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11085 Suchergebnisse für:

Gastrointestinal Stromal Tumor 

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  1. 23.04.2024 | Online First

    Efficacy and Safety of Endoscopic Resection for Gastric Gastrointestinal Stromal Tumors Originating from the Muscularis Propria

    Gastrointestinal stromal tumors (GISTs) are mesenchymal neoplasms originating from the interstitial cells of Cajal within the gastrointestinal tract [ 1 , 2 ]. Among these, the stomach represents the predominant site for GIST development …

  2. Open Access 01.12.2024 | OriginalPaper

    Feasibility and efficacy of minimally invasive limited resection for primary duodenal gastrointestinal stromal tumors: a retrospective cohort study

    Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract, of which 60% are located at the stomach and 30% are located at the small intestines [ 1 ]. The primary duodenal gastrointestinal stromal

  3. Open Access 05.04.2024 | Online First

    Retrospective observational cohort study of laparoscopic surgical strategies for gastrointestinal stromal tumors

    Laparoscopic surgery has been used to treat gastric submucosal tumors (SMTs). Laparoscopic and endoscopic cooperative surgery (LECS) has been used when subtotal resection has been difficult, which enabled resection of these tumors. In this study …

  4. Open Access 13.04.2024 | Online First

    English version of Japanese Clinical Practice Guidelines 2022 for gastrointestinal stromal tumor (GIST) issued by the Japan Society of Clinical Oncology

    The Japan Society of Clinical Oncology Clinical Practice Guidelines 2022 for gastrointestinal stromal tumor (GIST) have been published in accordance with the Minds Manual for Guideline Development 2014 and 2017. A specialized team independent of …

  5. 09.02.2024 | OriginalPaper

    Development and validation of a preoperative risk nomogram prediction model for gastric gastrointestinal stromal tumors

  6. 14.03.2024 | Online First

    Comparative Analysis of Enbloc or Piecemeal Removal After Enbloc Resection of Gastrointestinal Stromal Tumors

    Gastrointestinal stromal tumors (GISTs) are the most common tumors of mesenchymal tissue origin and account for 0.1–3.0% of malignant gastrointestinal tract tumors, with the stomach being the most frequent site (60–70%) [ 1 , 2 ]. The surgical …

  7. Open Access 01.12.2024 | OriginalPaper

    A case report of abdominal metastatic dermatofibrosarcoma protuberans misdiagnosed as gastrointestinal stromal tumor

    Dermatofibrosarcoma protuberans (DFSP) is a low-grade malignant soft-tissue tumor that originates from the skin. It has a slow onset in the early stages, non-specific clinical symptoms, low specificity, and can easily be overlooked, missed, or …

  8. Open Access 01.12.2024 | OriginalPaper

    Advanced gastrointestinal stromal tumor: reliable classification of imatinib plasma trough concentration via machine learning

    Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the digestive tract [ 1 ]. Acquired functional mutations in the tyrosine-protein kinase growth factor receptor proto-oncogene (KIT) and platelet-derived growth …

  9. Open Access 01.12.2024 | OriginalPaper

    The GIST of it all: management of gastrointestinal stromal tumors (GIST) from the first steps to tailored therapy. A bibliometric analysis

    Gastrointestinal stromal tumors (GIST) are malignant mesenchymal tumors deriving from lineage cells of interstitial cells of Cajal (ICC) with an annual incidence of approximately 1.2 per 10 5 individuals [ 1 ]. Most frequently observed locations …

  10. Open Access 01.12.2024 | OriginalPaper

    Clinical characteristics and prognostic analysis of postoperative recurrence or metastasis of low-risk gastrointestinal stromal tumors

    Gastrointestinal stromal tumor ( GIST ) is a rare tumor derived from interstitial cells of Cajal in the gastrointestinal tract. It is mostly caused by oncogenic activation mutations of KIT or PDGFRA genes [ 1 ]. The global incidence of GIST is …

  11. Open Access 01.12.2024 | OriginalPaper

    Convolutional neural network applied to preoperative venous-phase CT images predicts risk category in patients with gastric gastrointestinal stromal tumors

    Gastric gastrointestinal stromal tumors (GISTs) account for 60–65% of all GISTs, followed by GIST S of the small intestine (25–30%) and colorectal region (5%). GIST S derive from interstitial cells of Cajal (ICC), and have a potential for …

  12. 11.03.2024 | Online First

    Reply to comment on predicting the risk stratification of gastrointestinal stromal tumors using machine learning‑based ultrasound radiomics

  13. 05.03.2024 | Online First

    Uncommon Mimicker of a High-Grade Thyroid Carcinoma: Solitary Thyroid Metastasis of Gastrointestinal Stromal Tumor (GIST)

    A 33-year-old male was found to have a progressive right thyroid mass causing tracheal deviation and discomfort. His past medical history was remarkable for a gastric gastrointestinal stromal tumor (GIST) resected 10 years ago, with recurrent …

  14. 02.03.2024 | Online First

    Comment on “Predicting the risk stratification of gastrointestinal stromal tumors using machine learning-based ultrasound radiomics”

  15. Open Access 01.12.2024 | OriginalPaper

    Development of a multi-phase CT-based radiomics model to differentiate heterotopic pancreas from gastrointestinal stromal tumor

    Heterotopic pancreas (HP) is a congenital anomaly in which pancreatic tissue is separate from the main gland and lacks a continuous vascular or ductal connection [ 1 ]. HP is most commonly found in the upper gastrointestinal tract, such as the …

  16. 12.03.2024 | Online First

    Whole-lesion iodine map histogram analysis in the risk classification of gastrointestinal stromal tumors: comparison with single-slice iodine concentration measurements

    Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract [ 1 ]. GISTs originate from the interstitial cells of Cajal [ 2 ]. Approximately 10–30% of GISTs are clinically malignant, and all GISTs …

  17. Open Access 01.12.2024 | OriginalPaper

    Bacteremia from streptococcus constellatus revealing a gastrointestinal stromal tumor

    Sc is usually part of the normal flora of mouth and gastro-intestinal tract, but aggressive presentations are possible. They mainly consist in abscesses formation and this can occur in association with malignancy [ 1 ].

  18. 24.12.2023 | OriginalPaper

    FBXW7 regulates the sensitivity of imatinib in gastrointestinal stromal tumors by targeting MCL1

    Gastrointestinal stromal tumors (GISTs) are the most common malignant mesenchymal neoplasms of the gastrointestinal tract, and they arise from interstitial cells of the Cajal lineage, which rely on the development of gain-of-function mutations in …

  19. 17.01.2024 | Online First

    Segmental Duodenal Resection for Gastrointestinal Stromal Tumor

    Surgical management of duodenal gastrointestinal stromal tumors (GIST) remains challenging due to the anatomical complexity of the region. While pancreaticoduodenectomy is considered standard, it is associated with significant morbidity …

  20. 25.11.2023 | OriginalPaper

    Predicting the progression-free survival of gastrointestinal stromal tumors after imatinib therapy through multi-sequence magnetic resonance imaging

    Gastrointestinal stromal tumors (GIST) originate from the interstitial cells of Cajal in the gastrointestinal tract and account for approximately 5% of all soft tissue tumors [ 1 ]. The annual incidence is estimated to be between 6.8 and 14.5 cases …

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e.Medpedia

Seltene Tumoren des Gastrointestinaltraktes beim alten und geriatrischen Patienten (NET, GIST)

Geriatrische Onkologie
Die häufigsten mesenchymalen Tumoren des Gastrointestinaltrakts bei geriatrischen Patienten sind gastrointestinale Stromatumoren (GIST) und Leiomyome. Die Behandlung erfolgt individualisiert, wobei Imatinib wie bei jüngeren Patienten eine wichtige Option in der postoperativen und palliativen Therapie darstellt. Zu beachten sind insbesondere Komorbiditäten sowie unerwünschte Arzneimittelwirkungen und -interaktionen. Submuköse Tumoren (Lipome, Leiomyome, Granularzelltumoren) werden in Abhängigkeit von der Histologie beobachtet oder endoskopisch bzw. chirurgisch therapiert. Die neuroendokrine Tumoren (NET) können aufgrund ihrer hormoneller Aktivität und eines Karzinoid-Syndroms symptomatisch werden. Das Therapiekonzept besteht führend aus der chirurgischen Resektion und dem Einsatz von Somatostatin-Analoga bei Somatostatinrezeptor-positiven Tumoren. Bei fortgeschrittenen Tumoren werden auch bei älteren Patienten neue Substanzen wie Everolimus oder Multikinaseinhibitoren eingesetzt.

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