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Drugs
Erschienen in: Drugs 3/2015

01.02.2015 | R&D Insight Report

Secukinumab: First Global Approval

verfasst von: Mark Sanford, Kate McKeage

Erschienen in: Drugs | Ausgabe 3/2015

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Abstract

Secukinumab (Cosentyx™) is a fully human monoclonal antibody against interleukin-17A, formulated for intravenous and subcutaneous administration. It received its first global approval in Japan on 26 December 2014 for the treatment of psoriasis and psoriatic arthritis in adults who are not adequately responding to systemic therapies (except for biologic agents). In the USA and the EU, secukinumab was approved in early 2015 for the treatment of patients with moderate-to-severe plaque psoriasis. Secukinumab is also being investigated in patients with ankylosing spondylitis and rheumatoid arthritis. This article summarizes the milestones in the development of secukinumab leading to its first approval for the treatment of adult patients with psoriasis and psoriatic arthritis.
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Metadaten
Titel
Secukinumab: First Global Approval
verfasst von
Mark Sanford
Kate McKeage
Publikationsdatum
01.02.2015
Verlag
Springer International Publishing
Erschienen in
Drugs / Ausgabe 3/2015
Print ISSN: 0012-6667
Elektronische ISSN: 1179-1950
DOI
https://doi.org/10.1007/s40265-015-0359-0

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