Skip to main content
Erschienen in: Rheumatology International 8/2006

01.06.2006 | Case Report

Systemic lupus erythematosus due to Epstein–Barr virus or Epstein–Barr virus infection provocating acute exacerbation of systemic lupus erythematosus?

verfasst von: Ozgur Kasapcopur, Yakup Ergul, Seyhan Kutlug, Cengiz Candan, Yildiz Camcioglu, Nil Arisoy

Erschienen in: Rheumatology International | Ausgabe 8/2006

Einloggen, um Zugang zu erhalten

Abstract

Systemic lupus erythematosus (SLE) is a rheumatologic disease characterized by an inflammatory destruction of the target organ systems of the body in an unknown way by autoantibodies formed against self-antigens. Infectious agents like Epstein–Barr virus (EBV), cytomegalovirus and parvovirus B19 may have a role in the occurrence or the exacerbation of the SLE. In this report, the clinical follow-up of a 14-year-old girl diagnosed with SLE following an EBV infection with bicytopenia, lymphadenomegaly and hepatomegaly is discussed. This case could support the role of viral infections in the etiology of SLE.
Literatur
1.
Zurück zum Zitat Tan EM, Cohen AS, Fries JF et al (1982) The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 25:1271–1277PubMedCrossRef Tan EM, Cohen AS, Fries JF et al (1982) The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 25:1271–1277PubMedCrossRef
2.
3.
Zurück zum Zitat Sekıgawa I, Nawata M, Seta N, Yamada M, Iıda I, Hashımoto H (2002) Cytomegalovirus infection in patients with systemic lupus erythematosus. Clin Exp Rheumatol 20:559–564PubMed Sekıgawa I, Nawata M, Seta N, Yamada M, Iıda I, Hashımoto H (2002) Cytomegalovirus infection in patients with systemic lupus erythematosus. Clin Exp Rheumatol 20:559–564PubMed
4.
Zurück zum Zitat Sekıgawa I, Ogasavara H, Kaneko H, Hıshıkawa T, Hashımoto H (2001) Retroviruses and autoimmunity. Intern Med 40:80–86PubMedCrossRef Sekıgawa I, Ogasavara H, Kaneko H, Hıshıkawa T, Hashımoto H (2001) Retroviruses and autoimmunity. Intern Med 40:80–86PubMedCrossRef
5.
Zurück zum Zitat James JA, Kaufman KM, Farris AD, Taylor-Albert E, Lehman TJ, Harley JB (1997) An increased prevalence of Epstein–Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus. J Clin Invest 100:3019–3026PubMedCrossRef James JA, Kaufman KM, Farris AD, Taylor-Albert E, Lehman TJ, Harley JB (1997) An increased prevalence of Epstein–Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus. J Clin Invest 100:3019–3026PubMedCrossRef
6.
Zurück zum Zitat Klein-Gitelman MS, Miller ML (2004) Systemic lupus erythematosus. In: Behrman RE, Kliegman RM, Jenson HB (eds) Nelson textbook of pediatrics, 17th edn. Saunders Company, pp 809–813 Klein-Gitelman MS, Miller ML (2004) Systemic lupus erythematosus. In: Behrman RE, Kliegman RM, Jenson HB (eds) Nelson textbook of pediatrics, 17th edn. Saunders Company, pp 809–813
7.
Zurück zum Zitat Sabbatini A, Bombardier S, Migiliorini P (1993) Autoantibodies from patients with systemic lupus erythematosus bind a shared sequence of SmD and Epstein–Barr virus encoded nuclear antigen EBNA 1. Eur J Immunol 23:1146–1152PubMedCrossRef Sabbatini A, Bombardier S, Migiliorini P (1993) Autoantibodies from patients with systemic lupus erythematosus bind a shared sequence of SmD and Epstein–Barr virus encoded nuclear antigen EBNA 1. Eur J Immunol 23:1146–1152PubMedCrossRef
8.
Zurück zum Zitat Bhimma R, Adhikari M, Coodiva HM (1995) Epstein–Barr virus induced systemic lupus erythematosus. S Afr Med J 85:899–900PubMed Bhimma R, Adhikari M, Coodiva HM (1995) Epstein–Barr virus induced systemic lupus erythematosus. S Afr Med J 85:899–900PubMed
9.
Zurück zum Zitat James JA, Kaufman KM, Farris AD, Taylor-Albert E, Lehman TJA (1997) An increased prevalence of Epstein–Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus. J Clin Invest 100:3019–3026PubMedCrossRef James JA, Kaufman KM, Farris AD, Taylor-Albert E, Lehman TJA (1997) An increased prevalence of Epstein–Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus. J Clin Invest 100:3019–3026PubMedCrossRef
10.
Zurück zum Zitat Tomita H, Yamada M, Sekigawa I, Yoshiike T, Lida N, Hashimoto H (2003) Systemic lupus erythematosus-like autoimmune abnormalities induced by bacterial infection. Clin Exp Rheumatol 21:497–499PubMed Tomita H, Yamada M, Sekigawa I, Yoshiike T, Lida N, Hashimoto H (2003) Systemic lupus erythematosus-like autoimmune abnormalities induced by bacterial infection. Clin Exp Rheumatol 21:497–499PubMed
11.
Zurück zum Zitat Dror Y, Blachar Y, Cohen P, et al (1998) Systemic lupus erythematosus associated with acute Epstein–Barr virus infection. Am J Kidney Dis 32:825–828PubMedCrossRef Dror Y, Blachar Y, Cohen P, et al (1998) Systemic lupus erythematosus associated with acute Epstein–Barr virus infection. Am J Kidney Dis 32:825–828PubMedCrossRef
12.
Zurück zum Zitat Verdolini R, Bugatti L, Giangiacomi M, Nicolini M, Filosa G, Cerio R (2002) Systemic lupus erythematosus induced by Epstein–Barr virus infection. Br J Dermatol 146:877–881PubMedCrossRef Verdolini R, Bugatti L, Giangiacomi M, Nicolini M, Filosa G, Cerio R (2002) Systemic lupus erythematosus induced by Epstein–Barr virus infection. Br J Dermatol 146:877–881PubMedCrossRef
13.
Zurück zum Zitat Ramelli GP, Marone C, Trunger B (1990) Acute kidney failure in infectious mononucleosis. Scheweiz Med Wochenschr 120:1590–1594 Ramelli GP, Marone C, Trunger B (1990) Acute kidney failure in infectious mononucleosis. Scheweiz Med Wochenschr 120:1590–1594
14.
Zurück zum Zitat Incaprera M, Rindi L, Bazzichi A, Garzelli C (1998) Potential role of the Epstein–Barr virus in systemic lupus erythematosus autoimmunity. Clin Exp Rheumatol 16:289–294PubMed Incaprera M, Rindi L, Bazzichi A, Garzelli C (1998) Potential role of the Epstein–Barr virus in systemic lupus erythematosus autoimmunity. Clin Exp Rheumatol 16:289–294PubMed
15.
Zurück zum Zitat Moon UY, Park SJ, Oh ST et al (2004) Patients with systemic lupus erythematosus have abnormally elevated Epstein–Barr virus load in blood. Arthritis Res Ther 6:295–302CrossRef Moon UY, Park SJ, Oh ST et al (2004) Patients with systemic lupus erythematosus have abnormally elevated Epstein–Barr virus load in blood. Arthritis Res Ther 6:295–302CrossRef
Metadaten
Titel
Systemic lupus erythematosus due to Epstein–Barr virus or Epstein–Barr virus infection provocating acute exacerbation of systemic lupus erythematosus?
verfasst von
Ozgur Kasapcopur
Yakup Ergul
Seyhan Kutlug
Cengiz Candan
Yildiz Camcioglu
Nil Arisoy
Publikationsdatum
01.06.2006
Verlag
Springer-Verlag
Erschienen in
Rheumatology International / Ausgabe 8/2006
Print ISSN: 0172-8172
Elektronische ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-005-0063-6

Weitere Artikel der Ausgabe 8/2006

Rheumatology International 8/2006 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.