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Diabetologia

Erschienen in:

21.11.2018 | Review

The many secret lives of adipocytes: implications for diabetes

verfasst von: Philipp E. Scherer

Erschienen in: Diabetologia | Ausgabe 2/2019

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Abstract

Adipose tissue remains a cryptic organ. The ubiquitous presence of adipocytes, the different fat pads in distinct anatomical locations, the many different types of fat, in each case with their distinct precursor populations, and the ability to interchange into other types of fat cells or even de-differentiate altogether, offers a staggering amount of complexity to the adipose tissue organ as a whole. Adipose tissue holds the key to improving our understanding of systemic metabolic homeostasis. As such, understanding adipose tissue physiology offers the basis for a mechanistic understanding of the pathophysiology of diabetes. This review presents some of the lesser known aspects of this fascinating tissue, which consistently still offers much opportunity for the discovery of novel targets for pharmacological intervention.

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Titel: The many secret lives of adipocytes: implications for diabetes
verfasst von: Philipp E. Scherer
Publikationsdatum: 21.11.2018
Verlag: Springer Berlin Heidelberg
Erschienen in: Diabetologia / Ausgabe 2/2019
Print ISSN: 0012-186X
Elektronische ISSN: 1432-0428
DOI: https://doi.org/10.1007/s00125-018-4777-x

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