Background
Biomedical and non-communicable diseases (NCDs) research
Cypriot healthcare system setting
World | EUR31 | Cyprus | |||||
---|---|---|---|---|---|---|---|
DALYs (000’s) | % | DALYs (000’s) | % | DALYs (000’s) | % | ||
All causes | 2,735,162 | 100 | 155,304 | 100 | 216.1 | 100 | |
Group 1 | Communicable, maternal, perinatal and nutritional conditions | 924,686 | 33.8 | 7548 | 4.9 | 8.1 | 3.7 |
Group 2 | Non-communicable diseases | 1,505,907 | 55.1 | 133,904 | 86.2 | 184.8 | 85.5 |
Malignant neoplasms | 222,567 | 8.1 | 30,228 | 19.5 | 35.1 | 16.2 | |
Trachea, bronchus, lung cancers | 38,307 | 1.40 | 6611 | 4.26 | 7.2 | 3.34 | |
Breast cancer | 17,644 | 0.65 | 2598 | 1.67 | 4.2 | 1.96 | |
Colon and rectum cancers | 17,370 | 0.64 | 3492 | 2.25 | 2.9 | 1.34 | |
Lymphomas, multiple myeloma | 9053 | 0.33 | 1355 | 0.87 | 2.1 | 0.96 | |
Prostate cancer | 5812 | 0.21 | 1420 | 0.91 | 2.0 | 0.91 | |
Diabetes mellitus | 58,810 | 2.2 | 4114 | 2.6 | 10.6 | 4.9 | |
Mental and behavioural disorders | 182,841 | 6.7 | 20,352 | 13.1 | 31 | 14.4 | |
Unipolar depressive disorders | 76,173 | 2.78 | 6428 | 4.14 | 11.6 | 5.37 | |
Alcohol use disorders | 31,998 | 1.17 | 3965 | 2.55 | 7.3 | 3.38 | |
Alzheimer’s disease and other dementias | 18,129 | 0.66 | 4780 | 3.08 | 4.7 | 2.17 | |
Anxiety disorders | 27,389 | 1.00 | 2561 | 1.65 | 3.8 | 1.78 | |
Drug use disorders | 15,120 | 0.55 | 1388 | 0.89 | 2.0 | 0.92 | |
Schizophrenia | 14,033 | 0.51 | 1230 | 0.79 | 1.8 | 0.82 | |
Cardiovascular diseases | 392,430 | 14.3 | 32,500 | 20.9 | 41.7 | 19.3 | |
Ischaemic heart disease | 165,223 | 6.04 | 13,882 | 8.94 | 20.7 | 9.57 | |
Stroke | 140,783 | 5.15 | 7942 | 5.11 | 6.9 | 3.21 | |
Respiratory diseases | 136,698 | 5.0 | 7983 | 5.1 | 11.1 | 5.1 | |
Chronic obstructive pulmonary disease | 92,118 | 3.37 | 4763 | 3.07 | 4.0 | 1.85 | |
Asthma | 25,114 | 0.92 | 1570 | 1.01 | 2.8 | 1.30 | |
Other non-communicable diseases | 512,560 | 18.7 | 38,726 | 24.9 | 55 | 25.5 | |
Group 3 | Injuries | 304,570 | 11.1 | 13,853 | 8.9 | 23.2 | 10.7 |
Aim and study importance
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Is Cyprus doing enough biomedical research relative to its wealth?
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Is its portfolio appropriately designed to address the main diseases in Cyprus?
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Is the research emphasis attributed to the five NCDs appropriate to the burden affecting the Cypriot population?
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What is the research in terms of citations and international collaborations of Cypriot institutions?
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What impact is this research having on the Cypriot healthcare system and are there means to improve it?
Methods
Research objectives
Data sources
Biomedical research output
Country performance comparison
Funding organisations
Research institutions
NCD research
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Cancer research (oncology): ONCOL
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Cardiovascular research, including stroke: CARDI
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Diabetes research: DIABE
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Mental disorders research: MENTH
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Respiratory disease research: RESPI
Disease burden
Research level of papers and journals of cited papers
NCD research application
Cancer research type
Clinical guidelines (CGs)
Newspapers in Cyprus
The newspaper search strategy in English | ||||
---|---|---|---|---|
ONCOL | CARDI | DIABE | MENTH | RESPI |
(cancer or leukaemi* or melanoma* or lymphoma*) and (research* or study or scientists or expert*) | (heart or stroke or blood pressure or hypertension) and (research* or study or scientists or expert*) | diabet* and (research* or study or scientists or expert*) | (addict* OR ADHD OR alcoholi* OR Alzheimer’s OR anorexia OR anxiety OR bipolar OR bulimia OR dementia OR depression OR hyperactivity OR schizophrenia OR self-harm* OR suicide*) and (research* or study or scientists or expert*) | (asthma or COPD or chronic obstructive pulmonary disease or allergic rhinitis or cystic fibrosis or emphysema) and (research* or study or scientists or expert*) |
(καρκίνος or καρκινικ* or λευχαιμία* or μελάνωμα* or λέμφωμα*) and (έρευνα* or μελέτη* or επιστήμονες* or ειδικός*) | (καρδι* or εγκεφαλικό or αρτηριακή πίεση or πίεση αίματος or υπέρταση) and (έρευνα* or μελέτη* or επιστήμονες* or ειδικός*) | (διαβήτης* or διαβητικ*) and (έρευνα* or μελέτη* or επιστήμονες* or ειδικός*) | (εξαρτ* or εθισμ* or ΔΕΠΥ or αλκοολικ* or Αλτσχάιμερ or ανορεξία or διπολική or βουλιμία or άνοια or κατάθλιψη or υπερκινητικότητα or σχιζοφρένια or αυτοτραυματισμός or αυτοκτονία*) and (έρευνα* or μελέτη* or επιστήμονες* or ειδικός*) | (άσθμα or ΧΑΠ or Χρόνια Αποφρακτική Πνευμονοπάθεια or αλλαργική ρινίτιδα or κυστική ίνωση or εμφύσημα) and (έρευνα* or μελέτη* or επιστήμονες* or ειδικός*) |
Policy documents and advisory committee members’ research portfolio
Results
Biomedical research output
NCD | Papers (N) | Papers (fract N) | Papers (fract %) |
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ONCOL | 189 | 74.9 | 39.6 |
CARDI | 182 | 81.6 | 44.8 |
DIABE | 18 | 8.0 | 44.4 |
MENTH | 67 | 37.4 | 55.9 |
RESPI | 12 | 4.8 | 39.9 |
TOTAL | 468 | 206.7 | 44.2 |
Country performance comparison
Disease burden and NCD research
Average annual percentage growth of biomedical and NCD research output
Year/NCD | BIOMED | ONCOL | CARDI | DIABE | MENTH | RESPI |
---|---|---|---|---|---|---|
2002 | 53 | 4 | 5 | 2 | 3 | 0 |
2003 | 46 | 5 | 9 | 0 | 2 | 0 |
2004 | 58 | 7 | 4 | 0 | 5 | 0 |
2005 | 74 | 6 | 11 | 0 | 3 | 0 |
2006 | 83 | 8 | 8 | 0 | 2 | 2 |
2007 | 88 | 7 | 12 | 2 | 3 | 0 |
2008 | 133 | 12 | 10 | 0 | 3 | 0 |
2009 | 184 | 20 | 19 | 0 | 3 | 0 |
2010 | 221 | 23 | 23 | 1 | 7 | 2 |
2011 | 220 | 22 | 28 | 3 | 9 | 2 |
2012 | 256 | 39 | 28 | 5 | 10 | 4 |
2013 | 326 | 36 | 38 | 5 | 17 | 2 |
AAPG (%) | 18.5 | 21.2 | 18.27 | – | 15.08 | – |
Research institutions
Institutions/NCD | ONCOL | CARDI | DIABE | MENTH | RESPI | TOTAL |
---|---|---|---|---|---|---|
UCY | 14.4 | 16.1 | 0.5 | 14.2 | 0.0 | 45.1 |
CUT | 10.3 | 10.4 | 1.0 | 5.9 | 2.2 | 29.8 |
NGH | 7.4 | 16.9 | 0.0 | 0.0 | 0.3 | 24.6 |
CIN | 7.8 | 13.2 | 1.3 | 0.2 | 0.0 | 22.5 |
BOC | 16.8 | 0.8 | 0.0 | 0.0 | 0.0 | 17.5 |
UNN | 2.0 | 0.4 | 0.7 | 6.0 | 0.2 | 9.3 |
FOREIGN | 114.1 | 100.4 | 10.0 | 30.6 | 7.2 | 262.3 |
Other CY institutions | 16.3 | 23.9 | 4.4 | 10.2 | 2.1 | 56.9 |
Total | 189 | 182 | 18 | 67 | 12 | 468 |
Main six CY institutions % | 30.0 | 25.4 | 23.8 | 38.8 | 26.6 | 29.9 |
Foreign % | 60.4 | 55.2 | 55.6 | 45.6 | 60.1 | 56.0 |
Other CY % | 9.7 | 19.5 | 20.6 | 15.5 | 13.3 | 14.1 |
Funding organisations
Type of funding organisation | Contribution (fractional counts) | Expenditure (€m/year) | Name of funding bodies |
---|---|---|---|
Government | 28.8 | 1.3 | |
Agencies | 24.3 | 1.1 | Cyprus Cardiovascular Disease Educational and Research Trust (CCDERT) |
Electricity Authority of Cyprus (AHK) | |||
Departments | 4.5 | 0.2 | Government of the Republic of Cyprus, including the Ministry of Health and the other 10 Ministries |
Private-non-profit | 20 | 0.9 | |
Charities | 2.4 | 0.1 | Anti-Cancer Society |
Cyprus Heart Foundation | |||
Cyprus Telethon | |||
Foundations | 3.7 | 0.2 | AG Leventis Foundation |
Cyprus Research Promotion Foundation | |||
Marfin Popular Bank | |||
Academic | 9.2 | 0.4 | Cyprus University of Technology |
University of Cyprus | |||
Other non-profit | 4.8 | 0.2 | Child Health Institute |
Cyprus Institute of Neurology & Genetics | |||
Cyprus Nurses and Midwives Association | |||
Industry | 2 | 0.1 | Private companies, e.g. Chemical Block Ltd. |
NCD research
Disease burden
NCD sub-diseases | DALYs, 2012 (%) | Research (papers), 2002–13 (%) |
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Ischaemic heart disease | 9.6 | 4.1 |
Unipolar depressive disorders | 5.4 | 5.0 |
Diabetes | 4.9 | 16 |
Alcohol use disorders | 3.4 | 1.3 |
Trachea, bronchus, lung cancers | 3.3 | 1.4 |
Stroke | 3.2 | 22.9 |
Alzheimer’s disease and other dementias | 2.2 | 4.1 |
Breast cancer | 2.0 | 16.2 |
Chronic obstructive pulmonary disease | 1.9 | 0.0 |
Anxiety disorders | 1.8 | 5.3 |
Hypertensive heart disease | 1.5 | 2.6 |
Colon and rectum cancers | 1.3 | 4.2 |
Cross-country collaboration
Research level of papers and journals of cited papers
NCD research application
Oncology research application
Cancer research type
Cardiovascular diseases
Diabetes research
Mental health disorders
Respiratory conditions
Clinical guidelines (CGs)
Newspapers in Cyprus
Policy documents and advisory committee members’ research portfolio
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Cyprus Anti-Drugs Council
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Cyprus Mental Health Commission
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Health Insurance Organisation
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National Bioethics Committee
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Patients’ Rights Commission