Skip to main content
Erschienen in: International Journal of Clinical Pharmacy 3/2017

01.06.2017 | Research Article

Self-medication with antibiotics in Serbian households: a case for action?

verfasst von: Ana Tomas, Milica Paut Kusturica, Zdenko Tomić, Olga Horvat, Daniela Djurović Koprivica, Dragica Bukumirić, Ana Sabo

Erschienen in: International Journal of Clinical Pharmacy | Ausgabe 3/2017

Einloggen, um Zugang zu erhalten

Abstract

Background Irregular antibiotic use, including self-medication contributes to the development of antibiotic resistance. One method of accessing antibiotic use in the community is through obtaining an in house inventory of drugs. Objective The aim of this study was to investigate the extent of storage and self-medication with antibiotics agents in households in Novi Sad, Serbia. Setting Households in Novi Sad. Method The study was performed during a 4-month period (October 2015–January 2016) using a sample of 112 households in Novi Sad, Serbia. Two trained interviewers performed the survey by visiting each household. The study consisted of making an inventory of all drugs in household and a semi-structured interview about drug use practices and perceptions. Main outcome measure Number of antibiotics obtained without prescription. Results Out of 112 surveyed households, antibiotics were encountered in 55 (49.1%). Antibiotics constituted 11.98% (92/768) of total number of drug items in households. Out of all antibiotics in households, 41 (44.57%) were not in current use, and presented left-overs from previous treatment. Antibiotics were usually acquired with prescription (67, 67.7%), while about a quarter of packages were used for self-medication—purchased at pharmacy without prescription (19, 20.65%) or obtained through friends or family member (6, 6.52%).The most commonly used antibiotics for self-medication was amoxicillin (reported indications included common cold, cough, pharyngitis and tooth-ache). Conclusion Antibiotics were present in large share of households in Novi Sad. Self-medication with antibiotics and sale of antibiotics without prescription represent an important problem in Serbia.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat De Kraker ME, Jarlier V, Monen JC, Heuer OE, Van De Sande N, Grundmann H. The changing epidemiology of bacteraemias in Europe: trends from the European Antimicrobial Resistance Surveillance System. Clin Microbiol Infect. 2013;19(9):860–8.CrossRefPubMed De Kraker ME, Jarlier V, Monen JC, Heuer OE, Van De Sande N, Grundmann H. The changing epidemiology of bacteraemias in Europe: trends from the European Antimicrobial Resistance Surveillance System. Clin Microbiol Infect. 2013;19(9):860–8.CrossRefPubMed
2.
Zurück zum Zitat Goossens H, Ferech M, Vander Stichele R, Elseviers M, ESAC Project Group. Outpatient antibiotic use in Europe and association with resistance: a cross-national database study. Lancet. 2005;365(9459):579–873.CrossRefPubMed Goossens H, Ferech M, Vander Stichele R, Elseviers M, ESAC Project Group. Outpatient antibiotic use in Europe and association with resistance: a cross-national database study. Lancet. 2005;365(9459):579–873.CrossRefPubMed
4.
Zurück zum Zitat European Centre for Disease Prevention and Control. Antimicrobial resistance surveillance in Europe 2014. Annual report of the European Antimicrobial Resistance Surveillance Network [EARS-Net]. ECDC, Stockholm; 2015. European Centre for Disease Prevention and Control. Antimicrobial resistance surveillance in Europe 2014. Annual report of the European Antimicrobial Resistance Surveillance Network [EARS-Net]. ECDC, Stockholm; 2015.
5.
Zurück zum Zitat Bbosa GS, Mwebaza N. Global irrational antibiotics/antibacterial drugs use: a current and future health and environmental consequences. Microb Pathog Strateg Combat Them Sci Technol Educ. 2013;4(3):1645–55. Bbosa GS, Mwebaza N. Global irrational antibiotics/antibacterial drugs use: a current and future health and environmental consequences. Microb Pathog Strateg Combat Them Sci Technol Educ. 2013;4(3):1645–55.
6.
Zurück zum Zitat Paut Kusturica M, Tomić Z, Bukmirić Z, Horvat O, Pavlović N, Mikov M. Antibiotics in Serbian households: a source of potential health and enviromental threats. Cent Eur J Public Health. 2015;23(2):114–8.CrossRef Paut Kusturica M, Tomić Z, Bukmirić Z, Horvat O, Pavlović N, Mikov M. Antibiotics in Serbian households: a source of potential health and enviromental threats. Cent Eur J Public Health. 2015;23(2):114–8.CrossRef
7.
Zurück zum Zitat Kusturica MP, Tomic Z, Bukumiric Z, Ninkovic L, Tomas A, Stilinovic N, et al. Home pharmacies in Serbia: an insight into self-medication practice. Int J Clin Pharm. 2015;37(2):373–8.CrossRefPubMed Kusturica MP, Tomic Z, Bukumiric Z, Ninkovic L, Tomas A, Stilinovic N, et al. Home pharmacies in Serbia: an insight into self-medication practice. Int J Clin Pharm. 2015;37(2):373–8.CrossRefPubMed
8.
Zurück zum Zitat Cars O, Mölstad S, Melander A. Variation in antibiotic use in the European Union. Lancet. 2001;357:1851–3.CrossRefPubMed Cars O, Mölstad S, Melander A. Variation in antibiotic use in the European Union. Lancet. 2001;357:1851–3.CrossRefPubMed
9.
Zurück zum Zitat Grigoryan L, Monnet DL, Haaijer-Ruskamp FM, Bonten MJ, Lundborg S, Verheij TJ. Self-medication with antibiotics in Europe: a case for action. Curr Drug Saf. 2010;5(4):329–32.CrossRefPubMed Grigoryan L, Monnet DL, Haaijer-Ruskamp FM, Bonten MJ, Lundborg S, Verheij TJ. Self-medication with antibiotics in Europe: a case for action. Curr Drug Saf. 2010;5(4):329–32.CrossRefPubMed
10.
Zurück zum Zitat Versporten A, Bolokhovets G, Ghazaryan L, Abilova V, Pyshnik G, Spasojevic T, et al. Antibiotic use in eastern Europe: a cross-national database study in coordination with the WHO Regional Office for Europe. Lancet. 2014;14(5):381–7.CrossRefPubMed Versporten A, Bolokhovets G, Ghazaryan L, Abilova V, Pyshnik G, Spasojevic T, et al. Antibiotic use in eastern Europe: a cross-national database study in coordination with the WHO Regional Office for Europe. Lancet. 2014;14(5):381–7.CrossRefPubMed
12.
Zurück zum Zitat González J, Orero A, Prieto J. Storage of antibiotics in Spanish households. Rev Esp Quimioter. 2006;19(3):275–85.PubMed González J, Orero A, Prieto J. Storage of antibiotics in Spanish households. Rev Esp Quimioter. 2006;19(3):275–85.PubMed
13.
Zurück zum Zitat WHO. Introduction to drug utilization research. Oslo: WHO; 2003. WHO. Introduction to drug utilization research. Oslo: WHO; 2003.
14.
Zurück zum Zitat Orero A, Gonzalez J, Prieto J. Antibióticos en los hogares españoles. Implicaciones médicas y socioeconómicas [Antibiotics in Spanish households. Medical and socioeconomic implications. URANO Study Group]. Med Clin (Barc) 1997;109:782–5. (in Spanish). Orero A, Gonzalez J, Prieto J. Antibióticos en los hogares españoles. Implicaciones médicas y socioeconómicas [Antibiotics in Spanish households. Medical and socioeconomic implications. URANO Study Group]. Med Clin (Barc) 1997;109:782–5. (in Spanish).
15.
Zurück zum Zitat Ngokwey N. Home remedies and doctor’s remedies in Feira (Brasil). Soc Sci Med. 1995;40:1141–53.CrossRefPubMed Ngokwey N. Home remedies and doctor’s remedies in Feira (Brasil). Soc Sci Med. 1995;40:1141–53.CrossRefPubMed
16.
Zurück zum Zitat Stratchounski LS, Andreeva IV, Ratchina SA, Galkin DV, Petrotchenkova NA, Demin AA, et al. The inventory of antibiotics in Russian home medicine cabinets. Clin Infect Dis. 2003;37(4):498–505.CrossRefPubMed Stratchounski LS, Andreeva IV, Ratchina SA, Galkin DV, Petrotchenkova NA, Demin AA, et al. The inventory of antibiotics in Russian home medicine cabinets. Clin Infect Dis. 2003;37(4):498–505.CrossRefPubMed
17.
Zurück zum Zitat Sawalha A. Extent of storage and wastage of antibacterial agents in Palestinian households. Pharm World Sci. 2010;32(4):530–5.CrossRefPubMed Sawalha A. Extent of storage and wastage of antibacterial agents in Palestinian households. Pharm World Sci. 2010;32(4):530–5.CrossRefPubMed
19.
Zurück zum Zitat De Bolle L, Mehuys E, Adriaens E, Remon JP, Van Bortel L, Christiaens T. Home medication cabinets and self-medication: a source of potential health threats? Ann Pharmacother. 2008;42(4):572–9.CrossRefPubMed De Bolle L, Mehuys E, Adriaens E, Remon JP, Van Bortel L, Christiaens T. Home medication cabinets and self-medication: a source of potential health threats? Ann Pharmacother. 2008;42(4):572–9.CrossRefPubMed
20.
Zurück zum Zitat Wondimu A, Molla F, Demeke B, Eticha T, Assen A, et al. Household storage of medicines and associated factors in Tigray Region, Northern Ethiopia. PLoS ONE. 2015;10(8):e0135650.CrossRefPubMedPubMedCentral Wondimu A, Molla F, Demeke B, Eticha T, Assen A, et al. Household storage of medicines and associated factors in Tigray Region, Northern Ethiopia. PLoS ONE. 2015;10(8):e0135650.CrossRefPubMedPubMedCentral
21.
Zurück zum Zitat Aljinovic-Vucic V, Trkulja V, Lackovic Z. Content of home pharmacy and self-medication practices in households of pharmacy and medical students in Zagreb, Croatia: findings in 2001 with a reference to 1977. Croat Med J. 2005;46(1):74–80.PubMed Aljinovic-Vucic V, Trkulja V, Lackovic Z. Content of home pharmacy and self-medication practices in households of pharmacy and medical students in Zagreb, Croatia: findings in 2001 with a reference to 1977. Croat Med J. 2005;46(1):74–80.PubMed
22.
23.
24.
Zurück zum Zitat Richman P, Garra G, Eskin B, Nashed A, Cody R. Oral antibiotic use without consulting a physician: a survey of ED patient. Am J Emerg Med. 2001;19:57–60.CrossRefPubMed Richman P, Garra G, Eskin B, Nashed A, Cody R. Oral antibiotic use without consulting a physician: a survey of ED patient. Am J Emerg Med. 2001;19:57–60.CrossRefPubMed
25.
Zurück zum Zitat Bennadi D. Self-medication: a current challenge. J Basic Clin Pharm. 2014;5(1):19–23.CrossRef Bennadi D. Self-medication: a current challenge. J Basic Clin Pharm. 2014;5(1):19–23.CrossRef
26.
Zurück zum Zitat Väänänen MH, Pietilä K, Airaksinen M. Self-medication with antibiotics-does it really happen in Europe? Health Policy. 2006;77(2):166–71.CrossRefPubMed Väänänen MH, Pietilä K, Airaksinen M. Self-medication with antibiotics-does it really happen in Europe? Health Policy. 2006;77(2):166–71.CrossRefPubMed
27.
Zurück zum Zitat Matuz M, Benko R, Doro P, Hajdu E, Soos G. Non-prescription antibiotic use in Hungary. Pharm World Sci. 2007;29:695–8.CrossRefPubMed Matuz M, Benko R, Doro P, Hajdu E, Soos G. Non-prescription antibiotic use in Hungary. Pharm World Sci. 2007;29:695–8.CrossRefPubMed
28.
Zurück zum Zitat Saradamma RD, Higginbotham N, Nichter M. Social factors influencing the acquisition of antibiotics without prescription in Kerala State, south India. Soc Sci Med. 2000;50(6):891–903.CrossRefPubMed Saradamma RD, Higginbotham N, Nichter M. Social factors influencing the acquisition of antibiotics without prescription in Kerala State, south India. Soc Sci Med. 2000;50(6):891–903.CrossRefPubMed
29.
Zurück zum Zitat Jakovljevic M. Resource allocation strategies in Southeastern European health policy. Eur J Health Econ. 2013;14:153–9.CrossRefPubMed Jakovljevic M. Resource allocation strategies in Southeastern European health policy. Eur J Health Econ. 2013;14:153–9.CrossRefPubMed
30.
Zurück zum Zitat Vukmirovic S. Farmakoepidemiološki i farmakoterapijski aspekti upotrebe antibakterijskih lekova–usklađenost nacionalnih vodiča i lokalne rezistencije bakterija [Pharmacoepidemiological and pharmacotherapeutic aspects of antibacterial use—adherence to National guidelines and local resistance patterns] [dissertation]. Novi Sad (Serbia): Medical faculty of Novi Sad; 2013. Vukmirovic S. Farmakoepidemiološki i farmakoterapijski aspekti upotrebe antibakterijskih lekova–usklađenost nacionalnih vodiča i lokalne rezistencije bakterija [Pharmacoepidemiological and pharmacotherapeutic aspects of antibacterial use—adherence to National guidelines and local resistance patterns] [dissertation]. Novi Sad (Serbia): Medical faculty of Novi Sad; 2013.
31.
Zurück zum Zitat Morgan DJ, Okeke NI, Laxminarayan R, Perencevich NE, Weisenberg S. Non-prescription antimicrobial use worldwide: a systematic review. Lancet Infect Dis. 2011;11:692–701.CrossRefPubMedPubMedCentral Morgan DJ, Okeke NI, Laxminarayan R, Perencevich NE, Weisenberg S. Non-prescription antimicrobial use worldwide: a systematic review. Lancet Infect Dis. 2011;11:692–701.CrossRefPubMedPubMedCentral
32.
Zurück zum Zitat Grigoryan L, Burgerhof J, Haaijer-Ruskamp F, Degener J, Deschepper R, Monnet D, et al. Is self-medication with antibiotics in Europe driven by prescribed use? J Antimicrob Chemother. 2007;59(1):152–6.CrossRefPubMed Grigoryan L, Burgerhof J, Haaijer-Ruskamp F, Degener J, Deschepper R, Monnet D, et al. Is self-medication with antibiotics in Europe driven by prescribed use? J Antimicrob Chemother. 2007;59(1):152–6.CrossRefPubMed
Metadaten
Titel
Self-medication with antibiotics in Serbian households: a case for action?
verfasst von
Ana Tomas
Milica Paut Kusturica
Zdenko Tomić
Olga Horvat
Daniela Djurović Koprivica
Dragica Bukumirić
Ana Sabo
Publikationsdatum
01.06.2017
Verlag
Springer International Publishing
Erschienen in
International Journal of Clinical Pharmacy / Ausgabe 3/2017
Print ISSN: 2210-7703
Elektronische ISSN: 2210-7711
DOI
https://doi.org/10.1007/s11096-017-0461-3

Weitere Artikel der Ausgabe 3/2017

International Journal of Clinical Pharmacy 3/2017 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.