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15977 Suchergebnisse für:

Myocarditis 

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  1. 23.04.2024 | Online First

    NASCI case of the month: desmoplakin cardiomyopathy masquerading as acute myocarditis

    We present a case of a young patient with chest pain. Labs and cardiac imaging were suspicious for acute myocarditis. Genetic testing revealed a diagnosis of desmoplakin cardiomyopathy. Desmoplakin cardiomyopathy may be considered in patients with …

  2. 18.04.2024 | Online First

    Multimodality imaging of eosinophilic myocarditis (loeffler’s endocarditis) in a patient with idiopathic hypereosinophilic syndrome

    Eosinophilic myocarditis can result in endomyocardial fibrosis affecting both ventricles, leading to restrictive cardiomyopathy. Multimodality imaging is crucial for diagnosis, as demonstrated in this case of a patient presenting with symptoms of …

  3. Open Access 01.03.2024 | OriginalPaper

    Germline HAVCR2/TIM-3 Checkpoint Inhibitor Receptor Deficiency in Recurrent Autoinflammatory Myocarditis

    Myocarditis can be caused by viral infection, drug reaction or general inflammatory condition. To provide understanding on inflammatory myocarditis, we describe clinical, genetic, and immunological properties of a young male patient who suffered …

  4. Open Access 01.03.2024 | OriginalPaper

    Prognostic value of visual and quantitative CMR regional myocardial function in patients with suspected myocarditis

    According to updated Lake-Louise Criteria, impaired regional myocardial function serves as a supportive criterion in diagnosing myocarditis. This study aimed to assess visual regional wall motional abnormalities (RWMA) and novel quantitative …

  5. 07.02.2024 | ReviewPaper

    Fulminant Myocarditis Temporally Associated with COVID-19 Vaccination

  6. Open Access 01.12.2024 | OriginalPaper

    Pfizer COVID19 vaccine is not associated with acute cardiovascular events excluding myocarditis– a national self-controlled case series study

    The COVID19 pandemic, which is ongoing since early 2020, has had a profound impact globally, affecting the lives of millions of people: by the beginning of August 2023, over 692 million people worldwide have been diagnosed with SARS-CoV-2 virus …

  7. 28.03.2024 | Online First

    Pentraxin 3 in Myocarditis: Proof-of-Principle Assessment as a Diagnostic and Prognostic Biomarker

    Pentraxin 3 (PTX3) is an acute phase protein produced in various tissues in response to microbial and sterile stimuli, which regulates the inflammation outcomes. PTX3 has not been investigated in myocarditis. Our aim was to assess circulating and …

  8. 13.03.2024 | Online First

    Analysis of Cytokine Profiles in Pediatric Myocarditis Multicenter Study

    Acute myocarditis (AM) is an inflammatory disease of the heart muscle that can progress to fulminant myocarditis (FM), a severe and life-threatening condition. The cytokine profile of myocarditis in children, especially in relation to fulminant …

  9. Open Access 01.12.2024 | OriginalPaper

    Fulminant myocarditis during postoperative adjuvant chemotherapy for lung cancer with atezolizumab: a case report

    Immune-related adverse events (irAEs) associated with immune checkpoint inhibitors (ICIs) include myocarditis, which is rare but can have a rapid course. Although myocarditis has been reported with atezolizumab [ 1 ], there are no reports of …

  10. 26.02.2024 | BriefCommunication

    Exploring IL-1 inhibition in chronic refractory idiopathic myocarditis: emerging insights and perspectives

  11. 11.12.2023 | ReviewPaper

    Myocarditis in Athletes: Risk Factors and Relationship with Strenuous Exercise

    Amidst the SARS-CoV-2 pandemic, myocarditis in athletes has demanded increased attention primarily because of the risk of sudden cardiac death. While most athletes who experience myocardial inflammation recover, extensive measures for screening …

  12. 30.03.2024 | Online First

    An autopsy case of lung adenocarcinoma with immune checkpoint inhibitor-induced pneumonia and fulminant myocarditis following pembrolizumab administration: a case report

    Immune checkpoint inhibitors (ICIs) are the current standard of care for non-small-cell lung cancer (NSCLC). Myocarditis is a rare but serious immune-related adverse event (irAE) associated with ICI therapy. We present a patient who received a …

  13. 20.03.2024 | Online First

    Clinical Effect Analysis of Different Doses of Creatine Phosphate Sodium Combined with Immunoglobulin in the Treatment of Pediatric Viral Myocarditis

    The purpose of this paper was to unravel the clinical effect analysis of different doses of creatine phosphate sodium (CPS) combined with immunoglobulin in the treatment of pediatric viral myocarditis (VMC). One hundred and twenty children with …

  14. 29.12.2023 | Letter

    Effectiveness and safety of IL1 inhibition with anakinra in chronic refractory idiopathic myocarditis

    Myocarditis is a potentially life-threatening condition in which an intense inflammatory response involving cardiomyocytes leads to cardiac damage, clinically manifesting as cardiac contractile dysfunction and heart failure. Chronic myocarditis is …

  15. 23.01.2024 | OriginalPaper

    Clinical characteristics, diagnosis and management of nivolumab-induced myocarditis

    Nivolumab can cause fatal myocarditis. We aimed to analyze the clinical characteristics of nivolumab-induced myocarditis and provide evidence for clinical diagnosis, treatment, and prevention. Studies involving nivolumab-induced myocarditis were …

  16. 13.12.2023 | OriginalPaper

    The diagnosis and treatment of pediatric clinical myocarditis in China: a multicenter retrospective study

    This study aims to examine the clinical characteristics and outcomes of clinical myocarditis in pediatric patients in China. This is a multicenter retrospective study. Children diagnosed with clinical myocarditis from 20 hospitals in China and …

  17. Open Access 01.12.2024 | OriginalPaper

    Clinical characteristics and influencing factors of severe fever with thrombocytopenia syndrome complicated by viral myocarditis: a retrospective study

    Severe fever with thrombocytopenia syndrome (SFTS) is a zoonotic infectious disease caused by the SFTS virus (SFTSV) infection. SFTSV was first isolated and diagnosed from patient serum by Chinese researchers around 2010 [ 1 , 2 ]. From then until …

  18. Open Access 23.12.2023 | OriginalPaper

    Immune checkpoint inhibitor-related myositis and myocarditis: diagnostic pitfalls and imaging contribution in a real-world, institutional case series

    Immune checkpoints (IC), including the cytotoxic T lymphocyte antigen 4 (CTLA-4) and programmed cell death protein 1 (PD-1)/programmed cell death ligand 1 (PD-L1) signaling pathways, are key regulators of immune homeostasis through the …

  19. Open Access 01.12.2024 | OriginalPaper

    Pembrolizumab-induced myocarditis with complete atrioventricular block and concomitant myositis in a metastatic bladder cancer patient: a case report and review of the literature

    In recent years, immune checkpoint inhibitors (ICIs) have transformed the landscape of cancer treatment [ 1 ]. Malignant cells evade the recognition and destruction by the immune system by exploiting immune checkpoint receptors, such as the …

  20. 12.12.2023 | OriginalPaper

    The role of circulating biomarkers in predicting the 30-day mortality of immune checkpoint inhibitors-related myocarditis: a retrospective cohort study

    Immune checkpoint inhibitors-related myocarditis (ICIs-M) is a rare and highly lethal immune-related adverse events (irAEs) in common irAEs. This study aims to find circulating biomarkers that can reflect disease state and prognosis accurately. 48 …

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e.Medpedia

Myokarditis

Klinische Kardiologie
Eine Myokarditis kann sowohl im Rahmen von Infektionen als auch infolge von nichtinfektiösen Erkrankungen wie z. B. der Sarkoidose entstehen. Bei einem Großteil der durch Infektionen bedingten Myokarditiden kommt es zu einer spontanen Ausheilung der Erkrankung. Bei einem geringen Teil der Patienten/-innen mit Myokarditis kommt es allerdings zu einer chronisch progredienten Erkrankung mit konsekutiver Störung der myokardialen Funktion entsprechend dem klinischen Bild einer dilatativen Kardiomyopathie. Der Goldstandard für die Diagnose einer Myokarditis ist weiterhin die endomyokardiale Biopsie. Wichtig ist, dass die Myokardbiopsie histologisch, immunhistologisch und unter Verwendung molekularbiologischer Techniken auch virologisch exakt analysiert wird, um die verschiedenen Entitäten der Myokarditis exakt zu erfassen und dann mögliche kausale Therapieoptionen einleiten zu können. Als kausale Therapieoptionen stehen immunmodulatorische und antivirale Ansätze zur Verfügung.

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