Background
Methods
REPRISE development
Purpose and context
Identify the need for a guideline
Generating reporting items for the candidate checklist
Pilot testing the checklist
REPRISE framework: content and rationale
No | Item | Descriptor and/or examples |
---|---|---|
A | Context and scope | |
1 | Define geographical scope | Global, regional, national, city, local area, institutional/organizational level, health service |
2 | Define health area, field, focus | Disease or condition specific, interventions, healthcare delivery, health system |
3 | Define the intended beneficiaries | This may include the general population or a specific population based on demographic (age, gender), clinical (disease, condition), or other characteristics who may benefit from the research |
4 | Define the target audience of the priorities | Policy makers, funders, researchers, industry or others who have the potential to implement the priorities identified |
5 | Identify the research area | Public health, health services research, clinical research, basic science |
6 | Identify the type of research questions | Etiology, diagnosis, prevention, treatment (interventions), prognosis, health services, psychosocial, behavioral and social science, economic evaluation, implementation; this may not be pre-defined |
7 | Define the time frame | Interim, short-term, long-term priorities, plans to revise and update |
B | Governance and team | |
8 | Describe the selection and structure of the leadership and management team | Those responsible for initiating, developing, and guiding the process for priority setting, and examples of structures include; Steering Committee, Advisory Group, Technical Experts |
9 | Describe the characteristics of the team | Stakeholder group or role, institutional affiliations, country or region, demographics (e.g. age sex), discipline, experience, expertise |
10 | Describe any training or experience relevant to conducting priority setting | Consultants or advisors, members with experience or skills relevant to the conducting priority-setting e.g. qualitative methods, surveys, facilitation |
C | Framework for priority setting | |
11 | State the framework used (if any) | James Lind Alliance, COHRED, CHNRI, Dialogue Model, no framework (general research priority setting) |
D | Stakeholders or participants | |
12 | Define the inclusion criteria for stakeholders involved in priority-setting | Patients, caregivers, general community, health professionals, researchers, policy makers, non-governmental organizations, government, industry; specific groups including vulnerable and marginalized populations |
13 | State the strategy or method for identifying and engaging stakeholders | Partnership with organizations, social media, recruitment through hospitals |
14 | Indicate the number of participants and/or organizations involved | Number of individuals and organizations, include number by stakeholder group |
15 | Describe the characteristics of stakeholders | Stakeholder group, demographic characteristics, areas of interest and expertise, discipline, affiliations |
16 | State if reimbursement for participation was provided | Cash, vouchers, certificates, acknowledgement; what purpose e.g. travel, accommodation, honorarium |
E | Identification and collection of research priorities | |
17 | Describe methods for collecting initial priorities | Methods e.g. Delphi survey, surveys, nominal group technique, interviews, focus groups, meetings, workshops; prioritization e.g. voting, ranking; mode e.g. face-to-face, online; may be informed by evidence e.g. systematic reviews, reviews of guidelines/other documents, health technology assessment |
18 | Describe methods for collating and categorizing priorities | Taxonomy or other framework used to organize, summarise, and aggregate topics or questions |
19 | Describe methods and reasons for modifying (removing, adding, reframing) priorities | Based on scope, clarity, definition, duplication, other criteria |
20 | Describe methods for refining or translating priorities into research topics or questions | Reviewed by Steering Committee or project team |
21 | Describe methods for checking whether research questions or topics have been answered | Systematic reviews, evidence mapping, consultation with experts |
22 | Describe number of research questions or topics | Number of priorities at each stage of the process |
F | Prioritization of research topics/questions | |
23 | Describe methods and criteria for prioritizing research topics or questions | Methods e.g. Delphi survey, surveys, nominal group technique, interviews, focus groups, meetings, workshops; Prioritization e.g. voting, ranking; Mode e.g. face-to-face, online; Criteria e.g. need, feasibility, novelty, equity |
24 | State the method or threshold for excluding research topics/questions | Thresholds for ranking scores, proportions, votes; other criteria |
G | Output | |
25 | State the approach to formulating the research priorities | Area, topic, questions, PICO (population, intervention, comparator, outcome) |
H | Evaluation and feedback | |
26 | Describe how the process of prioritization was evaluated | Survey, workshop |
27 | Describe how priorities were fed back to stakeholders and/or to the public; and how feedback (if received) was addressed and integrated | Public meetings or workshop, newsletters, website, email, online presentations |
I | Implementation | |
28 | Outline the strategy or action plans for implementing priorities | Communication with target audience, via policies and funding |
29 | Describe plans, strategies, or suggestions to evaluate impact | Integration in decision-making, funding allocation, review of relevant documents |
J | Funding and conflict of interest | |
30 | State sources of funding | Name sources of funding for the priority-setting exercise; if relevant include the budget and/or cost |
31 | Declare any conflicts or competing interests | State any conflicts of interest that may be at an individual level and/or at a contextual level (e.g. political issues, controversies) that may affect the process, output or implementation. |
Context and scope (items 1–7)
Governance and team (items 8–10)
Framework for priority setting (item 11)
Framework | Year | Organizationa | Countrya | Principles/values/ characteristics | Stakeholders | Scope | Outline of process | Output |
---|---|---|---|---|---|---|---|---|
James Lind Alliance (JLA) [5] | 2004 | National Institute for Health Research (NIHR) | UK | Partnership | Patients, caregivers, clinicians | Diagnosis, intervention, care and support | Gather priorities (survey) Process and verify Conduct Interim priority setting (survey) Conduct final priority setting (workshops using nominal group technique) | Top 10 research questions for funders |
Council on Health Research for Development Essential National Health Research (COHRED/ENHR) [39] | 2000 | Council on Health Research for Development | International | Inclusivity, involvement of a broad range of stakeholders, multidisciplinary and cross-sectorial, partnership, participatory and transparent, systematic analysis of health needs, societal and professional expectations | Researchers, decision-makers, health service providers, communities | – | Establish criteria Identify research areas (brainstorming, voting, nominal group technique, roundtable etc) Score against criteria (survey) | – |
2007 | Global Forum for Health Research | International | Systematic, fair, transparent | Investors in health research, researchers, general public | Fundamental, translation, implementation | Discuss criteria Select useful and important criteria Score against criteria (survey) Elicit stakeholder input (reference group) Adjust scores with stakeholder input | – | |
Dialogue Model [36] | 2007 | VU University | The Netherlands | Participatory, respect for experiential knowledge, dialogue between different stakeholders, emergent and flexible design | Patients, researchers, health professionals | Explore (informal discussion) Consult (separate stakeholder consultations, focus groups, interviews, other methods) Prioritize (survey, focus group, Delphi technique) Integrate (meeting) | – |