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Current Pulmonology Reports

Erschienen in:

07.07.2020 | Sleeping and Breathing (A Abreu, Section Editor)

Sleep, Obstructive Sleep Apnea, and Chronic Alveolar Hypoventilation in Cystic Fibrosis: Role of Noninvasive Ventilation During Sleep

verfasst von: Pamela Barletta, Maria Tupayachi Ortiz, Alexandre R. Abreu, Matthias Salathe, Alejandro D. Chediak

Erschienen in: Current Pulmonology Reports | Ausgabe 3/2020

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Abstract

Purpose of Review

We describe sleep disturbances in patients with cystic fibrosis emphasizing treatment of abnormal breathing during sleep with noninvasive ventilation.

Recent Findings

Advances in treatment have transformed cystic fibrosis from a pediatric disorder to an adult condition. The increase in cystic fibrosis life expectancy renders these patients at high risk for nocturnal and diurnal respiratory failure. Hypoventilation during sleep precedes diurnal hypoventilation in cystic fibrosis. In advanced cases, noninvasive ventilation improves awake ABGs, respiratory muscle strength, dyspnea, subjective sleep quality, and level of daily activities and attenuates sleep hypoventilation.

Summary

Noninvasive ventilation can ameliorate symptoms and improve gas exchange, particularly in cystic fibrosis with advanced lung dysfunction. There is insufficient literature describing the effect of noninvasive ventilation on survival in cystic fibrosis.

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Titel: Sleep, Obstructive Sleep Apnea, and Chronic Alveolar Hypoventilation in Cystic Fibrosis: Role of Noninvasive Ventilation During Sleep
verfasst von: Pamela Barletta
Maria Tupayachi Ortiz
Alexandre R. Abreu
Matthias Salathe
Alejandro D. Chediak
Publikationsdatum: 07.07.2020
Verlag: Springer US
Erschienen in: Current Pulmonology Reports / Ausgabe 3/2020
Elektronische ISSN: 2199-2428
DOI: https://doi.org/10.1007/s13665-020-00252-0

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