. Osteoporos Int 13(Suppl 2):S2

24.

Klemetti E, Kolmakov S (1997) Morphology of the mandibular cortex on panoramic radiographs as an indicator of bone quality. Dentomaxillofac Radiol 26:22–25PubMedCrossRef

25.

Japan Osteoporosis Society (2004) Osteoporosis Jpn 12:191–207 (in Japanese)

26.

Stein GS, Lian JB, Qwen TA (1990) Relationship of cell growth to the regulation of tissue-specific gene expression during osteoblast differentiation. FASEB J 4:3111–3123PubMed

27.

Hanson DA, Weis MA, Bollen A-M et al (1992) A specific immunoassay for monitoring human bone resorption: quantitation of type I collagen cross-linked N-telopeptides in urine. J Bone Miner Res 7:1251–1258PubMedCrossRef

28.

Taguchi A, Sanada M, Krall E et al (2003) Relationship between dental panoramic radiographic findings and biochemical markers of bone turnover. J Bone Miner Res 18:1689–1694PubMedCrossRef

29.

Bollen A-M, Taguchi A, Hujoel PP et al (2000) Case-Control study on self-reported osteoporotic fractures and mandibular cortical bone. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 90:518–524PubMed

30.

Taguchi A, Ohtsuka M, Nakamoto T et al (2007) Identification of post-menopausal women at risk of osteoporosis by trained general dental practitioners using panoramic radiographs. Dentomaxillofac Radiol 36:149–154PubMedCrossRef

31.

Shimano T, Suzuki Y, Sasaki T (2002) Long-term trend of dental radiographic examination in Japan—analysis on health insurance data. Dent Radiol 42:9–21 (in Japanese)

32.

American Dental Association Survey Center (2000) 2000 survey of dental practice: characteristics of dentists in private practice and their patients. Chicago, IL

33.

Tugnait ACV, Hirschmann PN (2003) Radiographic equipment and techniques used in general dental practice: a survey of general dental practitioners in England and Wales. J Dent 31:197–203PubMedCrossRef

Titel: Relationship between mandibular inferior cortex and general bone metabolism in older adults
Publikationsdatum: 01.07.2008
Erschienen in: Osteoporosis International / Ausgabe 7/2008
Print ISSN: 0937-941X
Elektronische ISSN: 1433-2965
DOI: https://doi.org/10.1007/s00198-007-0526-6

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen.
» Jetzt entdecken

Neu im Fachgebiet Orthopädie und Unfallchirurgie

26.04.2024 | Hüft-TEP | Nachrichten

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Springer Medizin

Relationship between mandibular inferior cortex and general bone metabolism in older adults

Abstract

Summary

Introduction

Methods

Results

Conclusions

Arthropedia

Neu im Fachgebiet Orthopädie und Unfallchirurgie

Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

Arthroskopie kann Knieprothese nicht hinauszögern

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

Ärztliche Empathie hilft gegen Rückenschmerzen

Update Orthopädie und Unfallchirurgie

Springer Medizin

Abstract

Summary

Introduction

Methods

Results

Conclusions

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 7/2008

Patients’ preferences for osteoporosis drug treatment: a discrete choice experiment

Fall-related self-efficacy, not balance and mobility performance, is related to accidental falls in chronic stroke survivors with low bone mineral density

Monthly dosing of 75 mg risedronate on 2 consecutive days a month: efficacy and safety results

Effects of teriparatide on serum calcium in postmenopausal women with osteoporosis previously treated with raloxifene or alendronate

Protective effect of green tea polyphenols on bone loss in middle-aged female rats

Osteonectin/SPARC polymorphisms in Caucasian men with idiopathic osteoporosis

Arthropedia

Neu im Fachgebiet Orthopädie und Unfallchirurgie

Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

Arthroskopie kann Knieprothese nicht hinauszögern

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

Ärztliche Empathie hilft gegen Rückenschmerzen

Update Orthopädie und Unfallchirurgie