Correction
Following publication of this article [1], we recently noticed that two subjects in this study were not assigned to the correct genetic groups. One of the AA homozygotes was incorrectly entered as a C allele carrier and we had the opposite situation for a second subject.
We have re-run the primary statistical analysis with the subjects assigned to their correct groups. The corrected analysis produced very similar results to our initial, published findings as we observed a significant treatment effect and a significant genotype x treatment interaction due to a higher degree of response in the AA homozygotes.
Anzeige
Correcting our dataset did result in very slight differences in the mean values for 40 k time. The changes are presented in Table 1.
Table 1
.
Genotype
|
Placebo
|
Caffeine
|
A. Original Data: 40-km cycling time for Placebo and Caffeine conditions for AA homozygotes and C-allele carriers
| ||
AA | 76.1 +/- 5.8 min | 72.4 +/- 4.2 min |
C | 72.2 +/- 4.2 min | 70.4 +/- 4.3 min |
B. Corrected Data: 40-km cycling time for Placebo and Caffeine conditions for AA homozygotes and C-allele carriers
| ||
AA | 75.1 +/- 6.1 min | 71.6 +/- 4.3 min |
C | 73.1 +/- 4.5 min | 71.6 +/- 4.4 min |
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.