Introduction
Aim 1
Aim 2
Aim 3
Aim 4
Background
Young Adulthood as a Vulnerable Developmental Period
Risk Factors against Successful Transition to Adulthood among YLHIV
High Risk for ART Non-adherence
Economic Instability, Treatment Adherence, Mental Health, and Neurocognitive Functioning
Theoretical Models Guiding the Study
Asset theory
Developmental theory
Progress of the Suubi+Adherence study (original study)
Methods
Overview of the Suubi+Adherence Study (original study)
Current study
Inclusion Criteria
Ethics and Informed Consent
Sample Tracking, Retention and Attrition
Baseline/Wave 1 | Wave 2 | Wave 3 | Wave 4 | Wave 5 |
---|---|---|---|---|
N=702 | N=670, retention rate=95.4% (lost to follow-up n=32) | N=663, retention rate=94.4% (lost to follow-up n=39) | N=662, retention rate=94.3% (lost to follow-up n=40) | N=656, retention rate=93.4% (lost to follow-up n=46) |
Data collection
Variable | Measurement | Reliability | Timepoint |
---|---|---|---|
Demographics (Respondent: Adolescent Participant) | |||
Age; sex (assigned at birth), orphan status (single vs. double); socioeconomic status; family composition/structure; caregiver educational level | Socio-demographic questionnaire | n/a | aT1-RC, 12, 24, 36, 48 |
Moderators (Respondent: Adolescent Participant) | |||
Rural/urban/semi-urban; exposure to outside HIV/STI-related programs; economic/household income; asset accumulation | aT1-RC, 12, 24, 36, 48 | ||
Potential Mechanisms of Change (Respondent: Adolescent Participant) | |||
Self-efficacy | Adapted Tennessee Self-Concept Scale [147] (TSC-2) (pretested in Suubi Studies) | 0.81 | aT1-RC, 12, 24, 36, 48 |
Education plans/aspirations | Adapted Monitoring the Future Survey [148] | n/a | aT1-RC, 12, 24, 36, 48 |
Motivation to participate | n/a | aT1-RC, 12, 24, 36, 48 | |
Family Support | 0.77 0.69 0.91 | aT1-RC, 12, 24, 36, 48 | |
Family Stability | Socio-demographic questionnaire | n/a | aT1-RC, 12, 24, 36, 48 |
Hopelessness | Beck Hopelessness Scale [152] | 0.79 | aT1-RC, 12, 24, 36, 48 |
Self-esteem | Rosenberg Self-Esteem Scale [155] | 0.77-0.88 | aT1-RC, 12, 24, 36, 48 |
Condom Negotiation Self-Efficacy | Condom negotiation self-efficacy scale [156] | 0.80 | aT1-RC, 12, 24, 36, 48 |
Sexual Communication Skills | Sexual Communication Scale [157] | 0.80 | aT1-RC, 12, 24, 36, 48 |
Transitions (education, employment, residential independence, prosocial transition, relationship/marital status, pregnancy/parenthood | Demographics, MTF, Work history interview, Relationship assessment scale, Adolescent Sexual Behavior Assessment (ASBA), additional prosocial activities | aT1-RC, 12, 24, 36, 48 | |
Social Support | Multidimensional scale of perceived social support MSPSS [158] | 0.84 | aT1-RC, 12, 24, 36, 48 |
Access to services | .66-.83 | aT1-RC, 12, 24, 36, 48 | |
Cost of staff time, supplies, overhead for IDAs | Project records; Admin. Review | n/a | ongoing |
Substance misuse | n/a; 0.58-0.90 | aT1-RC, 12, 24, 36, 48 | |
HIV stigma/disclosure | aT1-RC, 12, 24, 36, 48 | ||
Cognitive function | 0.61-0.88, 0.76, 0.64-0.79, 0.66, 0.85-0.91 | aT1-RC, 12, 24, 36, 48 | |
Primary Outcomes (Respondent: Adolescent Participant) | |||
Viral load/Virologic Suppression* | Biomedical data: Viral load* | n/a | aT1-RC, 12, 24, 36, 48 |
Secondary Outcomes (Respondent: Adolescent Participant) | |||
Adherence | Self-Report Questionnaire, Pill Counts, adherence self-efficacy [172] | aT1-RC, 12, 24, 36, 48 | |
Financial/economic stability (savings and asset accumulation) | Bank statements, MIS IDA, and American Dream Policy Demonstration [173] | n/a | aT1-RC, 12, 24, 36, 48 |
Sexual risk taking behavior: | n/a | aT1-RC, 12, 24, 36, 48 | |
Mental Health Functioning | Center for Epidemiological Studies-Depression Scale (CES-D) [177] | 0.65 | aT1-RC, 12, 24, 36, 48 |
STIs | Biomedical data: Gonorrhea, Chlamydia, Trichomonas | n/a | aT1-RC, 12, 24, 36, 48 |