Skip to main content
Erschienen in: Osteoporosis International 5/2014

01.05.2014 | Original Article

Too Fit To Fracture: a consensus on future research priorities in osteoporosis and exercise

verfasst von: L. M. Giangregorio, N. J. MacIntyre, A. Heinonen, A. M. Cheung, J. D. Wark, K. Shipp, S. McGill, M. C. Ashe, J. Laprade, R. Jain, H. Keller, A. Papaioannou

Erschienen in: Osteoporosis International | Ausgabe 5/2014

Einloggen, um Zugang zu erhalten

Abstract

Summary

An international consensus process identified the following research priorities in osteoporosis and exercise: study of exercise in high-risk cohorts, evaluation of multimodal interventions, research examining translation into practice and a goal to examine fracture outcomes.

Introduction

To identify future research priorities related to exercise for people with osteoporosis with and without osteoporotic spine fracture via international consensus.

Methods

An international expert panel and representatives from Osteoporosis Canada led the process and identified opinion leaders or stakeholders to contribute. A focus group of four patient advocates identified quality of life, mobility, activities of daily living, falls, bone mineral density, and harms as outcomes important for decision-making. Seventy-five individuals were invited to participate in an online survey asking respondents to define future research priorities in the area of osteoporosis and exercise; the response rate was 57 %. Fifty-five individuals from seven countries were invited to a half-day consensus meeting; 60 % of invitees attended. The results of the online survey, knowledge synthesis activities, and results of the focus group were presented. Nominal group technique was used to come to consensus on research priorities.

Results

Research priorities included the study of exercise in high-risk cohorts (e.g., ≥ 65 years, low BMD, moderate/high risk of fracture, history of osteoporotic vertebral fractures, hyperkyphotic posture, functional impairments, or sedentary), the evaluation of multimodal interventions, research examining translation into practice, and a goal to examine fracture outcomes. The standardization of outcomes or protocols that could be evolved into large multicentre trials was discussed.

Conclusions

The research priorities identified as part of the Too Fit To Fracture initiative can be used to inform the development of multicentre collaborations to evaluate and implement strategies for engaging individuals with osteoporosis in a safe and effective exercise.
Literatur
1.
Zurück zum Zitat Ioannidis G, Papaioannou A, Hopman WM, Akhtar-Danesh N, Anastassiades T, Pickard L, Kennedy CC, Prior JC, Olszynski WP, Davison KS, Goltzman D, Thabane L, Gafni A, Papadimitropoulos EA, Brown JP, Josse RG, Hanley DA, Adachi JD (2009) CMAJ 181:265–271PubMedCentralPubMedCrossRef Ioannidis G, Papaioannou A, Hopman WM, Akhtar-Danesh N, Anastassiades T, Pickard L, Kennedy CC, Prior JC, Olszynski WP, Davison KS, Goltzman D, Thabane L, Gafni A, Papadimitropoulos EA, Brown JP, Josse RG, Hanley DA, Adachi JD (2009) CMAJ 181:265–271PubMedCentralPubMedCrossRef
2.
Zurück zum Zitat Hopkins RB, Tarride JE, Leslie WD, Metge C, Lix LM, Morin S, Finlayson G, Azimaee M, Pullenayegum E, Goeree R, Adachi JD, Papaioannou A, Thabane L (2013) Osteoporos Int 24:581–593PubMedCrossRef Hopkins RB, Tarride JE, Leslie WD, Metge C, Lix LM, Morin S, Finlayson G, Azimaee M, Pullenayegum E, Goeree R, Adachi JD, Papaioannou A, Thabane L (2013) Osteoporos Int 24:581–593PubMedCrossRef
3.
Zurück zum Zitat Howe TE, Shea B, Dawson LJ, Downie F, Murray A, Ross C, Harbour RT, Caldwell LM, Creed G (2011) Cochrane Database Syst Rev CD000333 Howe TE, Shea B, Dawson LJ, Downie F, Murray A, Ross C, Harbour RT, Caldwell LM, Creed G (2011) Cochrane Database Syst Rev CD000333
5.
Zurück zum Zitat Wactawski-Wende J, Larson JC, Cauley J, Chen Z, LaCroix A, LaMonte M, Leboff M, Ockene JK, Robbins J (2012) Physical activity and incident fracture in postmenopausal women: the women’s health initiative observational study. J Bone Miner Res 27[(Supp 1)] Wactawski-Wende J, Larson JC, Cauley J, Chen Z, LaCroix A, LaMonte M, Leboff M, Ockene JK, Robbins J (2012) Physical activity and incident fracture in postmenopausal women: the women’s health initiative observational study. J Bone Miner Res 27[(Supp 1)]
6.
Zurück zum Zitat Nikander R, Gagnon C, Dunstan DW, Magliano DJ, Ebeling PR, Lu ZX, Zimmet PZ, Shaw JE, Daly RM (2011) J Bone Miner Res 26:1638–1647PubMedCrossRef Nikander R, Gagnon C, Dunstan DW, Magliano DJ, Ebeling PR, Lu ZX, Zimmet PZ, Shaw JE, Daly RM (2011) J Bone Miner Res 26:1638–1647PubMedCrossRef
7.
Zurück zum Zitat Rikkonen T, Salovaara K, Sirola J, Karkkainen M, Tuppurainen M, Jurvelin J, Honkanen R, Alhava E, Kroger H (2010) J Bone Miner Res 25:2332–2340PubMedCrossRef Rikkonen T, Salovaara K, Sirola J, Karkkainen M, Tuppurainen M, Jurvelin J, Honkanen R, Alhava E, Kroger H (2010) J Bone Miner Res 25:2332–2340PubMedCrossRef
8.
Zurück zum Zitat Gillespie LD, Robertson MC, Gillespie WJ, Lamb SE, Gates S, Cumming RG, Rowe BH (2009) Cochrane Database Syst Rev CD007146 Gillespie LD, Robertson MC, Gillespie WJ, Lamb SE, Gates S, Cumming RG, Rowe BH (2009) Cochrane Database Syst Rev CD007146
9.
Zurück zum Zitat Kemmler W, von Stengel S, Bebenek M, Engelke K, Hentschke C, Kalender WA (2012) Osteoporos Int 23:1267–1276PubMedCrossRef Kemmler W, von Stengel S, Bebenek M, Engelke K, Hentschke C, Kalender WA (2012) Osteoporos Int 23:1267–1276PubMedCrossRef
11.
Zurück zum Zitat Englund U, Nordstrom P, Nilsson J, Bucht G, Bjornstig U, Hallmans G, Svensson O, Pettersson U (2011) Osteoporos Int 22:499–505PubMedCrossRef Englund U, Nordstrom P, Nilsson J, Bucht G, Bjornstig U, Hallmans G, Svensson O, Pettersson U (2011) Osteoporos Int 22:499–505PubMedCrossRef
12.
Zurück zum Zitat Jokinen H, Pulkkinen P, Korpelainen J, Heikkinen J, Keinanen-Kiukaanniemi S, Jamsa T, Korpelainen R (2010) Calcif Tissue Int 87:44–51PubMedCrossRef Jokinen H, Pulkkinen P, Korpelainen J, Heikkinen J, Keinanen-Kiukaanniemi S, Jamsa T, Korpelainen R (2010) Calcif Tissue Int 87:44–51PubMedCrossRef
13.
Zurück zum Zitat Maatta M, Terho E, Jokinen H, Pulkkinen P, Korpelainen J, Heikkinen J, Keinanen-Kiukaanniemi S, Jamsa T, Korpelainen R (2012) BMC Musculoskelet Disord 13:173PubMedCentralPubMedCrossRef Maatta M, Terho E, Jokinen H, Pulkkinen P, Korpelainen J, Heikkinen J, Keinanen-Kiukaanniemi S, Jamsa T, Korpelainen R (2012) BMC Musculoskelet Disord 13:173PubMedCentralPubMedCrossRef
14.
Zurück zum Zitat Morseth B, Ahmed LA, Bjornerem A, Emaus N, Jacobsen BK, Joakimsen R, Stormer J, Wilsgaard T, Jorgensen L (2012) Eur J Epidemiol 27:463–471PubMedCrossRef Morseth B, Ahmed LA, Bjornerem A, Emaus N, Jacobsen BK, Joakimsen R, Stormer J, Wilsgaard T, Jorgensen L (2012) Eur J Epidemiol 27:463–471PubMedCrossRef
15.
16.
Zurück zum Zitat Karinkanta S, Piirtola M, Sievanen H, Uusi-Rasi K, Kannus P (2010) Nat Rev Endocrinol 6:396–407PubMedCrossRef Karinkanta S, Piirtola M, Sievanen H, Uusi-Rasi K, Kannus P (2010) Nat Rev Endocrinol 6:396–407PubMedCrossRef
17.
Zurück zum Zitat Gillespie LD, Gillespie WJ, Robertson MC, Lamb SE, Cumming RG, Rowe BH (2003) Cochrane Database Syst Rev CD000340 Gillespie LD, Gillespie WJ, Robertson MC, Lamb SE, Cumming RG, Rowe BH (2003) Cochrane Database Syst Rev CD000340
21.
Zurück zum Zitat Giangregorio LM, MacIntyre NJ, Thabane L, Skidmore CJ, Papaioannou A (2013) Cochrane Database Syst Rev 1, CD008618PubMed Giangregorio LM, MacIntyre NJ, Thabane L, Skidmore CJ, Papaioannou A (2013) Cochrane Database Syst Rev 1, CD008618PubMed
22.
Zurück zum Zitat Sherrington C, Tiedemann A, Fairhall N, Close JC, Lord SR (2011) N S W Public Health Bull 22:78–83PubMedCrossRef Sherrington C, Tiedemann A, Fairhall N, Close JC, Lord SR (2011) N S W Public Health Bull 22:78–83PubMedCrossRef
23.
Zurück zum Zitat Papaioannou A, Morin S, Cheung AM, Atkinson S, Brown JP, Feldman S, Hanley DA, Hodsman A, Jamal SA, Kaiser SM, Kvern B, Siminoski K, Leslie WD (2010) CMAJ 182:1864–1873PubMedCentralPubMedCrossRef Papaioannou A, Morin S, Cheung AM, Atkinson S, Brown JP, Feldman S, Hanley DA, Hodsman A, Jamal SA, Kaiser SM, Kvern B, Siminoski K, Leslie WD (2010) CMAJ 182:1864–1873PubMedCentralPubMedCrossRef
25.
Zurück zum Zitat Giangregorio L, Papaioannou A, MacIntyre NJ, Ashe M, Heinonen A, Shipp K, Wark JD, McGill S, Keller H, Jain R, Laprade J, Cheung A (2012) Too Fit To Fracture: a consensus on exercise recommendations for individuals with osteoporosis and osteoporotic vertebral fractures. J Bone Miner Res 27[Suppl 1] Giangregorio L, Papaioannou A, MacIntyre NJ, Ashe M, Heinonen A, Shipp K, Wark JD, McGill S, Keller H, Jain R, Laprade J, Cheung A (2012) Too Fit To Fracture: a consensus on exercise recommendations for individuals with osteoporosis and osteoporotic vertebral fractures. J Bone Miner Res 27[Suppl 1]
26.
28.
Metadaten
Titel
Too Fit To Fracture: a consensus on future research priorities in osteoporosis and exercise
verfasst von
L. M. Giangregorio
N. J. MacIntyre
A. Heinonen
A. M. Cheung
J. D. Wark
K. Shipp
S. McGill
M. C. Ashe
J. Laprade
R. Jain
H. Keller
A. Papaioannou
Publikationsdatum
01.05.2014
Verlag
Springer London
Erschienen in
Osteoporosis International / Ausgabe 5/2014
Print ISSN: 0937-941X
Elektronische ISSN: 1433-2965
DOI
https://doi.org/10.1007/s00198-014-2652-2

Weitere Artikel der Ausgabe 5/2014

Osteoporosis International 5/2014 Zur Ausgabe

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.