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Erschienen in: Journal of Radiation Oncology 2/2018

04.03.2018 | Original Research

The use of stereotactic radiosurgery for benign spinal tumors: single institution experience

verfasst von: David Boyce-Fappiano, Erinma Elibe, M. Salim Siddiqui, Ian Lee, Jack Rock, Farzan Siddiqui

Erschienen in: Journal of Radiation Oncology | Ausgabe 2/2018

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Abstract

Objective

Benign tumors of the spine pose unique challenges as they are typically located in proximity to the spinal cord and are relatively radio-resistant. Surgery is usually the first line of treatment, but recurrence can be common. Stereotactic radiosurgery (SRS) is an effective treatment for malignant spine lesions. However, patients with benign tumors generally have longer life expectancies and may develop long-term treatment side-effects. Our institutional experience in treating benign tumors with SRS is presented to display its utility for symptom and local control.

Methods

A retrospective cohort analysis was performed at a single institution between 2001 and 2013. A total of 26 patients (61 vertebral levels) with benign spine tumors were treated. Electronic medical records were queried for clinical, neurological, and radiological examinations. Post-treatment pain, neurological, and radiographic control were the primary endpoints of this study.

Results

Five patients (19.2%) were deceased with a median survival time of 16.9 months. Follow-up to evaluate pain response was available for 23 (88%), neurological for 20 (77%), and radiographic for 23 patients (88%). Median follow-up time was 15.5 months. Total pain response was 82.6%. Neurological improvement and radiographic control were noted in 75 and 87% of patients. One case of radionecrosis of the sacrum and one case of axillary numbness were observed.

Conclusion

The results of SRS for benign tumors of the spine appear to be promising, and as a result SRS may have a role in treating benign spinal tumors for patients who are not surgical candidates.
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Metadaten
Titel
The use of stereotactic radiosurgery for benign spinal tumors: single institution experience
verfasst von
David Boyce-Fappiano
Erinma Elibe
M. Salim Siddiqui
Ian Lee
Jack Rock
Farzan Siddiqui
Publikationsdatum
04.03.2018
Verlag
Springer Berlin Heidelberg
Erschienen in
Journal of Radiation Oncology / Ausgabe 2/2018
Print ISSN: 1948-7894
Elektronische ISSN: 1948-7908
DOI
https://doi.org/10.1007/s13566-018-0345-8

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