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Medical Oncology

Erschienen in:

01.06.2015 | Review Article

Therapeutic potential of cancer stem cells

verfasst von: Chunguang Yang, Kunlin Jin, Yangping Tong, William Chi Cho

Erschienen in: Medical Oncology | Ausgabe 6/2015

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Abstract

Cancer stem cells (CSCs) play an important role in cancer growth, self-renewal, metastasis, recurrence and radio/chemotherapy. However, the underlying mechanisms remain elusive. In this review, we explore the roles of CSCs in cancer’s relapse and progression and discuss the biomarkers of CSCs to predict clinical outcome and their diagnostic potential. The different approaches of CSC therapies are also reviewed, including cytotoxic, radiation, differentiation and targeting signaling pathways. We also discuss the challenge of targeting CSCs in cancer therapy. In addition, non-coding RNAs in CSC therapies are also discussed.

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Titel: Therapeutic potential of cancer stem cells
verfasst von: Chunguang Yang
Kunlin Jin
Yangping Tong
William Chi Cho
Publikationsdatum: 01.06.2015
Verlag: Springer US
Erschienen in: Medical Oncology / Ausgabe 6/2015
Print ISSN: 1357-0560
Elektronische ISSN: 1559-131X
DOI: https://doi.org/10.1007/s12032-015-0619-6

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25.04.2024 | Nierenkarzinom | Nachrichten

Springer Medizin

Therapeutic potential of cancer stem cells

Abstract

Neu im Fachgebiet Onkologie

Adjuvante Immuntherapie verlängert Leben bei RCC

Alectinib verbessert krankheitsfreies Überleben bei ALK-positivem NSCLC

Bei Senioren mit Prostatakarzinom auf Anämie achten!

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Springer Medizin

Abstract

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