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Journal of Interventional Cardiac Electrophysiology

Erschienen in:

30.07.2018

Safety and efficacy of atrial fibrillation ablation guided by Ablation Index module

verfasst von: Francesco Solimene, Vincenzo Schillaci, Gergana Shopova, Francesco Urraro, Alberto Arestia, Assunta Iuliano, Fabio Maresca, Alessia Agresta, Vincenzo La Rocca, Antonio De Simone, Giuseppe Stabile

Erschienen in: Journal of Interventional Cardiac Electrophysiology | Ausgabe 1/2019

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Abstract

Purpose

Reconnection of pulmonary veins (PVs) remains common following radiofrequency catheter ablation for atrial fibrillation (AF). Ablation Index (AI) is a novel ablation quality marker that incorporates stability, contact force (CF), time, and power in a weighted formula. Its use seems to improve lesion durability. This is a prospective, single-arm registry to investigate on the safety and mid-term efficacy of AF ablation guided by the AI.

Methods

One hundred fifty-six consecutive patients (mean age 58 ± 10 years, 49% males, 44% with structural heart disease) referred for paroxysmal (124) or persistent (32) AF underwent antral PV isolation using a surround flow CF-sensing catheter guided by the AI. Radiofrequency was delivered targeting interlesion distance ≤ 6 mm and Ablation Index of 330–350 at posterior wall and 400–450 at anterior wall.

Results

Mean overall procedure time was 95 ± 30 min with a mean fluoroscopy time of 5 ± 6 min. Mean ablation time was 26 ± 10 min, 627/628 targeted PV were isolated. One pericardial effusion and two groin hematomas were reported; none required intervention. During a mean follow-up of 14 ± 6 months, 17 (10.8%) (9% paroxysmal AF vs 22% persistent AF, p = 0.09) patients had an atrial arrhythmia recurrence.

Conclusions

PV ablation guided by AI resulted feasible, achieving a high rate of isolated PVs, with a low complication rate, and allowed a high single-procedure arrhythmia-free survival at 14 months.

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Titel: Safety and efficacy of atrial fibrillation ablation guided by Ablation Index module
verfasst von: Francesco Solimene
Vincenzo Schillaci
Gergana Shopova
Francesco Urraro
Alberto Arestia
Assunta Iuliano
Fabio Maresca
Alessia Agresta
Vincenzo La Rocca
Antonio De Simone
Giuseppe Stabile
Publikationsdatum: 30.07.2018
Verlag: Springer US
Erschienen in: Journal of Interventional Cardiac Electrophysiology / Ausgabe 1/2019
Print ISSN: 1383-875X
Elektronische ISSN: 1572-8595
DOI: https://doi.org/10.1007/s10840-018-0420-5

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