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4904 Suchergebnisse für:

Sufentanil 

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  1. Open Access 01.12.2024 | OriginalPaper

    50% efficacy dose of intravenous lidocaine in supressing sufentanil-induced cough in children: a randomised controlled trial

    Opioids, including fentanyl and sufentanil, are widely used for the induction of anaesthesia because of their rapid onset, better analgesic effects, and favourable effect on cardiovascular stability. However, the administration of sufentanil can …

  2. Open Access 01.12.2024 | Erratum

    Retraction Note: Dose selection of central or peripheral administration of sufentanil affect opioid induced cough?: a prospective, randomized, controlled trial

    This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12871-024-02522-9.

  3. Open Access 01.12.2024 | OriginalPaper

    Effect of pretreatment with a small dose of esketamine on sufentanil-induced cough during anesthesia induction: a randomized controlled trial

    The frequent use of sufentanil as an induction agent is due to its strong analgesic properties, short duration of action, and cardiovascular stability. However, The cough caused by sufentanil can occur during anesthesia induction. The prevalence …

  4. Open Access 01.12.2024 | OriginalPaper

    Comparisons of fentanyl and sufentanil on recovery time after inguinal hernia repair in children: a randomized clinical trial

    The incidence of inguinal hernia was reported to range 1–5% in the pediatric population [ 1 ], with surgical repair of the hernia considered to be one of the most common surgical operations performed in children [ 2 ]. With advancements in …

  5. Open Access 01.12.2024 | OriginalPaper

    Comparison of the analgesic effect of dezocine and esketamine in combination with sufentanil respectively after laparoscopic cholecystectomy: a prospective randomized controlled study

    Acute cholecystitis, which is caused by gallstones, is a common clinical disease. Despite diverse treatment methods, laparoscopic cholecystectomy (LC) remains the gold standard for the surgical treatment of calculous cholecystitis [ 1 ]. Compared …

  6. Open Access 01.12.2024 | OriginalPaper

    Effects of adding low-dose esketamine to sufentanil and propofol sedation during cervical conization: a single-centre, randomized controlled trial

    Despite efforts by the World Health Organization to eliminate cervical cancer, it remains a leading cause of morbidity and mortality in developing countries. Cervical conization is a commonly used excisional surgery for the treatment of cervical …

  7. Open Access 01.12.2024 | OriginalPaper

    Comparison of the effects of esketamine, sufentanil, or lidocaine combined with propofol on tussis reflection during upper gastrointestinal endoscopy: study protocol for a randomised, two centre, three-blind, controlled trial

    The endoscopic technique is the most widely utilised method for the diagnosis and treatment of upper gastrointestinal (GI) diseases and is vital in clinical cases for the screening and treatment of upper GI tumours. However, without anaesthesia …

  8. Open Access 01.12.2023 | OriginalPaper

    A comparative study of esketamine-dexmedetomidine and sufentanil-dexmedetomidine for sedation and analgesia in lung tumor percutaneous radiofrequency ablation (PRFA): a randomized double-blind clinical trial

    Primary lung cancer is one of the most common malignant tumors worldwide and one of the most common causes of cancer death [ 1 ]. Surgery is regarded as the treatment of choice, but it may be risky in patients with advanced age, cardiopulmonary …

  9. Open Access 09.08.2023 | OriginalPaper

    Intraoperative Sufentanil Consumption and the Risk of Postoperative Nausea and/or Vomiting: A Retrospective Observational Study

    Post-operative nausea and/or vomiting (PONV) is a common post-operative adverse reaction [ 1 ]. Patients often rate PONV worse than post-operative pain, and this feeling is also linked to a decline in patient satisfaction [ 2 , 3 ]. Apfel score has …

  10. Open Access 01.12.2023 | OriginalPaper

    Effects of remimazolam combined with sufentanil on hemodynamics during anesthetic induction in elderly patients with mild hypertension undergoing orthopedic surgery of the lower limbs: a randomized controlled trial

    With the aging of the population, increasing numbers of elderly patients need surgical treatment. Hypertension is very common in elderly patients. Because elderly patients with hypertension generally have poor vascular elasticity, declining …

  11. Open Access 01.12.2023 | OriginalPaper

    Effect of intravenous induction with different doses of Esketamine combined with propofol and sufentanil on intraocular pressure among pediatric strabismus surgery: a randomized clinical trial

    Stable intraocular pressure is beneficial for maintaining the shape and function of the eyeball, essential for the prognosis of patients undergoing ophthalmic surgery or those with ophthalmic diseases. The sudden increase in intraocular pressure …

  12. Open Access 01.12.2023 | OriginalPaper

    Postoperative effect of sufentanil preemptive analgesia combined with psychological intervention on breast cancer patients

    Breast cancer is the most prevalent malignancy in women worldwide, accounting for approximately 25% of all kinds of cancers [ 1 ]. The latest cancer reports show that breast cancer is still in the first place among female malignancies, with new …

  13. 01.05.2023 | News

    Sufentanil

    Acute gastroparesis: case report
  14. Open Access 13.04.2023 | OriginalPaper

    Randomized controlled trial for anesthesia during gastroscopy: interactions between remimazolam and propofol in combination with sufentanil

    Anesthetic drugs often interact synergistically to achieve a greater sedative effect at lower doses and reduced concentration-dependent side effects. An optimal dose ratio should be selected to achieve the desired synergistic impacts. The dose …

  15. 10.06.2023 | OriginalPaper

    Sufentanil inhibits Pin1 to attenuate renal tubular epithelial cell ischemia–reperfusion injury by activating the PI3K/AKT/FOXO1 pathway

    In various clinical environments, such as some surgical operations and sepsis, consecutive renal dysfunctions occur due to renal blood flow interruption [ 1 ] and subsequent reperfusion, which is called renal ischemia–reperfusion injury (RIRI) [ 2 …

  16. Open Access 27.05.2023 | OriginalPaper

    Comparison of Recovery Effect for Sufentanil vs. Remifentanil Anesthesia in Elderly Patients Undergoing Curative Resection for Hepatocellular Carcinoma

    Hepatocellular carcinoma (HCC) is a common cancer in patients with chronic liver disease and is the leading cause of cancer-related mortality worldwide. According to the World Health Organization, HCC is responsible for over 800,000 new cases and …

  17. Open Access 01.12.2018 | OriginalPaper

    RETRACTED ARTICLE: Dose selection of central or peripheral administration of sufentanil affect opioid induced cough?: a prospective, randomized, controlled trial

    Opioid are frequently used as a pre-induction adjunct because of their strong analgesic properties, relatively short duration of action and minor disturbance of cardiovascular stability. Opioid-induced cough(OIC) during induction of general …

  18. 01.11.2022 | News

    Sufentanil

    Respiratory depression: case report
  19. 18.02.2023 | OriginalPaper

    Sufentanil combined with parecoxib sodium inhibits proliferation and metastasis of HER2-positive breast cancer cells and regulates epithelial-mesenchymal transition

    According to the Global Cancer Report published in 2020 [ 1 ], breast cancer has officially been replaced with lung cancer as the most common type of cancer in the world, and human epidermal growth factor receptor 2 (HER2)-positive patients …

  20. Open Access 03.12.2022 | OriginalPaper

    Sedation efficacy of different dose of remimazolam with sufentanil for nerve block in young and elderly patients: a randomized, controlled study

    Peripheral nerve block presents significant clinical benefits in perioperative pain management [ 1 ]. With advanced development in ultrasound technique and its guidance, this invasive procedure can be completed within several minutes. However, any …

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e.Medpedia

Opioide in der Anästhesiologie

Die Anästhesiologie
Seit vielen Jahrhunderten sind Opioide bis heute die wirksamsten Medikamente zur Linderung starker Schmerzen. Sie haben einen zentralen Platz in der Anästhesiologie, Intensiv- und Notfallmedizin sowie der modernen Schmerztherapie. Der Beginn der modernen Opioidforschung liegt im Jahr 1804, als der deutsche Chemiker und Apotheker Sertürner das Alkaloid Morphin aus dem Opiumsaft isolieren konnte. Über Fentanyl und den modifizierten Fentanylderivaten bis hin zu den neuesten Entwicklungen konnten bis heute zahlreiche analgetisch potente Substanzen synthetisch hergestellt werden, deren Pharmakologie und klinische Anwendung in diesem Kapitel erörtert werden.

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