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Endocrine

Erschienen in:

01.10.2019 | Review

Thyroid hormone therapy of hypothyroidism in pregnancy

verfasst von: Zhongyan Shan, Weiping Teng

Erschienen in: Endocrine | Ausgabe 1/2019

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Abstract

Hypothyroidism is the most frequent pregnancy-related thyroid dysfunction, including overt and subclinical hypothyroidism. Studies show that even mild hypothyroidism may eventuate in adverse gestational outcomes and intellectual impairment of offspring. Women with overt hypothyroidism (OH) must be treated by levothyroxine (LT4) pre- and during pregnancy, however, it is controversial that when and how to initiate LT4 therapy and further optimize dosing so that pregnant women and their offspring may truly benefit. In the review we will analyze the changes in thyroid hormone requirements in pregnant women, the timing of LT4 treatment and adjustment of LT4 dose according to etiology in patients with hypothyroidism during pregnancy, and adjustment of LT4 after delivery.

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Titel: Thyroid hormone therapy of hypothyroidism in pregnancy
verfasst von: Zhongyan Shan
Weiping Teng
Publikationsdatum: 01.10.2019
Verlag: Springer US
Erschienen in: Endocrine / Ausgabe 1/2019
Print ISSN: 1355-008X
Elektronische ISSN: 1559-0100
DOI: https://doi.org/10.1007/s12020-019-02044-2

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