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Erschienen in: Journal of Assisted Reproduction and Genetics 2/2011

01.02.2011 | Assisted Reproduction Technologies

The effect of age on in vitro fertilization outcome: is too young possible?

verfasst von: Zohreh Nazemian, Navid Esfandiari, Murid Javed, Robert F. Casper

Erschienen in: Journal of Assisted Reproduction and Genetics | Ausgabe 2/2011

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Abstract

Purpose

The negative correlation between fecundity and age in women has been extensively documented although data on reproductive performance in very young women is sparse. The objective of this study was to determine whether age ≤25 years has an impact on reproductive outcome in women undergoing IVF-ET.

Methods

IVF outcome in 85 infertility patients aged 19–25 years was compared to that in 69 infertility patients aged 30–35 years. Primary outcomes included fertilization rates and embryo quality. Secondary outcomes were clinical pregnancy and miscarriage rates.

Results

The young patients (≤25 years) demonstrated a lower fertilization rate, and reduced number of top quality embryos. Although clinical pregnancy, and implantation rates were similar to their older counterparts (30–35 years), the young women had a significantly higher miscarriage rate.

Conclusion

Our results demonstrating poorer reproductive performance in very young patients were surprising and need further investigation.
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Metadaten
Titel
The effect of age on in vitro fertilization outcome: is too young possible?
verfasst von
Zohreh Nazemian
Navid Esfandiari
Murid Javed
Robert F. Casper
Publikationsdatum
01.02.2011
Verlag
Springer US
Erschienen in
Journal of Assisted Reproduction and Genetics / Ausgabe 2/2011
Print ISSN: 1058-0468
Elektronische ISSN: 1573-7330
DOI
https://doi.org/10.1007/s10815-010-9499-z

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