Erschienen in:
01.12.2008 | Author's Reply
Reply to the letter to the editor of João Luiz Pinheiro Franco
verfasst von:
Per Kjaer, Tom Bendix, Tue Secher Jensen, Lars Korsholm, Joan Solgaard Sorensen, Charlotte Leboeuf-Yde
Erschienen in:
European Spine Journal
|
Ausgabe 12/2008
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Excerpt
We would like to express our appreciation of the comments to our paper “Modic changes (MC) and their associations with clinical findings” [
10]. In our paper, we compare several clinical findings in people with Modic Changes and Disc Degeneration, degeneration only and no MRI findings. The main suggestion in the letter is that Modic Type 1 and Type 2 are different in relation to histopathological findings and should therefore be treated as two distinct subgroups in future studies (REF letter). We do agree with this notion. In our analyses we did not find statistically significant differences and, therefore, we did not report Modic Type 1 and 2 separately. However, in relation to the clinical picture (association with low back pain (LBP)), the distinction between different types of MC is challenging. Several factors such as classification of MC, observer variability and the clinical outcomes could influence the reporting of Modic changes and thus affect the results of the studies. …
