Background
Methods
Data source
Study design
Follow-up
Statistical analysis
The primary analysis
Re-sampling analysis
Accuracy rate testing
Results
Patient characteristics
The primary analysis
Infection group (n = 28) | Un-infection group (n = 4931) | P value | |
---|---|---|---|
Male, N (%) | 22 (78.6%) | 2606 (52.8%) | 0.007 |
Female, N (%) | 6 (21.4%) | 2325 (47.2%) | 0.007 |
Age (yrs), mean ± SD | 65.5 ± 12.2 | 71.3 ± 14.2 | 0.178 |
Diabetes, n (%) | 5 (17.9%) | 951 (19.3%) | 0.848 |
Pre-operation antibiotics, n (%) | 26 (92.9%) | 4754 (96.4%) | 0.619 |
Post-operation antibiotics, n (%) | 26 (92.9%) | 4754 (96.4%) | 0.619 |
Replacement procedure, n(%) | 15 (53.6%) | 1136 (23.0%) | 0.001 |
Post-operation fever, n(%) | 4 (14.3%) | 414 (8.4%) | 0.437 |
ICD, n(%) | 2 (7.1%) | 644 (13.1%) | 0.518 |
Clinical variables (Group I & Group II ) | Group I | Group II | P value |
---|---|---|---|
n (total,%) | n (total,%) | ||
Gender (male & female) | 22 (2628,0.8) | 6 (2331, 0.3) | 0.007 |
Post-operation fever (yes & no) | 4 (418,1.0) | 24 (4541,0.5) | 0.437 |
Antibiotics (yes & no) | 26 (4819,0.5) | 2 (140,1.4) | 0.417 |
Device type (pacemaker & ICD) | 26 (4313,0.6) | 2 (646,0.3) | 0.518 |
Type of procedure (primary & replacement) | 13 (3705,0.4) | 15 (1254,1.2) | 0.001 |
Variables | Β | SE | OR | 95%CI | P value |
---|---|---|---|---|---|
Age | 0.031 | 0.011 | 1.032 | 1.010–1.054 | 0.004 |
gender | 1.254 | 0.365 | 3.503 | 1.712–7.169 | 0.001 |
replacement procedure | −2.735 | 0.361 | 0.065 | 0.032--0.132 | 0.000 |
antibiotics | −1.386 | 0.632 | 0.250 | 0.72–0.863 | 0.028 |
The re-sampling analysis
Infection group (n = 123) | Un-infection group (n = 616) | P value | |
---|---|---|---|
Male, N (%) | 96 (78.0%) | 303 (49.2%) | 0.001 |
Female, N (%) | 27 (22.0%) | 313 (50.8%) | 0.001 |
Age (yrs), mean ± SD | 67.3 ± 11.4 | 73.9 ± 11.3 | 0.001 |
Diabetes, n (%) | 18 (16.7%) | 90 (19.3%) | 0.995 |
Pre-operation antibiotics, n (%) | 115 (93.5%) | 616 (100%) | 0.001 |
Post-operation antibiotics, n (%) | 115 (93.5%) | 616 (100%) | 0.001 |
Replacement procedure, n(%) | 52 (42.3%) | 450 (73.1%) | 0.001 |
Post-operation fever, n(%) | 18 (14.6%) | 41 (6.7%) | 0.003 |
ICD, n(%) | 8 (6.5%) | 20 (3.2%) | 0.142 |
Variables | Β | SE | OR | 95%CI | P value |
---|---|---|---|---|---|
Age | 0.040 | 0.013 | 1.041 | 1.015–1.067 | 0.002 |
gender | 1.429 | 0.475 | 4.176 | 1.647–10.590 | 0.003 |
replacement procedure | −2.498 | 0.394 | 0.082 | 0.038–0.178 | 0.000 |
antibiotics | −23.263 | 13,197 | 0.000 | 0.000–0.000 | 0.999 |