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Archives of Osteoporosis

Erschienen in:

01.12.2023 | Original Article

The total number of patients with any of four major fragility fractures decreased during the first wave of the COVID-19 epidemic in Japan, commencing before the state of emergency declaration, which was not as enforceable as lockdown

verfasst von: Kenta Minato, Jung-ho Shin, Susumu Kunisawa, Kiyohide Fushimi, Yuichi Imanaka

Erschienen in: Archives of Osteoporosis | Ausgabe 1/2023

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Abstract

Summary

Durin g the first wave of the COVID-19 epidemic, the total number of patients with any of the four major fragility fractures, including both inpatients and first-visit outpatients, began to decline shortly before the state of emergency was declared, rather than immediately after it was declared.

Purpose

This study aimed to investigate the impact of public health measures in the first wave of the COVID-19 epidemic on the occurrence of major fragility fractures (MFFs).

Methods

Patients aged 50 years or older who were hospitalized or had an initial visit as an outpatient for an MFF, defined as a proximal femoral fracture (PFF), vertebral fragility fracture (VFF), distal radius fracture (DRF), or a proximal humeral fracture (PHF), were included in this study. Three-phase interrupted time-series analyses were performed to evaluate the impact of the voluntary event cancellation request in late February 2020 and the emergency declaration in early April 2020 on changes in the total number of patients, including inpatients and first-visit outpatients.

Results

A total of 166,560 patients with MFFs were included (92,767 PFFs, 26,158 VFFs, 33,869 DRFs, and 13,766 PHFs). From the end of February, in seven prefectures with high proportions of urbanization, decreasing trends were estimated for level changes and slope changes in the total number of patients with any of the four MFFs (level change: PFF; point estimate; − 13.5 (95% CI; − 43.4, 16.5), VFF; − 15.3 (− 32.2, 1.5), DRF; − 16.1 (− 39.9, 7.6), PHF; − 1.9 (− 13.6, 9.8), slope change: PFF; − 4.8 (− 14.0, 4.4), VFF; − 3.0 (− 8.1, 2.2), DRF; − 0.6 (− 7.9, 6.7), PHF; − 2.4 (− 6.0, 1.2)).

Conclusion

The findings suggested that the total number of patients with any of the four MFFs did not begin to decline from early April 2020 after the state of emergency was declared but earlier, in late February 2020.

Nur mit Berechtigung zugänglich

Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, Zhao X, Huang B, Shi W, Lu R, Niu P, Zhan F, Ma X, Wang D, Xu W, Wu G, Gao GF, Tan W (2019) China Novel Coronavirus Investigating and Research Team (2020) A novel coronavirus from patients with pneumonia in China. N Engl J Med 382(8):727–733CrossRef

Banerjee A, Pasea L, Harris S, Gonzalez-Izquierdo A, Torralbo A, Shallcross L, Noursadeghi M, Pillay D, Sebire N, Holmes C, Pagel C, Wong WK, Langenberg C, Williams B, Denaxas S, Hemingway H (2020) Estimating excess 1-year mortality associated with the COVID-19 pandemic according to underlying conditions and age: a population-based cohort study. Lancet 395(10238):1715–1725CrossRefPubMedPubMedCentral

Emanuel EJ, Persad G, Upshur R, Thome B, Parker M, Glickman A, Zhang C, Boyle C, Smith M, Phillips JP (2020) Fair allocation of scarce medical resources in the time of Covid-19. N Engl J Med 382(21):2049–2055CrossRefPubMed

Islam N, Sharp SJ, Chowell G, Shabnam S, Kawachi I, Lacey B, Massaro JM, D’Agostino RB Sr, White M (2020) Physical distancing interventions and incidence of coronavirus disease 2019: natural experiment in 149 countries. BMJ 370:m2743CrossRefPubMed

Borgström F, Karlsson L, Ortsäter G, Norton N, Halbout P, Cooper C, Lorentzon M, McCloskey EV, Harvey NC, Javaid MK, Kanis JA (2020) Fragility fractures in Europe: burden, management and opportunities. Arch Osteoporos 15(1):59CrossRefPubMedPubMedCentral

Anoushiravani AA, Barnes CL, Bosco JA 3rd, Bozic KJ, Huddleston JI, Kang JD, Ready JE, Tornetta P 3rd, Iorio R (2020) Reemergence of multispecialty inpatient elective orthopaedic surgery during the COVID-19 pandemic: guidelines for a new normal. J Bone Joint Surg Am 102(14):e79CrossRefPubMed

Slullitel PA, Lucero CM, Soruco ML, Barla JD, Benchimol JA, Boietti BR, Zanotti G, Comba F, Taype-Zamboni DR, Carabelli GS, Piccaluga F, Sancineto CF, Diehl M, Buttaro MA, HipFEIR [Hip Fracture in the Elderly – Institutional Register] Study Group (2020) Prolonged social lockdown during COVID-19 pandemic and hip fracture epidemiology. Int Orthop 44(10):1887–1895CrossRefPubMed

Hall AJ, Clement ND, Farrow L, MacLullich AMJ, Dall GF, Scott CEH, Jenkins PJ, White TO, Duckworth AD, IMPACT-Scot Study Group (2020) IMPACT-Scot report on COVID-19 and hip fractures. Bone Joint J 102(9):1219–1228CrossRefPubMed

Ogliari G, Lunt E, Ong T, Marshall L, Sahota O (2020) The impact of lockdown during the COVID-19 pandemic on osteoporotic fragility fractures: an observational study. Arch Osteoporos 15(1):156CrossRefPubMedPubMedCentral

10.

Greensmith TSW, Faulkner AC, Davies PSE, Sinnerton RJH, Cherry JV, Supparamaniam S, MacInnes A, Dalgleish S (2021) Hip fracture care during the 2020 COVID-19 first-wave: a review of the outcomes of hip fracture patients at a Scottish Major Trauma Centre. Surgeon 19(5):e318–e324CrossRefPubMedPubMedCentral

11.

Park C, Sugand K, Aframian A, Morgan C, Pakroo N, Gibbons C, Fertleman M, Nathwani D, Bhattacharya R, Sarraf KM (2022) Impact of COVID-19 pandemic on hip fractures: the central London experience COVID-related urgent geriatric hip trauma (COUGH) study COVERT ( COVid Emergency-Related Trauma and orthopaedics) collaborative. Ir J Med Sci 191(3):1005–1012CrossRefPubMed

12.

Mazeda C, Santos PB, Vilas-Boas P, Antão J, Barcelos A (2021) What happened to hip fragility fractures during COVID-19 pandemic? Acta Reumatol Port 46(3):252–256PubMed

13.

Amzallag N, Factor S, Shichman I, Ben-Tov T, Khoury A (2021) Hip fractures during the COVID-19 pandemic: demographics, treatment pathway, and outcomes. Isr Med Assoc J 23(8):484–489PubMed

14.

Ojeda-Thies C, Cuarental-García J, Ramos-Pascua LR (2021) Decreased volume of hip fractures observed during COVID-19 lockdown. Eur Geriatr Med 12(4):759–766CrossRefPubMedPubMedCentral

15.

Iyengar KP, Khatir M, Mohamed MKA, Kariya AD, Jain VK, Sangani C, Adam RF, Suraliwala K (2021) Characteristics and clinical outcomes of hip fracture patients during the first lockdown of COVID-19, lessons learnt: A retrospective cohort analysis. J Perioper Pract 31(12):446–453PubMed

16.

Pluskiewicz W, Wilk R, Adamczyk P, Hajzyk M, Swoboda M, Sladek A, Koczy B (2021) The incidence of arm, forearm, and hip osteoporotic fractures during early stage of COVID-19 pandemic. Osteoporos Int 32(8):1595–1599CrossRefPubMedPubMedCentral

17.

Paccou J, Lenne X, Ficheur G, Theis D, Cortet B, Bruandet A (2021) Analysis of hip fractures in france during the first COVID-19 lockdown in spring 2020. JAMA Netw Open 4(11):e2134972CrossRefPubMedPubMedCentral

18.

Nygren H, Kopra J, Kröger H, Kuitunen I, Mattila VM, Ponkilainen V, Rikkonen T, Sund R, Sirola J (2022) The effect of COVID-19 lockdown on the incidence of emergency department visits due to injuries and the most typical fractures in 4 Finnish hospitals. Acta Orthop 93:360–366CrossRefPubMedPubMedCentral

19.

Badr HS, Du H, Marshall M, Dong E, Squire MM, Gardner LM (2020) Association between mobility patterns and COVID-19 transmission in the USA: a mathematical modelling study. Lancet Infect Dis 20(11):1247–1254CrossRefPubMedPubMedCentral

20.

Lee M, Zhao J, Sun Q, Pan Y, Zhou W, Xiong C, Zhang L (2020) Human mobility trends during the early stage of the COVID-19 pandemic in the United States. PLoS ONE 15(11):e0241468CrossRefPubMedPubMedCentral

21.

Nagata S, Nakaya T, Adachi Y, Inamori T, Nakamura K, Arima D, Nishiura H (2021) Mobility change and COVID-19 in Japan: mobile data analysis of locations of infection. J Epidemiol 31(6):387–391CrossRefPubMedPubMedCentral

22.

Yabe T, Tsubouchi K, Fujiwara N, Wada T, Sekimoto Y, Ukkusuri SV (2020) Non-compulsory measures sufficiently reduced human mobility in Tokyo during the COVID-19 epidemic. Sci Rep 10(1):18053CrossRefPubMedPubMedCentral

23.

Kurita J, Sugawara T, Ohkusa Y (2021) Estimated effectiveness of school closure and voluntary event cancellation as COVID-19 countermeasures in Japan. J Infect Chemother 27(1):62–64CrossRefPubMed

24.

Imai N, Endo N, Shobugawa Y, Oinuma T, Takahashi Y, Suzuki K, Ishikawa Y, Makino T, Suzuki H, Miyasaka D, Sakuma M (2019) Incidence of four major types of osteoporotic fragility fractures among elderly individuals in Sado, Japan, in 2015. J Bone Miner Metab 37(3):484–490CrossRefPubMed

25.

Zhang B, Liu W, Lemon SC, Barton BA, Fischer MA, Lawrence C, Rahn EJ, Danila MI, Saag KG, Harris PA, Allison JJ (2020) Design, analysis, power, and sample size calculation for three-phase interrupted time series analysis in evaluation of health policy interventions. J Eval Clin Pract 26(3):826–841CrossRefPubMed

26.

Ministry of Health, Labour and Welfare. Visualizing the data: information on COVID-19 infections. https://covid19.mhlw.go.jp/en/. Accessed 6 November 2022

27.

Diop BZ, Ngom M, Pougué Biyong C, Pougué Biyong JN (2020) The relatively young and rural population may limit the spread and severity of COVID-19 in Africa: a modelling study. BMJ Glob Health 5(5):e002699CrossRefPubMedPubMedCentral

28.

Nomura S, Tanoue Y, Yoneoka D, Gilmour S, Kawashima T, Eguchi A, Miyata H (2021) Mobility patterns in different age groups in Japan during the COVID-19 pandemic: a small area time series analysis through March 2021. J Urban Health 98(5):635–641CrossRefPubMedPubMedCentral

29.

Sakuma M, Endo N, Oinuma T, Endo E, Yazawa T, Watanabe K, Watanabe S (2008) Incidence and outcome of osteoporotic fractures in 2004 in Sado City, Niigata Prefecture. Japan J Bone Miner Metab 26(4):373–378CrossRefPubMed

30.

Mithal A, Bonjour JP, Boonen S, Burckhardt P, Degens H, El Hajj FG, Josse R, Lips P, Morales Torres J, Rizzoli R, Yoshimura N, Wahl DA, Cooper C, Dawson-Hughes B, IOF CSA Nutrition Working Group (2013) Impact of nutrition on muscle mass, strength, and performance in older adults. Osteoporos Int 24(5):1555–66CrossRefPubMed

31.

Switzer JA, Gammon SR (2012) High-energy skeletal trauma in the elderly. J Bone Joint Surg Am 94(23):2195–2204CrossRefPubMed

Titel: The total number of patients with any of four major fragility fractures decreased during the first wave of the COVID-19 epidemic in Japan, commencing before the state of emergency declaration, which was not as enforceable as lockdown
verfasst von: Kenta Minato
Jung-ho Shin
Susumu Kunisawa
Kiyohide Fushimi
Yuichi Imanaka
Publikationsdatum: 01.12.2023
Verlag: Springer London
Erschienen in: Archives of Osteoporosis / Ausgabe 1/2023
Print ISSN: 1862-3522
Elektronische ISSN: 1862-3514
DOI: https://doi.org/10.1007/s11657-023-01297-9

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