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Erschienen in: Current Allergy and Asthma Reports 1/2013

01.02.2013 | ANAPHYLAXIS AND DRUG ALLERGY (P LIEBERMAN AND S SPECTOR, SECTION EDITORS)

Skin Testing For Beta-Lactam Antibiotics: Impact of the Availability of a Major Determinant

verfasst von: Fatima S. Khan, Michael E. Weiss

Erschienen in: Current Allergy and Asthma Reports | Ausgabe 1/2013

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Abstract

Beta-lactam antibiotics are very effective agents for a variety of infections. In patients with beta-lactam allergy, these drugs are withheld due to fear of subsequent allergic reactions. Therefore, increasing their exposure to broad spectrum antibiotics, which are more costly, have greater side effects, and increase the risk of developing resistant organisms. Up to 90 % of patients with a proposed beta-lactam sensitivity can tolerate beta lactam agents after appropriate evaluation. Skin testing to beta-lactam agents is the gold standard in evaluating patients with type I, immediate hypersensitivity reactions. The robust negative predictive value of this test has yet to be surpassed by any other testing modality currently available.
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Metadaten
Titel
Skin Testing For Beta-Lactam Antibiotics: Impact of the Availability of a Major Determinant
verfasst von
Fatima S. Khan
Michael E. Weiss
Publikationsdatum
01.02.2013
Verlag
Current Science Inc.
Erschienen in
Current Allergy and Asthma Reports / Ausgabe 1/2013
Print ISSN: 1529-7322
Elektronische ISSN: 1534-6315
DOI
https://doi.org/10.1007/s11882-012-0323-y

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