Erschienen in:
01.06.2010 | Case Report
Substitution of corticosteroid with everolimus after lung transplantation: a pediatric case report
verfasst von:
Thibaut Caruba, Vanida Brunie, Véronique Bousseau, Romain Guillemain, Patrice Prognon, Dominique Bégué, Brigitte Sabatier
Erschienen in:
International Journal of Clinical Pharmacy
|
Ausgabe 3/2010
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Abstract
We report the case of a 12 year-old lung transplant recipient, in whom compressive epidural lipomatosis secondary to corticosteroid prompted us to replace prednisone with everolimus. Discontinuing corticosteroid treatment after lung transplantation is associated with a risk of graft rejection despite concomitant immunosuppressive therapy with tacrolimus and mycophenolate mofetil. During a follow-up of 18 months with everolimus instead of prednisone, we did not observe graft rejection. In parallel, all symptoms related to epidural compression disappeared within a month.