Skip to main content
Erschienen in: Clinical Oral Investigations 8/2016

03.02.2016 | Original Article

The oral-systemic disease connection: a retrospective study

verfasst von: Bobby K. Joseph, Leif Kullman, Prem N. Sharma

Erschienen in: Clinical Oral Investigations | Ausgabe 8/2016

Einloggen, um Zugang zu erhalten

Abstract

Objectives

The study aimed at determining the association between oral disease and systemic health based on panoramic radiographs and general health of patients treated at Kuwait University Dental Center. The objective was to determine whether individuals exhibiting good oral health have lower propensity to systemic diseases.

Materials and methods

A total of 1000 adult patients treated at Kuwait University Dental Center were randomly selected from the patient’s records. The general health of patients was assessed from the medical history of each patient recorded during their visit to the clinic. The number of reported diseases and serious symptoms were used to develop a medical index. The oral health of these patients was assessed from panoramic radiographs to create an oral index by evaluating such parameters as caries, periodontitis, periapical lesions, pericoronitis, and tooth loss.

Results

In a total of 887 patients, 43.8 % had an oral index between 3 and 8, of which significantly higher (62.1 %) patients were with medical conditions compared to those without (33.2 %; p < 0.001). The Spearmans’s correlation (rho’) revealed a positive correlation (rho’ = 0.360, p 0.001) between oral and medical index. Partial correlation, while controlling demographics, gender, nationality, and age, also showed a significant positive correlation (p < 0.001) between medical and oral index.

Conclusions

The findings of this study showed a significant association between oral health and general health and confirmed the findings of previous reports as regards the existing correlation between dental infections and medical disorders. These results are not indicative of a causal relationship when the diagnosis of oral disease was based primarily on radiographic findings. Future research needs to include prospective clinical and interventional studies.

Clinical relevance

The significance of the oral-systemic disease connection highlights the importance of preventing and treating oral disease which have profound medical implications on general health.
Literatur
1.
Zurück zum Zitat World Health Organisation. World Oral health report 2003. Continuous improvement of oral health in the 21st century. Geneva: World Health Organisation 2003. World Health Organisation. World Oral health report 2003. Continuous improvement of oral health in the 21st century. Geneva: World Health Organisation 2003.
2.
Zurück zum Zitat Lee PH, McGrath CPJ, Kong AYC, Lam TH (2013) Self-report poor oral health and chronic diseases: the Hong Kong family project. Community Dent Oral Epidemiol 41:451–458PubMed Lee PH, McGrath CPJ, Kong AYC, Lam TH (2013) Self-report poor oral health and chronic diseases: the Hong Kong family project. Community Dent Oral Epidemiol 41:451–458PubMed
3.
Zurück zum Zitat Yu YH, Chasman DI, Buring JE, Ridker PM (2015) Cardiovascular risks associated with incident and prevalent periodontal disease. J Clin Periodontol 42(1):21–28CrossRefPubMedPubMedCentral Yu YH, Chasman DI, Buring JE, Ridker PM (2015) Cardiovascular risks associated with incident and prevalent periodontal disease. J Clin Periodontol 42(1):21–28CrossRefPubMedPubMedCentral
4.
Zurück zum Zitat Pihlstrom BL, Buse JB (2014) Diabetes and periodontal therapy. J Am Dent Assoc 145(12):1208–1210CrossRefPubMed Pihlstrom BL, Buse JB (2014) Diabetes and periodontal therapy. J Am Dent Assoc 145(12):1208–1210CrossRefPubMed
5.
Zurück zum Zitat Tavares M, San Martin L (2014) Systemic diseases and oral health. Dent Clin N Am 58:797–814CrossRefPubMed Tavares M, San Martin L (2014) Systemic diseases and oral health. Dent Clin N Am 58:797–814CrossRefPubMed
6.
Zurück zum Zitat Joshipura KJ, Ritchie CS, Douglass CW (2000) Strength of evidence linking oral and systemic disease. Compend Contin Educ Dent 21:12–23 Joshipura KJ, Ritchie CS, Douglass CW (2000) Strength of evidence linking oral and systemic disease. Compend Contin Educ Dent 21:12–23
7.
Zurück zum Zitat Joshipura KJ (2002) The relationship between oral conditions and ischemic stroke and peripheral vascular disease. J Am Dent Assoc 133(Suppl 1):23S–30SCrossRefPubMed Joshipura KJ (2002) The relationship between oral conditions and ischemic stroke and peripheral vascular disease. J Am Dent Assoc 133(Suppl 1):23S–30SCrossRefPubMed
8.
Zurück zum Zitat Cullinan MP, Ford PJ, Seymour GJ (2009) Periodontal disease and systemic health: current status. Aust Dent J 54(1 Suppl):S62–S69CrossRefPubMed Cullinan MP, Ford PJ, Seymour GJ (2009) Periodontal disease and systemic health: current status. Aust Dent J 54(1 Suppl):S62–S69CrossRefPubMed
9.
Zurück zum Zitat Lockhart PB, Bolger AF, Papapanou PN, Osinbowale O, Trevisan M, et al. (2012) Periodontal disease and atherosclerotic vascular disease: does the evidence support an independent association?: a scientific statement form the American Heart Association. Circulation 125(20):2520–2544CrossRefPubMed Lockhart PB, Bolger AF, Papapanou PN, Osinbowale O, Trevisan M, et al. (2012) Periodontal disease and atherosclerotic vascular disease: does the evidence support an independent association?: a scientific statement form the American Heart Association. Circulation 125(20):2520–2544CrossRefPubMed
10.
Zurück zum Zitat Kantovitz KR, Pacson FM, Rontani RMP, Gaviao MBD (2006) Obesity and dental caries: a systematic review. Oral Health Prev Dent 4:137–144PubMed Kantovitz KR, Pacson FM, Rontani RMP, Gaviao MBD (2006) Obesity and dental caries: a systematic review. Oral Health Prev Dent 4:137–144PubMed
11.
Zurück zum Zitat Tramini P, Molinari N, Tentscher M, Demattei C, Schulte AG (2009) Association between caries experience and body mass index in 12-year-old French children. Caries Res 43(6):468–473CrossRefPubMed Tramini P, Molinari N, Tentscher M, Demattei C, Schulte AG (2009) Association between caries experience and body mass index in 12-year-old French children. Caries Res 43(6):468–473CrossRefPubMed
13.
Zurück zum Zitat Johnston L, Vieira AR (2014) Caries experience and overall health status. Oral Health Prev Dent 12(2):163–170PubMed Johnston L, Vieira AR (2014) Caries experience and overall health status. Oral Health Prev Dent 12(2):163–170PubMed
14.
Zurück zum Zitat Heitmann BL, Gamborg M (2008) Remaining teeth, cardiovascular morbidity and death among adult Danes. Prev Med 47:156–160CrossRefPubMed Heitmann BL, Gamborg M (2008) Remaining teeth, cardiovascular morbidity and death among adult Danes. Prev Med 47:156–160CrossRefPubMed
15.
Zurück zum Zitat Hung HC, Joshipura KJ, Colditz G, Mansson JE, Rimm EB, Speizer FE, Wilett WC (2004) The association between tooth loss and coronary disease in men and women. J Public Health Dent 64:209–215CrossRefPubMed Hung HC, Joshipura KJ, Colditz G, Mansson JE, Rimm EB, Speizer FE, Wilett WC (2004) The association between tooth loss and coronary disease in men and women. J Public Health Dent 64:209–215CrossRefPubMed
16.
Zurück zum Zitat Östberg AL, Nyholm M, Gullberg B, Råstam L, Lindblad U (2009) Tooth loss and obesity in a defined Swedish population. Scand J Public Health 37(4):427–433CrossRefPubMed Östberg AL, Nyholm M, Gullberg B, Råstam L, Lindblad U (2009) Tooth loss and obesity in a defined Swedish population. Scand J Public Health 37(4):427–433CrossRefPubMed
18.
Zurück zum Zitat Jansson L (2008) Association between alcohol consumption and dental health. J Clin Periodontol 35:379–384CrossRefPubMed Jansson L (2008) Association between alcohol consumption and dental health. J Clin Periodontol 35:379–384CrossRefPubMed
19.
Zurück zum Zitat Zubaid M, Rashed WA, Husain M, Mohammad BA, Ridha M, et al. (2004) A registry of acute myocardial infarction in Kuwait: patient characteristics and practice patterns. Can J Cardiol 20(8):783–787PubMed Zubaid M, Rashed WA, Husain M, Mohammad BA, Ridha M, et al. (2004) A registry of acute myocardial infarction in Kuwait: patient characteristics and practice patterns. Can J Cardiol 20(8):783–787PubMed
20.
22.
Zurück zum Zitat Relvas M, Diz P, Seoane J, Tomas I (2013) Oral health scales: design of an oral health scale of infectious potential. Med Oral Patol Oral Cir Bucal 18(4):e664–e670CrossRefPubMedPubMedCentral Relvas M, Diz P, Seoane J, Tomas I (2013) Oral health scales: design of an oral health scale of infectious potential. Med Oral Patol Oral Cir Bucal 18(4):e664–e670CrossRefPubMedPubMedCentral
23.
Zurück zum Zitat Janket SJ, Qvarnström M, Meurman JH, Baird AE, Nuutinen P, Jones A (2004) Asymptomatic dental score and prevalent coronary heart disease. Circulation 109:1095–1100CrossRefPubMed Janket SJ, Qvarnström M, Meurman JH, Baird AE, Nuutinen P, Jones A (2004) Asymptomatic dental score and prevalent coronary heart disease. Circulation 109:1095–1100CrossRefPubMed
24.
Zurück zum Zitat Rautemaa R, Lauhio A, Cullinan MP, Seymour GJ (2007) Oral infections and systemic disease- an emerging problem in medicine. Clin Microbiol Infect 13(11):1041–1047CrossRefPubMed Rautemaa R, Lauhio A, Cullinan MP, Seymour GJ (2007) Oral infections and systemic disease- an emerging problem in medicine. Clin Microbiol Infect 13(11):1041–1047CrossRefPubMed
25.
Zurück zum Zitat Thorstensson H, Johansson B. Does oral health say anything about survival in later life? (2009) Findings in a Swedish cohort of 80 + years at baseline. Community Dent Oral Epidemiol 37: 325–332 Thorstensson H, Johansson B. Does oral health say anything about survival in later life? (2009) Findings in a Swedish cohort of 80 + years at baseline. Community Dent Oral Epidemiol 37: 325–332
Metadaten
Titel
The oral-systemic disease connection: a retrospective study
verfasst von
Bobby K. Joseph
Leif Kullman
Prem N. Sharma
Publikationsdatum
03.02.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
Clinical Oral Investigations / Ausgabe 8/2016
Print ISSN: 1432-6981
Elektronische ISSN: 1436-3771
DOI
https://doi.org/10.1007/s00784-016-1725-3

Weitere Artikel der Ausgabe 8/2016

Clinical Oral Investigations 8/2016 Zur Ausgabe

Parodontalbehandlung verbessert Prognose bei Katheterablation

19.04.2024 Vorhofflimmern Nachrichten

Werden Personen mit Vorhofflimmern in der Blanking-Periode nach einer Katheterablation gegen eine bestehende Parodontitis behandelt, verbessert dies die Erfolgsaussichten. Dafür sprechen die Resultate einer prospektiven Untersuchung.

Invasive Zahnbehandlung: Wann eine Antibiotikaprophylaxe vor infektiöser Endokarditis schützt

11.04.2024 Endokarditis Nachrichten

Bei welchen Personen eine Antibiotikaprophylaxe zur Prävention einer infektiösen Endokarditis nach invasiven zahnärztlichen Eingriffen sinnvoll ist, wird diskutiert. Neue Daten stehen im Einklang mit den europäischen Leitlinienempfehlungen.

Zell-Organisatoren unter Druck: Mechanismen des embryonalen Zahnwachstums aufgedeckt

08.04.2024 Zahnmedizin Nachrichten

Der Aufbau von Geweben und Organen während der Embryonalentwicklung wird von den Zellen bemerkenswert choreografiert. Für diesen Prozess braucht es spezielle sogenannte „Organisatoren“. In einer aktuellen Veröffentlichung im Fachjournal Nature Cell Biology berichten Forschende durch welchen Vorgang diese Organisatoren im Gewebe entstehen und wie sie dann die Bildung von Zähnen orchestrieren.

Die Oralprophylaxe & Kinderzahnheilkunde umbenannt

11.03.2024 Kinderzahnmedizin Nachrichten

Infolge der Umbenennung der Deutschen Gesellschaft für Kinderzahnheilkunde in Deutsche Gesellschaft für Kinderzahnmedizin (DGKiZ) wird deren Mitgliederzeitschrift Oralprophylaxe & Kinderzahnheilkunde in Oralprophylaxe & Kinderzahnmedizin umbenannt. Aus diesem Grunde trägt die erste Ausgabe in 2024 erstmalig den neuen Titel.

Newsletter

Bestellen Sie unseren kostenlosen Newsletter Update Zahnmedizin und bleiben Sie gut informiert – ganz bequem per eMail.