Background
Methods
Study population
Intracoronary measurements and pressure-wire pullback
Calculation of indices in pullback tracing analysis
Quantitative coronary angiography (QCA)
Intravascular images and analysis
Myocardial perfusion imaging
Statistical analyses
Results
Practicality and safety of the mechanical auto-pullback system
Comparison of clinical characteristics between the abrupt and gradual groups
Abrupt, n = l3 | Gradual, n = 7 | ||
---|---|---|---|
Age | 71.3 ± 12.2 | 71.9 ± 19.0 | 0.92 |
Prior MI. n (%) | 5 (38.4) | 2 (28.6) | 0.95 |
Male | 11 (84.6) | 6 (85.7) | 0.66 |
Diabetic mellitus | 4 (30.8) | 4 (57.1) | 0.25 |
Family history | 3 (23.0) | 2 (28.6) | 0.79 |
Dyslipidemia | 12 (92.3) | 3 (42.8) | 0.95 |
Hypertension | 10 (76.9) | 4 (57.1) | 0.36 |
Smoking | 7 (53.8) | 7 (100.0) | 0.10 |
Chronic kidney disease | 5 (38.5) | 3 (42.8) | 1.00 |
Proximal lesion | 12 (92.3) | 6 (85.7) | 1.00 |
Type B2/C | 10 (76.9) | 6 (85.7) | 1.00 |
Calcified lesion | 4 (30.8) | 2 (28.6) | 1.00 |
RD, mm | 2.65 ± 0.41 | 2.82 ± 0.59 | 0.43 |
%DS; % | 60.15 ± 16.89 | 53.81 ± 13.32 | 0.40 |
MLD, mm | 1.07 ± 0.52 | 1.27 ± 0.32 | 0.38 |
Lesion length | 19.02 ± 8.63 | 25.04 ± 12.59 | 0.22 |
Post-interventional MLD | 2.89 ± 2.48 | 2.74 ± 0.44 | 0.85 |
Post-interventional %DS, % | 14.39 ± 16.75 | −2.73 ± 8.43 | 0.02 |
Stent diameter, mm | 2.93 ± 0.30 | 2.93 ± 0.34 | 0.98 |
Stent length | 26.92 ± 13.33 | 28.57 ± 15.72 | 0.81 |
Multiple stenting, n (%) | 4 (30.8) | 4 (57.1) | 0.50 |
Abrupt, n = l 3 | Gradual, n = 7 | ||
---|---|---|---|
(a) Intravascular images parameters | |||
Lipid-rich plaque, n (%) | 8 (61.5) | 6 (85.7) | 0.95 |
Calcified plaque | 5 (38.5) | 1 (14.8) | 0.39 |
Plaque rupture | 4 (30.8) | 0 (0.0) | 0.22 |
Lesion length, mm | 28.34 ± 14.64 | 27.31 ± 14.97 | 0.89 |
Proximal ref. lumen area, mm2
| 6.78 ± 1.81 | 7.98 ± 14.97 | 0.32 |
Distal ref. lumen area | 5.42 ± 1.62 | 7.98 ± 14.97 | 0.11 |
Minimal lumen area | 1.75 ± 0.72 | 2.37 ± 0.49 | 0.06 |
Minimal stent area | 4.94 ± 1.55 | 5.61 ± 3.18 | 0.12 |
(b) Intracoronary pressure parameters | |||
Pre-interventional FFR | 0.59 ± 0.11 | 0.74 ± 0.03 | <0.01 |
Distal Pd/Pa | 0.66 ± 0.12 | 0.78 ± 0.03 | 0.02 |
Proximal Pd/Pa | 0.94 ± 0.05 | 0.93 ± 0.07 | 0.31 |
Physiological lesion length, mm | 20.36 ± 14.53 | 35.37 ± 20.40 | 0.07 |
Lesion AFFR | 0.29 ± 0.15 | 0.15 ± 0.05 | 0.01 |
Post-interventional FFR | 0.81 ± 0.05 | 0.84 ± 0.02 | 0.19 |
AFFR in-stent | 0.07 ± 0.05 | 0.05 ± 0.03 | 0.37 |
Pd/Pa at the proximal stent edge | 0.92 ± 0.05 | 0.95 ± 0.03 | 0.46 |
Pd/Pa at the distal stent edge | 0.88 ± 0.05 | 0.89 ± 0.05 | 0.91 |
Frame count | 8837.8 ± 1934.2 | 11234.0 ± 764.5 | <0.01 |
Pre-interventional FFRarea | 6554.7 ± 1576.0 | 9634.0 ± 687.0 | <0.01 |
Post-interventional FFRarea | 7987.3 ± 1747.4 | 10275.5 ± 735.8 | <0.01 |
%FFRarea | 16.21 ± 8.86 | 5.78 ± 3.90 | <0.01 |
D-FFR | 0.22 ± 0.10 | 0.10 ± 0.03 | <0.01 |