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Erschienen in: Archives of Gynecology and Obstetrics 6/2011

01.06.2011 | General Gynecology

Transvaginal Doppler sonography for evaluation of irregular uterine bleeding with DMPA

verfasst von: Mostafa Hussein

Erschienen in: Archives of Gynecology and Obstetrics | Ausgabe 6/2011

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Abstract

Background

The main cause for discontinuation of depot medroxyprogesterone acetate (DMPA) use is irregular menstrual bleeding. The exact pathophysiological mechanisms of irregular bleeding have remained unclear. Transvaginal Doppler is a non-invasive method for studying changes in blood flow which may highlight the underlying pathology in those cases with irregular uterine bleeding. The aim of this study was to quantify the uterine and subendometrial microvasculature in DMPA users with irregular bleeding pattern in comparison to DMPA users with amenorrhea.

Study design

This is a case control study. Forty users of DMPA were divided into two groups: one group included 20 users with irregular uterine bleeding and the second group included 20 amenorrheic users. Pulsatility index (PI) and resistance index (RI) of uterine and subendometrial blood vessels were determined. Power Doppler Energy was used to quantify the signal percentage of the subendometrial area.

Results

There is significant reduction of PI and RI in the uterine artery and subendometrial microvasculature in cases of irregular uterine bleeding.

Conclusion

Irregular uterine bleeding with DMPA associated with increased perfusion of uterine and subendometrial blood vessels.
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Metadaten
Titel
Transvaginal Doppler sonography for evaluation of irregular uterine bleeding with DMPA
verfasst von
Mostafa Hussein
Publikationsdatum
01.06.2011
Verlag
Springer-Verlag
Erschienen in
Archives of Gynecology and Obstetrics / Ausgabe 6/2011
Print ISSN: 0932-0067
Elektronische ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-010-1569-z

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